scholarly journals Expression of UPA and UPAR is associated with the clinical course of urinary bladder neoplasms

2002 ◽  
Vol 99 (5) ◽  
pp. 721-726 ◽  
Author(s):  
Maria Seddighzadeh ◽  
Gunnar Steineck ◽  
Per Larsson ◽  
Hans Wijkström ◽  
Ulf Norming ◽  
...  
Keyword(s):  
Urinary Bladder ◽  
Clinical Course ◽  
Bladder Neoplasms ◽  
Urinary Bladder Neoplasms

Polymorphisms inNQO1and the clinical course of urinary bladder neoplasms

2007 ◽  
Vol 41 (3) ◽  
pp. 182-190 ◽  
Author(s):  
Somali Sanyal ◽  
Charlotta Ryk ◽  
Petra J. De Verdier ◽  
Gunnar Steineck ◽  
Per Larsson ◽  
...  
Keyword(s):  
Urinary Bladder ◽  
Clinical Course ◽  
Bladder Neoplasms ◽  
Urinary Bladder Neoplasms

A Population-based Study of 538 Patients with Newly Detected Urinary Bladder Neoplasms Followed during 5 Years

2003 ◽  
Vol 37 (3) ◽  
pp. 195-201 ◽  
Author(s):  
Per Larsson ◽  
Hans Wijkström ◽  
Andreas Thorstenson ◽  
Jan Adolfsson ◽  
Ulf Norming ◽  
...  
Keyword(s):  
Urinary Bladder ◽  
Bladder Neoplasms ◽  
Urinary Bladder Neoplasms ◽  
Population Based ◽  
Population Based Study

Urinary bladder neoplasms: evaluation with contrast-enhanced MR imaging.

Radiology ◽  
1989 ◽  
Vol 172 (3) ◽  
pp. 739-743 ◽  
Author(s):  
J M Neuerburg ◽  
K Bohndorf ◽  
M Sohn ◽  
F Teufl ◽  
R W Guenther ◽  
...  
Keyword(s):  
Urinary Bladder ◽  
Mr Imaging ◽  
Bladder Neoplasms ◽  
Urinary Bladder Neoplasms ◽  
Contrast Enhanced

Contrast-Enhanced MR Imaging of Urinary Bladder Neoplasms

1990 ◽  
pp. 242-249
Author(s):  
J. M. Neuerburg ◽  
K. Bohndorf ◽  
M. Sohn ◽  
F. Teufl ◽  
R. W. Guenther ◽  
...  
Keyword(s):  
Urinary Bladder ◽  
Mr Imaging ◽  
Bladder Neoplasms ◽  
Urinary Bladder Neoplasms ◽  
Contrast Enhanced

Final Report on the Safety Assessment of Disperse Blue 1

1995 ◽  
Vol 14 (6) ◽  
pp. 433-451 ◽  
Keyword(s):  
Urinary Bladder ◽  
Skin Irritation ◽  
Bladder Neoplasms ◽  
Urinary Bladder Neoplasms ◽  
Female Rats ◽  
Final Report ◽  
Hair Dyes ◽  
Bladder Calculi ◽  
Male And Female Rats

The anthraquinone color Disperse Blue 1 is used in many nonoxidative hair dyes, colors and rinses. In vitro dermal penetration studies using skin from miniature pigs indicate this ingredient is poorly absorbed. All rats given Disperse Blue 1 orally at concentrations up to 3 g/kg survived. Reduced body weights and blue tissue samples were observed in short-term, subchronic, and chronic animal studies. No skin irritation was observed with concentrations up to 10%, but Disperse Blue 1 was a moderate sensitizer in guinea pigs. Disperse Blue 1 was mutagenic in several test systems. In feeding studies, the ingredient produced a significant increase in urinary bladder neoplasms in male and female rats. Equivocal results were reported in studies with male mice and negative results were reported for female mice. A dermal carcinogenesis study in mice was negative. Further evaluation of the carcinogenesis data suggests that the urinary bladder neoplasms appear to be associated with bladder calculi rather than arising from a genotoxic mechanism. Such bladder calculi do not appear to form in humans. Based upon these data and the facts that dermal exposure produced no evidence of carcinogenesis, that the ingredient is poorly absorbed, and that exposure to hair dyes is brief, it was concluded that Disperse Blue 1 is safe for use in hair dyes at concentrations up to 1%.

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