scholarly journals Immune characteristics correlating with HSV‐1 immune control and effect of squaric acid dibutyl ester on immune characteristics of subjects with frequent herpes labialis episodes

2019 ◽  
Vol 7 (1) ◽  
pp. 22-40 ◽  
Author(s):  
Hugh McTavish ◽  
Katherine W. Zerebiec ◽  
Jay C. Zeller ◽  
Laurie L. Shekels ◽  
Mark A. Matson ◽  
...  
Keyword(s):  
Squaric Acid ◽  
Herpes Labialis ◽  
Immune Control ◽  
Dibutyl Ester ◽  
Hsv 1

scholarly journals Spontaneous Regression of Palmar Warts after Suffering from Diffuse Contact Dermatitis against Alkyl Bromide

2021 ◽  
pp. 54-57
Author(s):  
Gyohei Egawa ◽  
Tetsuya Honda ◽  
Kenji Kabashima
Keyword(s):  
Contact Dermatitis ◽  
Spontaneous Regression ◽  
Squaric Acid ◽  
Alkyl Bromide ◽  
Verrucae Vulgaris ◽  
Systemic Contact Dermatitis ◽  
Dibutyl Ester

Contact immunotherapy with several sensitizing chemicals such as diphenylcyclopropenone (DPCP) or squaric acid dibutyl ester (SADBE) have been used for the treatment of recalcitrant or multiple warts. Here, we report a case of multiple verrucae vulgaris (VV) on the palm which spontaneously resolved after the development of systemic contact dermatitis against alkyl bromide. We considered that our case accidentally mimics contact immunotherapy against multiple VV. VV sometimes regress spontaneously, which may be triggered by accidental contact dermatitis, as shown in our case.

scholarly journals Pola dan terapi infeksi Herpes simpleks virus-1 pada rongga mulut di RSUP Dr. Hasan Sadikin Bandung periode 2013-2017The pattern and therapy of the Herpes simplex virus-1 infection in the oral cavity at Dr Hasan Sadikin Hospital Bandung in 2013-2017

2019 ◽  
Vol 3 (1) ◽  
pp. 57
Author(s):  
Farhani Azizah ◽  
Irna Sufiawati ◽  
Mieke Hemiawati Satari
Keyword(s):  
Herpes Simplex Virus ◽  
Herpes Simplex ◽  
Oral Cavity ◽  
Erythema Multiforme ◽  
Medical Records ◽  
Oral Disease ◽  
Herpes Labialis ◽  
Herpes Simplex Virus 1 ◽  
Simplex Virus ◽  
Hsv 1

Pendahuluan: Salah satu virus yang menginfeksi rongga mulut adalah Herpes Simpleks Virus-1 (HSV-1). Virus ini menjadi patogen utama pada berbagai macam inang dan dapat menyebabkan berbagai macam penyakit orofasial. Tatalaksana infeksi HSV-1 memiliki pola terapi yang beragam bergantung pada kondisi klinis pasien. Tujuan penelitian ini adalah memperoleh data mengenai pola dan terapi penyakit mulut karena infeksi HSV-1. Metode: Data yang dikumpulkan merupakan data sekunder berasal dari logbook dan rekam medik pasien di Poliklinik Gigi dan Mulut RSUP Dr. Hasan Sadikin Bandung periode 2013-2017. Sampel penelitian ditentukan menggunakan metode purposive sampling, yaitu rekam medik pasien dengan diagnosis penyakit mulut karena infeksi HSV-1. Hasil: Pola penyakit mulut pada instalasi rawat jalan yaitu Recurrent Intraoral Herpes (RIH) sebanyak 84,91%, Herpes Associated Erythema Multiforme (HAEM) 9,43%, Herpes labialis 3,77%, dan Primary Herpetic Gingivo Stomatitis (PHGS) 1,89%. Pola penyakit mulut pada rawat inap yaitu Recurrent Intraoral Herpes (RIH) sebanyak 85,71% dan Herpes labialis sebanyak 14,29%. Pemberian terapi sangat bervariatif yaitu kombinasi asiklovir, antiseptik, multivitamin, antiinflamasi steroid, NSAID, pelembab bibir, antibiotik, antihistamin, dan antifungal. Simpulan: Penyakit mulut karena infeksi HSV-1 yang paling sering ditemukan baik pada instalasi rawat jalan maupun rawat inap adalah recurrent intraoral herpes. Pemberian terapi yang paling sering digunakan pada instalasi rawat jalan yaitu kombinasi obat antiinflamasi steroid dan multivitamin, sedangkan pada instalasi rawat inap yaitu multivitamin dan kombinasi asiklovir, antiseptik, dan multivitamin.Kata kunci: Pola penyakit mulut, pola terapi, infeksi Herpes Simpleks Virus-1 ABSTRACTIntroduction: One of the viruses that infect the oral cavity is Herpes Simplex Virus-1 (HSV-1). This virus becomes the primary pathogen in various types of hosts and can cause various kinds of orofacial diseases. Management of HSV-1 infection has a diverse pattern of therapy depending on the clinical condition of the patient. The purpose of this study was to obtain data on the patterns and treatment of oral diseases due to HSV-1 infection. Methods: Data collected was secondary data from the logbook and medical records of patients at the Dental Polyclinic of Dr Hasan Sadikin Hospital Bandung in 2013-2017. The study sample was determined using a purposive sampling method, namely medical records of patients with a diagnosis of oral disease due to HSV-1 infection. Results: The pattern of oral disease in outpatient installations, namely Recurrent Intraoral Herpes (RIH) 84.91%, Associated Erythema Multiforme (HAEM) Herpes 9.43%, Herpes labialis 3.77%, and Primary Herpetic Gingivo Stomatitis (PHGS) 1.89%. The pattern of oral disease in inpatient installations, namely Recurrent Intraoral Herpes (RIH) as much as 85.71% and Herpes labialis 14.29%. Given therapy was very varied, namely a combination of acyclovir, antiseptic, multivitamin, anti-inflammatory steroid, NSAIDs, lip moisturisers, antibiotics, antihistamines, and antifungal. Conclusion: Oral disease due to HSV-1 infection that is most often found both in outpatient and inpatient installations is recurrent intraoral herpes. The most commonly used therapy in outpatient installations is a combination of steroid anti-inflammatory drugs and multivitamins, while in inpatient installations are multivitamins and a combination of acyclovir, antiseptic, and multivitamins.Keywords: Oral disease patterns, therapy patterns, Herpes Simplex Virus-1 infection

