Next-day residual effects of gaboxadol and flurazepam administered at bedtime: a randomized double-blind study in healthy elderly subjects

2009 ◽  
Vol 24 (1) ◽  
pp. 61-71 ◽  
Author(s):  
Julia Boyle ◽  
Dennis Wolford ◽  
Cynthia Gargano ◽  
Jacqueline McCrea ◽  
Corinne Cummings ◽  
...  
Keyword(s):  
Blind Study ◽  
Residual Effects ◽  
Elderly Subjects ◽  
Double Blind Study ◽  
Double Blind ◽  
Healthy Elderly ◽  
Healthy Elderly Subjects

scholarly journals Residual effects of eszopiclone and placebo in healthy elderly subjects: a randomized double-blind study

2017 ◽  
Vol 15 (3) ◽  
pp. 235-241 ◽  
Author(s):  
Jun Takahashi ◽  
Takashi Kanbayashi ◽  
Sachiko Ito Uemura ◽  
Youhei Sagawa ◽  
Kou Tsutsui ◽  
...  
Keyword(s):  
Blind Study ◽  
Residual Effects ◽  
Elderly Subjects ◽  
Double Blind Study ◽  
Double Blind ◽  
Healthy Elderly ◽  
Healthy Elderly Subjects

scholarly journals 0358 RESIDUAL EFFECTS OF ESZOPICLONE AND PLACEBO IN HEALTHY ELDERLY SUBJECTS, A RANDOMIZED DOUBLE BLIND STUDY

SLEEP ◽  
2017 ◽  
Vol 40 (suppl_1) ◽  
pp. A133-A133
Author(s):  
J Takahahsi ◽  
K Takashi ◽  
S Ito Uemura ◽  
Y Sagawa ◽  
K Tsutsui ◽  
...  
Keyword(s):  
Blind Study ◽  
Residual Effects ◽  
Elderly Subjects ◽  
Double Blind Study ◽  
Double Blind ◽  
Healthy Elderly ◽  
Healthy Elderly Subjects

scholarly journals 0348 RESIDUAL EFFECTS OF SUVOREXANT, ZOLPIDEM AND RAMELTEON IN HEALTHY ELDERLY SUBJECTS: A RANDOMIZED DOUBLE-BLIND STUDY

SLEEP ◽  
2017 ◽  
Vol 40 (suppl_1) ◽  
pp. A130-A130
Author(s):  
SU Ito ◽  
T Kanbayashi ◽  
A Ito ◽  
Y Kimoto ◽  
T Ono ◽  
...  
Keyword(s):  
Blind Study ◽  
Residual Effects ◽  
Elderly Subjects ◽  
Double Blind Study ◽  
Double Blind ◽  
Healthy Elderly ◽  
Healthy Elderly Subjects

Residual effects of zolpidem, triazolam, rilmazafone and placebo in healthy elderly subjects: a randomized double-blind study

2015 ◽  
Vol 16 (11) ◽  
pp. 1395-1402 ◽  
Author(s):  
Sachiko Ito Uemura ◽  
Takashi Kanbayashi ◽  
Masahiko Wakasa ◽  
Masahiro Satake ◽  
Wakako Ito ◽  
...  
Keyword(s):  
Blind Study ◽  
Residual Effects ◽  
Elderly Subjects ◽  
Double Blind Study ◽  
Double Blind ◽  
Healthy Elderly ◽  
Healthy Elderly Subjects

scholarly journals Influence of a combination ofLactobacillus acidophilusNCFM and lactitol on healthy elderly: intestinal and immune parameters

2008 ◽  
Vol 101 (3) ◽  
pp. 367-375 ◽  
Author(s):  
Arthur C. Ouwehand ◽  
Kirsti Tiihonen ◽  
Markku Saarinen ◽  
Heli Putaala ◽  
Nina Rautonen
Keyword(s):  
Intestinal Microbiota ◽  
Bowel Function ◽  
Elderly Subjects ◽  
Immune Markers ◽  
Double Blind ◽  
Healthy Elderly ◽  
Immune Parameters ◽  
Age Related ◽  
Over Time ◽  
Healthy Elderly Subjects

With increasing age, a number of physiological changes take place which are reflected in immune and bowel function. These changes may relate to the commonly assumed age-related changes in intestinal microbiota; most noticeably a reduction in bifidobacteria. The current study aimed at modifying the intestinal microbiota with a potential synbiotic on selected immune and microbiota markers. Healthy elderly subjects were randomised to consume during 2 weeks either a placebo (sucrose) or a combination of lactitol andLactobacillus acidophilusNCFM twice daily in a double-blind parallel trial. After the intervention, stool frequency was higher in the synbiotic group than in the placebo group and a significant increase in faecalL. acidophilusNCFM levels was observed in the synbiotic group, after baseline correction. In contrast to the generally held opinion, the study subjects had faecalBifidobacteriumlevels that were similar to those reported in healthy young adults. These levels were, nevertheless, significantly increased by the intervention. Levels of SCFA were not changed significantly. Of the measured immune markers, PGE2levels were different between treatments and IgA levels changed over time. These changes were modest which may relate to the fact that the volunteers were healthy. Spermidine levels changed over time which may suggest an improved mucosal integrity and intestinal motility. The results suggest that consumption of lactitol combined withL. acidophilusNCFM twice daily may improve some markers of the intestinal microbiota composition and mucosal functions.

scholarly journals A RANDOMISED DOUBLE-BLIND CLINICAL STUDY TO EVALUATE AND COMPARE THE EFFECTS OF VRIDDADARU RASAYANA WITH BHARGAVAPROKTA RASAYANA ON AGEING IN APPARENTLY HEALTHY ELDERLY SUBJECTS

2020 ◽  
pp. 13-23
Author(s):  
Manasa H P ◽  
Yogeesha Acharya ◽  
Sandesh Kumar
Keyword(s):  
Quality Of Life ◽  
Clinical Study ◽  
The Elderly ◽  
Elderly Subjects ◽  
Double Blind ◽  
General Body ◽  
Healthy Elderly ◽  
Healthy Elderly Subjects ◽  
Apparently Healthy

According to estimation, India currently has 6.7% over 65 years of age, which is expected to increase to 20% by the year 2050. As growing old is a part of the life cycle, the effect of time is bound to happen and is unavoidable. The Kalajajara is a Swabhavika vyadhi, wherein, it is clearly mentioned that Swabhava balapravritta vyadhis being Yapya, can be managed through Bhojana, Paana, and Rasayana. Vriddadaru Rasayana is one such Rasayana mentioned in Gadanigraha especially for the elderly to promote healthy ageing and helping to prevent old age problems. Aims and objectives: To assess the effect of Vriddadaru Rasayana in improving the general body health and quality of life in the apparently healthy elderly subjects. Methodology– A Randomized double blind clinical study where 20 healthy elderly subjects were administered with Vriddadaru Rasayana for a period of 12 weeks. Observations and Results- Vriddadaru rasayana showed improvement in Ayurvedic parameters like Twakparushata, Slataasti, Slata sandhi, Utasahahani and Parakramahani but when compared with regard to objective parameters Vriddadaru rasayana showed significant values in DHEAS levels and 6MWT. Conclusion: Vriddadaru does Vatashamana, balancing the Doshas, increasing the Utsaha and Parakrama and helps in improving the Agni thus helping in Dhatuposhana in the elderly.

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