scholarly journals Rimonabant effects on anxiety induced by simulated public speaking in healthy humans: a preliminary report

2013 ◽  
Vol 29 (1) ◽  
pp. 94-99 ◽  
Author(s):  
Mateus M. Bergamaschi ◽  
Regina H. C. Queiroz ◽  
Marcos H. N. Chagas ◽  
Ila M. P. Linares ◽  
Kátia C. Arrais ◽  
...  
Keyword(s):  
Preliminary Report ◽  
Public Speaking ◽  
Healthy Humans ◽  
Simulated Public Speaking

Effects of Gabapentin on Anxiety Induced by Simulated Public Speaking

2003 ◽  
Vol 17 (2) ◽  
pp. 184-188 ◽  
Author(s):  
Joao Quevedo ◽  
Tatiana Barichello ◽  
Ivan Izquierdo ◽  
Monica R. M. Vianna ◽  
Fernanda de-Paris ◽  
...  
Keyword(s):  
Public Speaking ◽  
Simulated Public Speaking

scholarly journals Cannabidiol presents an inverted U-shaped dose-response curve in the simulated public speaking test

2016 ◽  
Vol 26 ◽  
pp. S617 ◽  
Author(s):  
I. Linares ◽  
A.W. Zuardi ◽  
L.C.G. Pereira ◽  
R.H.C. Queiroz ◽  
R. Mechoulam ◽  
...  
Keyword(s):  
Dose Response ◽  
Response Curve ◽  
Public Speaking ◽  
Dose Response Curve ◽  
Speaking Test ◽  
Simulated Public Speaking

scholarly journals Human experimental anxiety: actual public speaking induces more intense physiological responses than simulated public speaking

2013 ◽  
Vol 35 (3) ◽  
pp. 248-253 ◽  
Author(s):  
Antonio Waldo Zuardi ◽  
José Alexandre de Souza Crippa ◽  
Jaime Eduardo Cecílio Hallak ◽  
Ricardo Gorayeb
Keyword(s):  
Public Speaking ◽  
Physiological Responses ◽  
Simulated Public Speaking

scholarly journals Cannabidiol presents an inverted U-shaped dose-response curve in a simulated public speaking test

2019 ◽  
Vol 41 (1) ◽  
pp. 9-14 ◽  
Author(s):  
Ila M. Linares ◽  
Antonio W. Zuardi ◽  
Luis C. Pereira ◽  
Regina H. Queiroz ◽  
Raphael Mechoulam ◽  
...  
Keyword(s):  
Dose Response ◽  
Response Curve ◽  
Public Speaking ◽  
Dose Response Curve ◽  
Speaking Test ◽  
Simulated Public Speaking

Anxiety and salivary cortisol in symptomatic and nonsymptomatic panic patients and healthy volunteers performing simulated public speaking

2005 ◽  
Vol 133 (2-3) ◽  
pp. 239-252 ◽  
Author(s):  
Cybele Garcia-Leal ◽  
Alexandre C.B.V. Parente ◽  
Cristina M. Del-Ben ◽  
Francisco S. Guimarães ◽  
Ayrton Custódio Moreira ◽  
...  
Keyword(s):  
Healthy Volunteers ◽  
Salivary Cortisol ◽  
Public Speaking ◽  
Simulated Public Speaking

Effects of acute cannabidiol administration on anxiety and tremors induced by a Simulated Public Speaking Test in patients with Parkinson’s disease

2020 ◽  
Vol 34 (2) ◽  
pp. 189-196 ◽  
Author(s):  
Stephanie Martins de Faria ◽  
Daiene de Morais Fabrício ◽  
Vitor Tumas ◽  
Paula Costa Castro ◽  
Moacir Antonelli Ponti ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Repeated Measures ◽  
Public Speaking ◽  
Cannabis Sativa ◽  
Signs And Symptoms ◽  
Systemic Blood Pressure ◽  
Speaking Test ◽  
Double Blinded ◽  
Simulated Public Speaking

