scholarly journals The role of translation elongation factor eEF1 subunits in neurodevelopmental disorders

2018 ◽  
Vol 40 (2) ◽  
pp. 131-141 ◽  
Author(s):  
Fiona McLachlan ◽  
Anna Martinez Sires ◽  
Catherine M. Abbott
Keyword(s):  
Neurodevelopmental Disorders ◽  
Elongation Factor ◽  
Translation Elongation Factor ◽  
Translation Elongation

scholarly journals In vivo characterization of the role of tissue‐specific translation elongation factor 1 A 2 in protein synthesis reveals insights into muscle atrophy

FEBS Journal ◽  
2013 ◽  
Vol 280 (24) ◽  
pp. 6528-6540 ◽  
Author(s):  
Jennifer Doig ◽  
Lowri A. Griffiths ◽  
David Peberdy ◽  
Permphan Dharmasaroja ◽  
Maria Vera ◽  
...  
Keyword(s):  
Protein Synthesis ◽  
Muscle Atrophy ◽  
Elongation Factor ◽  
Translation Elongation Factor ◽  
Translation Elongation ◽  
In Vivo Characterization ◽  
Elongation Factor 1

scholarly journals The role of translation elongation factor eEF1A in intracellular alkalinization-induced tumor cell growth

2009 ◽  
Vol 89 (8) ◽  
pp. 867-874 ◽  
Author(s):  
Juno Kim ◽  
Wan Namkung ◽  
Jae Seok Yoon ◽  
Min Jae Jo ◽  
Sung Hee Lee ◽  
...  
Keyword(s):  
Cell Growth ◽  
Tumor Cell ◽  
Elongation Factor ◽  
Tumor Cell Growth ◽  
Translation Elongation Factor ◽  
Translation Elongation ◽  
Intracellular Alkalinization

The role of Snu114p during pre-mRNA splicing

2008 ◽  
Vol 36 (3) ◽  
pp. 551-553 ◽  
Author(s):  
Lily Novak Frazer ◽  
Verity Nancollis ◽  
Raymond T. O'Keefe
Keyword(s):  
Gene Expression ◽  
Protein Complex ◽  
Current Knowledge ◽  
Elongation Factor ◽  
Mrna Splicing ◽  
Splice Sites ◽  
Translation Elongation Factor ◽  
Translation Elongation ◽  
Essential Step

Pre-mRNA splicing is an essential step in gene expression where intron regions are removed and coding exon sequences are joined to form an mRNA for translation. Splicing is catalysed by an RNA–protein complex called the spliceosome. A number of spliceosome proteins are required for assembly and remodelling of the spliceosome with pre-mRNA to orient the splice sites correctly and catalyse the two steps of splicing. The spliceosome protein Snu114p is a GTPase that is related to the translation elongation factor EF-2. Snu114p plays a key role in spliceosome remodelling. In the present review, we briefly summarize the current knowledge of the function of Snu114p in pre-mRNA splicing and the role it plays in spliceosome dynamics.

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