scholarly journals Identification of BRCA1 and BRCA2 carriers by allele-specific gene expression (AGE) analysis

2002 ◽  
Vol 98 (5) ◽  
pp. 732-736 ◽  
Author(s):  
Marco Montagna ◽  
Simona Agata ◽  
Arcangela De Nicolo ◽  
Chiara Menin ◽  
Gianni Sordi ◽  
...  
Keyword(s):  
Gene Expression ◽  
Specific Gene ◽  
Brca1 And Brca2 ◽  
Specific Gene Expression ◽  
Allele Specific

scholarly journals Random X Inactivation and Extensive Mosaicism in Human Placenta Revealed by Analysis of Allele-Specific Gene Expression along the X Chromosome

PLoS ONE ◽  
2010 ◽  
Vol 5 (6) ◽  
pp. e10947 ◽  
Author(s):  
Joana Carvalho Moreira de Mello ◽  
Érica Sara Souza de Araújo ◽  
Raquel Stabellini ◽  
Ana Maria Fraga ◽  
Jorge Estefano Santana de Souza ◽  
...  
Keyword(s):  
Gene Expression ◽  
X Chromosome ◽  
Human Placenta ◽  
X Inactivation ◽  
Specific Gene ◽  
Specific Gene Expression ◽  
Allele Specific

scholarly journals High-throughput analysis of candidate imprinted genes and allele-specific gene expression in the human term placenta

BMC Genetics ◽  
2010 ◽  
Vol 11 (1) ◽  
pp. 25 ◽  
Author(s):  
Caroline Daelemans ◽  
Matthew E Ritchie ◽  
Guillaume Smits ◽  
Sayeda Abu-Amero ◽  
Ian M Sudbery ◽  
...  
Keyword(s):  
Gene Expression ◽  
High Throughput ◽  
Specific Gene ◽  
Imprinted Genes ◽  
High Throughput Analysis ◽  
Human Term Placenta ◽  
Throughput Analysis ◽  
Term Placenta ◽  
Specific Gene Expression ◽  
Allele Specific

scholarly journals Allele-specific gene expression in a wild nonhuman primate population

2011 ◽  
Vol 20 (4) ◽  
pp. 725-739 ◽  
Author(s):  
J. TUNG ◽  
M. Y. AKINYI ◽  
S. MUTURA ◽  
J. ALTMANN ◽  
G. A. WRAY ◽  
...  
Keyword(s):  
Gene Expression ◽  
Nonhuman Primate ◽  
Specific Gene ◽  
Specific Gene Expression ◽  
Allele Specific ◽  
Primate Population

scholarly journals A SAGE study of apolipoprotein E3/3, E3/4 and E4/4 allele-specific gene expression in hippocampus in Alzheimer disease

2007 ◽  
Vol 36 (3) ◽  
pp. 313-331 ◽  
Author(s):  
Pu-Ting Xu ◽  
Yi-Ju Li ◽  
Xue-Jun Qin ◽  
Charles Kroner ◽  
Anya Green-Odlum ◽  
...  
Keyword(s):  
Gene Expression ◽  
Alzheimer Disease ◽  
Specific Gene ◽  
Specific Gene Expression ◽  
Allele Specific

scholarly journals PAC: Highly accurate quantification of allelic gene expression for population and disease genetics

2021 ◽  
Author(s):  
Anna Saukkonen ◽  
Helena Kilpinen ◽  
Alan Hodgkinson
Keyword(s):  
Gene Expression ◽  
Gene Regulation ◽  
Rna Sequencing ◽  
Specific Gene ◽  
Read Alignment ◽  
Specific Gene Expression ◽  
Powerful Approach ◽  
Allelic Gene ◽  
Allele Specific ◽  
Accurate Quantification

Analysis of allele-specific gene expression (ASE) is a powerful approach for studying gene regulation. However, detection of ASE events relies on accurate alignment of RNA-sequencing reads, where challenges still remain. We have developed PAC, a method that combines multiple steps to improve the quantification of allelic reads, including personalised (i.e. diploid) read alignment with improved allocation of multi-mapping reads. We show that PAC outperforms standard alignment approaches for ASE detection in both accuracy and in the number of sites it can reliably quantify.

scholarly journals Recovering genomes and phenotypes using allele-specific gene expression

2020 ◽  
Author(s):  
Gamze Gürsoy ◽  
Nancy Lu ◽  
Sarah Wagner ◽  
Mark Gerstein
Keyword(s):  
Gene Expression ◽  
Rna Sequencing ◽  
Specific Gene ◽  
Specific Gene Expression ◽  
Recent Increase ◽  
Variant Information ◽  
Allele Specific ◽  
The Individual

AbstractWith the recent increase in RNA sequencing efforts using large cohorts of individuals, studying allele-specific gene expression is becoming increasingly important. Here, we report that, despite not containing explicit variant information, a list of allele-specific gene names of an individual is enough to recover key variants and link the individual back to their genome or phenotype. This creates a privacy conundrum.

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