Background: Cannabidiol (CBD) is one of the main components of Cannabis sativa and has anxiolytic properties, but no study has been conducted to evaluate the effects of CBD on anxiety signs and symptoms in patients with Parkinson’s disease (PD). This study aimed to evaluate the impacts of acute CBD administration at a dose of 300 mg on anxiety measures and tremors induced by a Simulated Public Speaking Test (SPST) in individuals with PD. Methods: A randomised, double-blinded, placebo-controlled, crossover clinical trial was conducted. A total of 24 individuals with PD were included and underwent two experimental sessions within a 15-day interval. After taking CBD or a placebo, participants underwent the SPST. During the test, the following data were collected: heart rate, systemic blood pressure and tremor frequency and amplitude. In addition, the Visual Analog Mood Scales (VAMS) and Self-Statements during Public Speaking Scale were applied. Statistical analysis was performed by repeated-measures analysis of variance (ANOVA) while considering the drug, SPST phase and interactions between these variables. Results: There were statistically significant differences in the VAMS anxiety factor for the drug; CBD attenuated the anxiety experimentally induced by the SPST. Repeated-measures ANOVA showed significant differences in the drug for the variable related to tremor amplitude as recorded by the accelerometer. Conclusion: Acute CBD administration at a dose of 300 mg decreased anxiety in patients with PD, and there was also decreased tremor amplitude in an anxiogenic situation.

scholarly journals Escitalopram Prolonged Fear Induced by Simulated Public Speaking and Released Hypothalamic-Pituitary-Adrenal Axis Activation

2009 ◽  
Vol 24 (S1) ◽  
pp. 1-1
Author(s):  
C. Garcia-Leal ◽  
C.M. Del-Ben ◽  
F.M. Leal ◽  
F.G. Graeff ◽  
F.S. Guimarães
Keyword(s):  
Selective Serotonin Reuptake Inhibitors ◽  
Public Speaking ◽  
Selective Serotonin ◽  
Neural Systems ◽  
Double Blind ◽  
Enhancing Effect ◽  
Randomized Design ◽  
Pituitary Adrenal Axis ◽  
Serotonin Selective Reuptake Inhibitor ◽  
Simulated Public Speaking

Simulated Public Speaking (SPS) test is sensitive to drugs that interfere with serotonin-mediated neurotransmission and is supposed to recruit neural systems involved in panic disorder. The study was aimed at evaluating the effects of escitalopram, the most selective serotonin selective reuptake inhibitor available, in SPS. Healthy males received, in a double-blind, randomized design, placebo (n=12), 10 (n=17) or 20 (n=14) mg of escitalopram two hours before the test. Behavioural, autonomic and neuroendocrine measures were assessed. Both doses of escitalopram did not produce any effect before or during the speech, but prolonged the fear induced by SPS. The test itself did not significantly change cortisol and prolactin levels, but under the higher dose of escitalopram, cortisol and prolactin increased immediately after SPS. This fear-enhancing effect of escitalopram agrees with previously reported results with less selective serotonin reuptake inhibitors and the receptor antagonist ritanserin, indicating that serotonin inhibits speaking fear.

scholarly journals Cannabidiol Reduces the Anxiety Induced by Simulated Public Speaking in Treatment-Naïve Social Phobia Patients

2011 ◽  
Vol 36 (6) ◽  
pp. 1219-1226 ◽  
Author(s):  
Mateus M Bergamaschi ◽  
Regina Helena Costa Queiroz ◽  
Marcos Hortes Nisihara Chagas ◽  
Danielle Chaves Gomes de Oliveira ◽  
Bruno Spinosa De Martinis ◽  
...  
Keyword(s):  
Social Phobia ◽  
Public Speaking ◽  
Treatment Naïve ◽  
Simulated Public Speaking
Sign in / Sign up

Export Citation Format

Share Document