scholarly journals Laboratory management for large‐scale population screening for SARS‐CoV‐2

2021 ◽  
Author(s):  
Xiuzhi Duan ◽  
Dingfeng Lv ◽  
Lin Wang ◽  
Yanchao Liu ◽  
Shu Zhang ◽  
...  
Keyword(s):  
Large Scale ◽  
Population Screening ◽  
Laboratory Management ◽  
Scale Population

scholarly journals Is large-scale population screening coming to psychiatry?

2020 ◽  
Vol 2 (5) ◽  
pp. e210-e211
Author(s):  
Ioana Alina Cristea ◽  
Florian Naudet
Keyword(s):  
Large Scale ◽  
Population Screening ◽  
Scale Population

The feasibility of large scale population screening

1985 ◽  
Vol 72 (S1) ◽  
pp. s71-s72 ◽  
Author(s):  
G. Ekelund ◽  
U. Carlsson ◽  
L. Janzon
Keyword(s):  
Large Scale ◽  
Population Screening ◽  
Scale Population

scholarly journals Large scale population screening for Duchenne muscular dystrophy – Preliminary results

2022 ◽  
Vol 226 (1) ◽  
pp. S347
Author(s):  
Gal Cohen ◽  
Atalia Shtorch-Asor ◽  
Racheli Goldfarb-Yaacobi ◽  
Meirav Kaiser ◽  
Revital Rosenfeld ◽  
...  
Keyword(s):  
Duchenne Muscular Dystrophy ◽  
Muscular Dystrophy ◽  
Large Scale ◽  
Population Screening ◽  
Preliminary Results ◽  
Scale Population

A Blood Spot Assay for Apo A1 and B Lipoproteins and the Apo B/A1 Ratio

1993 ◽  
Vol 30 (5) ◽  
pp. 476-481 ◽  
Author(s):  
A D Hirst ◽  
K Beswick
Keyword(s):  
Blood Sample ◽  
Large Scale ◽  
Dried Blood Spots ◽  
Population Screening ◽  
Apo B ◽  
Blood Constituents ◽  
Blood Spots ◽  
Accuracy And Precision ◽  
Scale Population ◽  
Blood Spot

A study of conditions for the elution of apo A1 and B lipopoproteins from dried blood spots has led to the development of an apo B/A1 ratio assay with results for dried blood spots which are comparable with serum assays. This assay has been developed to be suitable for large scale population screening. The concept of measuring ratios for co-eluting blood constituents improves the accuracy and precision of blood spot assays and opens up the possibility that patients could take their own blood sample and send it to the laboratory by post.

scholarly journals Large-scale population screening for spinal muscular atrophy: Clinical implications

2011 ◽  
Vol 13 (2) ◽  
pp. 110-114 ◽  
Author(s):  
Shay Ben-Shachar ◽  
Avi Orr-Urtreger ◽  
Eyal Bardugo ◽  
Ruth Shomrat ◽  
Yuval Yaron
Keyword(s):  
Spinal Muscular Atrophy ◽  
Large Scale ◽  
Muscular Atrophy ◽  
Population Screening ◽  
Clinical Implications ◽  
Scale Population

scholarly journals A Multiplex qPCR Gene Dosage Assay for Rapid Genotyping and Large-Scale Population Screening for Deletional α-Thalassemia

2013 ◽  
Vol 15 (5) ◽  
pp. 642-651 ◽  
Author(s):  
Wanjun Zhou ◽  
Ge Wang ◽  
Xuefeng Zhao ◽  
Fu Xiong ◽  
Shaoxiong Zhou ◽  
...  
Keyword(s):  
Large Scale ◽  
Gene Dosage ◽  
Population Screening ◽  
Multiplex Qpcr ◽  
Scale Population

The Application of DNA Ploidy Analysis in Large-Scale Population Screening for Cervical Cancer

2021 ◽  
pp. 1-8
Author(s):  
Yulin Guo ◽  
Qiuzi Peng ◽  
Ying Wang ◽  
Lu Li ◽  
Xiaoyun Yi ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
Cancer Screening ◽  
Predictive Value ◽  
Large Scale ◽  
Dna Ploidy ◽  
Population Screening ◽  
Opportunistic Screening ◽  
Ploidy Analysis ◽  
Significant Difference ◽  
Scale Population

<b><i>Objective:</i></b> The objective of this study was to evaluate the application of DNA ploidy analysis in large-scale population screening for cervical cancer. <b><i>Methods:</i></b> From March 2016 to March 2019, eligible subjects were enrolled and recommended to undergo DNA ploidy analysis, the ThinPrep cytology test (TCT), and high-risk human papillomavirus (hrHPV) detection concurrently. Patients with positive results were recommended for colposcopy, and biopsy diagnosis was regarded as the “gold standard.” We compared the test efficiencies of the 3 methods and compared the efficiency and accuracy of the TCT in our hospital and the “2-cancer screening” project in Hubei Province during the same period. <b><i>Results:</i></b> Among 20,574 women, the positive rates of DNA ploidy analysis, cytology, and hrHPV testing were 4.01%, 4.71%, and 16.28%, respectively. The sensitivities of these methods for screening for grade 2+ cervical intraepithelial neoplasia were 0.70, 0.68, and 0.96, and their specificities were 0.79, 0.82, and 0.45, respectively. On comparing DNA ploidy analysis with the TCT, there was no significant difference in the sensitivity, specificity, positive predictive value, negative predictive value, and missed diagnosis rate. In opportunistic screening and the 2-cancer screening project, the positive rates of cytology were 4.71% and 2.87%, respectively. And the efficiency and accuracy of the TCT in opportunistic screening were higher than in the 2-cancer screening project. <b><i>Conclusion:</i></b> Therefore, DNA ploidy analysis, which is of low-cost and does not depend on cytopathologists, can replace cytology and be applied in large-scale population screening for cervical cancer.

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