Immune Control of HSV-1 Latency

2005 ◽  
Vol 18 (3) ◽  
pp. 466-473 ◽  
Author(s):  
Vilma Decman ◽  
Michael L. Freeman ◽  
Paul R. Kinchington ◽  
Robert L. Hendricks
Keyword(s):  
Immune Control ◽  
Hsv 1

scholarly journals Immune-enhancing agents in autoimmune skin diseases – A review

2022 ◽  
Vol 0 ◽  
pp. 1-8
Author(s):  
Abel Francis ◽  
Anjali Rose Jose
Keyword(s):  
Lupus Erythematosus ◽  
Skin Diseases ◽  
Immunosuppressive Drugs ◽  
Squaric Acid ◽  
Discoid Lupus Erythematosus ◽  
Autoimmune Conditions ◽  
Life Threatening ◽  
Autoimmune Dermatoses ◽  
Dibutyl Ester ◽  
Systemic Agents

Immunosuppressive drugs are the main stay of treatment for autoimmune dermatoses. The main disadvantage of these drugs is the increased susceptibility to life-threatening infections. Hence, in recent years, there has been an enthusiastic search for newer groups of drugs that can reduce this risk. Immune enhancing agents are considered as the key players of future. Immune enhancers function by activating various elements of the immune system and thereby amplifying the immune responses. They can be specific or non-specific in action. The main autoimmune dermatoses where the benefits of these drugs have so far been utilized include alopecia areata, vitiligo, psoriasis, lichen planus, and discoid lupus erythematosus. Immunostimulants are available in both topical and systemic forms. Topical immune- enhancing agents include contact sensitizers (diphenylcyclopropenone, dinitrochlorobenzene, and squaric acid dibutyl ester), anthralin, topical zinc, and interferons. Systemic agents include levamisole, zinc, probiotics, and so on. The exact mechanism of action of some of these drugs and other autoimmune conditions where they can be benefited is not completely understood. Another therapeutic agent that may come up in the future is individualized vaccines. Let us look forward to the days when individualized vaccines work wonders in the management of autoimmune diseases.

Iatrogenic cutaneous lymphoid hyperplasia induced by squaric acid dibutyl ester

2021 ◽  
Author(s):  
Shunsuke Takahagi ◽  
Tomofumi Numata ◽  
Akio Tanaka ◽  
Michihiro Hide
Keyword(s):  
Lymphoid Hyperplasia ◽  
Squaric Acid ◽  
Dibutyl Ester

Childhood epidermolysis bullosa acquisita during squaric acid dibutyl ester immunotherapy for alopecia areata

2016 ◽  
Vol 176 (2) ◽  
pp. 491-494 ◽  
Author(s):  
L. Guerra ◽  
V. Pacifico ◽  
V. Calabresi ◽  
N. De Luca ◽  
D. Castiglia ◽  
...  
Keyword(s):  
Epidermolysis Bullosa ◽  
Alopecia Areata ◽  
Epidermolysis Bullosa Acquisita ◽  
Squaric Acid ◽  
Dibutyl Ester
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