Dextro-amphetamine increases phosphoinositol cycle activity in volunteers: an MRS study

2002 ◽  
Vol 17 (8) ◽  
pp. 425-429 ◽  
Author(s):  
Peter H. Silverstone ◽  
Tina O'Donnell ◽  
Michele Ulrich ◽  
Sheila Asghar ◽  
Christopher C. Hanstock
Keyword(s):  
Dextro Amphetamine

Effects of Oxygen and Dextro-Amphetamine Upon Work Decrement

1957 ◽  
Author(s):  
George T. Hauty ◽  
Robert B. Payne ◽  
Robert O. Bauer
Keyword(s):  
Dextro Amphetamine

HYPERKALEMIC FAMILIAL PERIODIC PARALYSIS

PEDIATRICS ◽  
1959 ◽  
Vol 24 (5) ◽  
pp. 761-773
Author(s):  
T. J. Egan ◽  
R. Klein
Keyword(s):  
Urinary Excretion ◽  
Opposite Direction ◽  
Recovery Period ◽  
Acute Attack ◽  
Periodic Paralysis ◽  
Hospitalized Patients ◽  
High Concentration ◽  
Definite Improvement ◽  
Dextro Amphetamine ◽  
Amphetamine Sulfate

The clinical histories of three families are described, who have a variant of familial periodic paralysis characterized by high concentration of potassium during paralytic episodes unassociated with diminished urinary excretion of potassium. Data are presented concerning five hospitalized patients from the three families. The data indicate that the rise in concentration of potassium in serum results from a shift of potassium into the extracellular phase. During the recovery period potassium travels in the opposite direction. The administration of glucagon or epinephrine during an acute attack terminated the attack promptly. The administration of 10 to 15 mg of dextro-amphetamine sulfate daily in Spansule® form effectively controlled symptoms in two patients, and resulted in definite improvement in a third patient, treated for periods varying from 3 to 7 months.

The Effects of Meprobamate on the Performance of a Five-Choice Serial Reaction Time Task

1961 ◽  
Vol 107 (448) ◽  
pp. 590-602 ◽  
Author(s):  
G. S. Claridge
Keyword(s):  
Motor Performance ◽  
Conditioned Inhibition ◽  
Reaction Time Task ◽  
Serial Reaction Time Task ◽  
Drug Action ◽  
Cortical Inhibition ◽  
Stimulant Drugs ◽  
Pursuit Rotor ◽  
Serial Reaction ◽  
Dextro Amphetamine

The theoretical framework developed by Eysenck (1955) to account for individual differences in motor and other types of performance has, as its main postulate, the statement that extraverts are characterized by high rates and introverts by low rates of inhibitory growth. An extension of this framework (1957) has allowed a link to be made between personality theory and the theory of drug action, since it has been proposed that depressant drugs increase cortical inhibition and so produce extraverted behaviour patterns, while the opposite is true of stimulant drugs. A test of this postulate by Eysenck, Casey and Trouton (1957) suggested that it was essentially confirmed when applied to motor performance. Dextro-amphetamine sulphate was found to improve and sodium amylobarbitone to depress pursuit rotor performance at all stages of practice. It was concluded that the effect of sodium amylobarbitone was to increase the two inhibitory factors recognized by Hullian learning theory, viz. conditioned inhibition (SIR) and reactive inhibition (IR).

The Effects of Anorexic Doses of dextro-Amphetamine on the Ventromedial-Hypothalamic Hyperphagic Rat

1973 ◽  
Vol 51 (5) ◽  
pp. 354-359 ◽  
Author(s):  
Thomas B. Wishart ◽  
Elwood K. Walls
Keyword(s):  
Recovery Period ◽  
Ventromedial Hypothalamus ◽  
Weight Changes ◽  
Control Groups ◽  
Response Curves ◽  
Body Weight Changes ◽  
Rapid Weight Gain ◽  
Electrolytic Lesions ◽  
Dextro Amphetamine ◽  
And Control

Rats were made hyperphagic by the production of electrolytic lesions in the ventromedial hypothalamus. Following a recovery period during which a rapid weight gain was observed, d-amphetamine was administered intraperitoneally in various dosages, and food intakes, water intakes, and body weight changes were measured after a 3 h feeding period. A dosage of 0.2 mg/kg d-amphetamine had no observable effect. Increasing the dosage to 0.5 or 1.0 mg/kg, however, significantly depressed food and water intakes, and resulted in reduced weight gains in control and experimental animals. Furthermore, the dose–response curves for both experimental and control groups were similar, indicating that d-amphetamine has the same effect in the hyperphagic rat as in the control. It is concluded that amphetamine anorexia is not mediated by the ventromedial hypothalamus.

The Analgesic Effect of Morphine Alone and in Combination with Dextro-Amphetamine.

1944 ◽  
Vol 55 (4) ◽  
pp. 248-250 ◽  
Author(s):  
F. R. Goetzl ◽  
D. Y. Burrill ◽  
A. C. Ivy
Keyword(s):  
Analgesic Effect ◽  
Dextro Amphetamine
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