scholarly journals Time‐related variation in IgG subclass concentrations in a group of healthy Danish adults

2021 ◽  
Author(s):  
Kristina Fruerlund Rasmussen ◽  
Ulrik Sprogøe ◽  
Christian Nielsen ◽  
Dana‐Bar Shalom ◽  
Kristian Assing
Keyword(s):  
Igg Subclass ◽  
Related Variation

DNA Typing for HLA-A and HLA-B Identifies Disparities Between Patients and Unrelated Donors Matched by HLA-A and HLA-B Serology and HLA-DRB1

Blood ◽  
1999 ◽  
Vol 93 (1) ◽  
pp. 399-409 ◽  
Author(s):  
Vinod K. Prasad ◽  
Nancy A. Kernan ◽  
Glenn Heller ◽  
Richard J. O’Reilly ◽  
Soo Young Yang
Keyword(s):  
Bone Marrow ◽  
Graft Versus Host Disease ◽  
Graft Failure ◽  
Dna Typing ◽  
Outcome Studies ◽  
Cancer Center ◽  
Host Disease ◽  
Graft Versus Host ◽  
Related Variation ◽  
Unrelated Donors

Abstract High incidences of graft failure and graft-versus-host disease in the recipients of bone marrow transplantations (BMT) from unrelated donors (URD) may reflect the existence of allelic disparities between the patient and the URD despite apparent HLA identity at HLA-A, HLA-B, and HLA-DRB1 loci. To identify the extent and pattern of allelic disparities at HLA-A and HLA-B loci, 128 patients and 484 potential URD were evaluated by DNA typing. DNA typing for HLA-A, HLA-B, and HLA-DRB1 was performed at Memorial Sloan Kettering Cancer Center. HLA-A and HLA-B serotyping on URD was provided by the registries. By original typing (serology for HLA-A and HLA-B; DNA typing for DRB1) 187, 164, and 133 URD were 6/6, 5/6, and 4/6 matches, respectively. Following DNA typing, however, only 52.9% of the originally 6/6 matched URD remained 6/6, while 38.5%, 7.5%, and 1.1% were found to be 5/6, 4/6, and 3/6 matches. The level of disparity was higher in the originally 5/6 (P< .01) and 4/6 (P < .01) matched URD. A higher level of disparity was seen for HLA-B as compared to HLA-A. In addition, a serotype related variation was also noticed. For example, 24.1% of HLA-A2 and 60.1% of HLA-B35 seromatched URD were genotypically disparate, but no disparities were seen for HLA-A1 and HLA-B8. A higher percentage of HLA-A (67.4%) compared with HLA-B (35.4%) serologic homozygous URD remained genotypically homozygous (P = .01). The level of allelic disparity was lower (P < .01 for 6/6; P = .02 for 5/6) if the patient had one of the 15 most common haplotypes (A1B8DR3, A2B7DR15, A3B7DR15, etc) in comparison to the rest of the group. Outcome studies will answer the question whether these disparities are associated with a higher rate of immunological complications seen with URD-BMT.

IgG Subclass Concentrations in Preterm Neonates

1984 ◽  
Vol 73 (5) ◽  
pp. 626-630 ◽  
Author(s):  
V.-A. OXELIUS ◽  
N. W. SVENNINGSEN
Keyword(s):  
Preterm Neonates ◽  
Igg Subclass

scholarly journals Significant, quantifiable differences exist between IgG subclass standards WHO67/97 and ERM-DA470k and can result in different interpretation of results

2013 ◽  
Vol 46 (16-17) ◽  
pp. 1751-1755 ◽  
Author(s):  
Calum Wilson ◽  
Rosemary Ebling ◽  
Clara Henig ◽  
Tanya Adler ◽  
Roza Nicolaevski ◽  
...  
Keyword(s):  
Igg Subclass ◽  
Interpretation Of Results

IgG Subclass Distribution in Serum and Various Mucosal Fluids of HIV Type 1-Infected Subjects

2000 ◽  
Vol 16 (6) ◽  
pp. 583-594 ◽  
Author(s):  
M. Raux ◽  
L. Finkielsztejn ◽  
D. Salmon-Céron ◽  
H. Bouchez ◽  
J.L. Excler ◽  
...  
Keyword(s):  
Igg Subclass ◽  
Hiv Type 1

ELISA detection of human IgG subclass antibodies to Streptococcus mutans

1986 ◽  
Vol 87 (1) ◽  
pp. 95-102 ◽  
Author(s):  
S.J. Challacombe ◽  
M. Biggerstaff ◽  
C. Greenall ◽  
D.M. Kemeny
Keyword(s):  
Streptococcus Mutans ◽  
Igg Subclass ◽  
Human Igg
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