scholarly journals Real-life effectiveness of MP-AzeFlu in Irish patients with persistent allergic rhinitis, assessed by visual analogue scale and endoscopy

2018 ◽  
Vol 6 (4) ◽  
pp. 456-464 ◽  
Author(s):  
Ranbir Kaulsay ◽  
Duc Tung Nguyen ◽  
Hans Christian Kuhl
2017 ◽  
Vol 47 (12) ◽  
pp. 1526-1533 ◽  
Author(s):  
D. Caimmi ◽  
N. Baiz ◽  
L. K. Tanno ◽  
P. Demoly ◽  
S. Arnavielhe ◽  
...  

2018 ◽  
Vol 32 (3) ◽  
pp. 121-131 ◽  
Author(s):  
A. Koskinen ◽  
J. Numminen ◽  
A. Markkola ◽  
J. Karjalainen ◽  
T. Karstila ◽  
...  

Objectives The diagnosis of chronic rhinosinusitis without nasal polyps (CRSsNP) and distinguishing it from allergic rhinitis is difficult. Yet, early detection of CRSsNP is important to prevent progressive and severe chronic rhinosinusitis. Our aim was to compare diagnostic accuracy of symptoms, endoscopy, and imaging signs of CRSsNP and allergic rhinitis -only phenotypes. Setting Prospective controlled follow-up study. Participants Forty-two nonsmoking patients visiting tertiary care due to CRSsNP and 19 nonsmoking volunteer controls with allergic rhinitis filled a symptoms questionnaire and underwent nasal endoscopy off-seasonally. All CRSsNP patients underwent computed tomography scans of paranasal sinuses. All the allergic rhinitis control subjects and 14 of the CRSsNP patients underwent sinus magnetic resonance imaging. Results Radiologic Lund–Mackay score, duration of symptoms, visual analogue scale scores of symptoms, and Sinonasal Outcome Test 22 were significantly higher in the CRSsNP group compared to allergic rhinitis control group. These factors also correlated in part with each other. Endoscopic score did not correlate with other factors, nor did it differ between CRSsNP and allergic rhinitis groups. The highest area under curve value was demonstrated for visual analogue scale score of facial pain/pressure (0.93) and score ≥4/10 showed 60% sensitivity and 95% specificity for detecting CRSsNP group ( P < .001). Radiologic sign of obstructed osteomeatal complex showed 100% specificity and 38% sensitivity for detecting CRSsNP group ( P < .001). Conclusions CRSsNP phenotype could be primarily distinguished from allergic rhinitis by higher facial pain/pressure score and secondarily by radiologic sings of obstructed ostiomeatal complex and higher Lund–Mackay score. Endoscopic score has limited value in distinguishing CRSsNP from allergic rhinitis.


2018 ◽  
Vol 15 (6) ◽  
pp. 79-88
Author(s):  
N M Nenasheva ◽  
E P Terekhova ◽  
O S Bodnya ◽  
O V Sebekina

Allergic rhinitis (AR) is the most common form of rhinitis and the most common allergic disease in children and adults. Numerous clinical studies and daily practice indicate a pronounced negative effect of symptoms of AR on patients’ quality of life, their usual daily activity, cognitive functions, mood and sleep. The type and severity of individual symptoms can vary from patient to patient, and therapy should be directed to the overall control of the symptoms of AR. It is important to obtain reliable and comparable information regarding the severity of AR symptoms before, during and after the treatment, which can be assessed using a simple and accessible tool - a visual analogue scale (VAS). VAS validated for patients with AR allows to define a controlled, partially controlled and uncontrolled AR. The article proposes an algorithm for the treatment of AR, depending on the severity of the symptoms, assessed using VAS.


2017 ◽  
Vol 55 (1) ◽  
pp. 34-38 ◽  
Author(s):  
A Del Cuvillo ◽  
V Santos ◽  
J Montoro ◽  
J Bartra ◽  
I Davila ◽  
...  

Immunotherapy ◽  
2021 ◽  
Author(s):  
Peiyan Zheng ◽  
Xiaoqing Liu ◽  
Lili Lin ◽  
Huiqin Wu ◽  
Xiaoming Zhao ◽  
...  

Aim: To compare the efficacy of single- and double-species mite allergen immunotherapy. Materials and methods: An open, pseudo-randomized, controlled study was conducted (n = 125 allergic rhinitis patients). The primary end point involved the visual analogue scale. Secondary end points included a basophil activation test and serum specific IgE and IgG4 assays. Results: Visual analogue scale analysis indicated considerable reductions in both groups. Both treatments improved quality of life and induced sIgG4 antibody production. Basophil activation and serum IgE inhibition were not evident in either treatment. Neither treatment displayed an early stage immune synergistic effect on cross-allergens. Conclusions: Both treatments were effective against allergic rhinitis, and statistical differences were not observed. Future studies may require long-term, large-scale research.


2015 ◽  
Vol 5 (S4) ◽  
Author(s):  
Pär Stjärne ◽  
Victoria Strand ◽  
Kaj Theman ◽  
Hans Christian Kuhl ◽  
Anders Ehnhage

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