Oral and intravenous iron treatment in inflammatory bowel disease: Hematological response and quality of life improvement

2009 ◽  
Vol 15 (10) ◽  
pp. 1485-1491 ◽  
Author(s):  
Javier P. Gisbert ◽  
Fernando Bermejo ◽  
Ramón Pajares ◽  
Jose-Lázaro Pérez-Calle ◽  
María Rodríguez ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Inflammatory Bowel Disease ◽  
Bowel Disease ◽  
Intravenous Iron ◽  
Hematological Response ◽  
Iron Treatment ◽  
Life Improvement ◽  
Inflammatory Bowel

Su1238 Anemia and Inflammatory Bowel Disease: Effects of High-Dose Intravenous Iron Treatment on Hemoglobin, Activity Index and Quality of Life

2013 ◽  
Vol 144 (5) ◽  
pp. S-436 ◽  
Author(s):  
Judith Millastre ◽  
S. García-López ◽  
Eduardo Bajador ◽  
Maria Chaparro ◽  
Fernando Gomollon ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Inflammatory Bowel Disease ◽  
Bowel Disease ◽  
Activity Index ◽  
Intravenous Iron ◽  
High Dose ◽  
Iron Treatment ◽  
Inflammatory Bowel

scholarly journals The Effect of Intravenous Iron Treatment on Quality of Life in Inflammatory Bowel Disease Patients with Nonanemic Iron Deficiency

2015 ◽  
Vol 2015 ◽  
pp. 1-5 ◽  
Author(s):  
Cem Çekiç ◽  
Serkan İpek ◽  
Fatih Aslan ◽  
Zehra Akpınar ◽  
Mahmut Arabul ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Inflammatory Bowel Disease ◽  
Bowel Disease ◽  
Intravenous Iron ◽  
Iron Administration ◽  
Iron Treatment ◽  
Iron Deficient ◽  
Sf 36 ◽  
Inflammatory Bowel

Background.Iron deficiency is the prevalent complication of inflammatory bowel disease (IBD). Herein, we investigated the effect of intravenous iron treatment on quality of life (QoL) in nonanemic and iron deficient IBD patients.Methods.Eighty-five IBD patients were recruited for this study. The patients were intravenously administered 500 mg iron sucrose in the first week of the study. Hematologic parameters and QoL were evaluated before to iron treatment and during the 12th week of treatment. The Inflammatory Bowel Disease Questionnaire (IBDQ) and the Short Form-36 (SF-36) Health Survey were used to assess QoL.Results.Prior to intravenous iron administration, the IBDQ, SF-36 Physical Component Summary (PCS) and Mental Component Summary (MCS) scores were152.3±30.6,46.7±7.3, and45.7±9.8, respectively. In the 12th week of iron administration, those scores were162.3±25.5(P<0.001),49.3±6.4(P<0.001), and47.6±8.9(P=0.024), respectively, which were all significantly different from the scores prior to iron administration. The mean changes in the IBDQ scores for ulcerative colitis and Crohn’s disease were 8.7% and 3.0% (P=0.029), were 6.4% and 4.7% (P=0.562) for the SF-36 PCS, and were 4.6% and 3.2% (P=0.482) for the SF-36 MCS, respectively.Conclusion.Intravenous iron treatment may improve QoL in nonanemic, but iron deficient, IBD patients.

scholarly journals Gastroenterologist-Lead Management of Iron Deficiency Anemia in Inflammatory Bowel Disease Is Effective, Safe, and May Increase Quality of Life

2020 ◽  
Vol 2 (3) ◽  
Author(s):  
Christopher L Coe ◽  
Matthew H Meyers ◽  
Dawn B Beaulieu ◽  
Elizabeth Scoville ◽  
David A Schwartz ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Inflammatory Bowel Disease ◽  
Iron Deficiency ◽  
Iron Deficiency Anemia ◽  
Bowel Disease ◽  
Retrospective Chart Review ◽  
Intravenous Iron ◽  
Deficiency Anemia ◽  
Inflammatory Bowel

Abstract Background The effectiveness and safety of gastroenterologist (GI)-lead treatment of iron deficiency anemia (IDA) in inflammatory bowel disease (IBD) have not been well-studied. Methods A retrospective chart review of patients with IBD, IDA, and evidence of treatment with iron at a tertiary IBD center was conducted. Results In 351 patients, hemoglobin and quality of life scores increased significantly after treatment with iron. Twelve of 341 patients treated with intravenous iron had an adverse effect. Twenty-seven patients required a hematology referral. Conclusion GIs should consider treating patients with IBD and IDA with intravenous iron as it is safe and effective.

Intravenous Iron Replacement Improves Quality of Life in Hypoferritinemic Inflammatory Bowel Disease Patients with and without Anemia

2017 ◽  
Vol 35 (5) ◽  
pp. 444-448 ◽  
Author(s):  
Elena Eliadou ◽  
Gregory Kini ◽  
Judy Huang ◽  
Amy Champion ◽  
Stephen James Inns
Keyword(s):  
Quality Of Life ◽  
Inflammatory Bowel Disease ◽  
Bowel Disease ◽  
Intravenous Iron ◽  
Iron Therapy ◽  
Physical Component Score ◽  
Component Score ◽  
Inflammatory Bowel ◽  
Iron Replacement

Background: No study has compared changes in quality of life (QoL) following iron therapy between anemic and non-anemic, hypoferritinemic patients. This study compares the impact of parenteral iron replacement on QoL in inflammatory bowel disease (IBD) patients with anemia, or in those with hypoferritinemia alone. Methods: Consecutive IBD patients diagnosed with anemia or hypoferritinemia were enrolled. IBD questionnaire (IBDQ) and 36-Item Short Form Survey (SF36) at diagnosis and 6 weeks post treatment were measured. Results: Ten patients with anemia and 13 with hypoferritinemia were treated with intravenous iron polymaltose. Across all patients, there was a significant improvement in median SF36 mental component score by 8.5 (p = 0.004) and median IBDQ by 12 (p = 0.02). There was a trend towards improved median SF36 physical component score by 3.2 (p = 0.6). These changes were not significantly different when comparing anemic with hypoferritinemic patients. In IBDQ, there was a trend toward greater improvement in hypoferritinemic vs. anemic patients (20 vs. 1.5, p = 0.31). Conclusions: This is the first study to show that improvements in QoL in hypoferritinemic patients are similar to those with anemia. Based on these results, patients with IBD should be offered the option of iron therapy when they are found to be hypoferritinemic, even in the absence of anemia.

Psychosocial Aspects of Quality of Life for Inflammatory Bowel Disease

2006 ◽  
Author(s):  
Carmen E. Curtis ◽  
Gary W. Harper ◽  
Leonard A. Jason ◽  
Brigida Hernandez
Keyword(s):  
Quality Of Life ◽  
Inflammatory Bowel Disease ◽  
Bowel Disease ◽  
Psychosocial Aspects ◽  
Inflammatory Bowel
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