Interleukin-1B (IL1B) and interleukin-6 (IL6) gene polymorphisms are associated with risk of chronic lymphocytic leukaemia

2008 ◽  
Vol 26 (2) ◽  
pp. 98-103 ◽  
Author(s):  
Maria G. Ennas ◽  
Patrick S. Moore ◽  
Mariagrazia Zucca ◽  
Emanuele Angelucci ◽  
Maria G. Cabras ◽  
...  
Keyword(s):  
Chronic Lymphocytic Leukaemia ◽  
Interleukin 6 ◽  
Gene Polymorphisms ◽  
Lymphocytic Leukaemia ◽  
Il6 Gene

Interleukin-6 Inhibits Apoptosis and Tumour Necrosis Factor Induced Proliferation of B-Chronic Lymphocytic Leukaemia

1996 ◽  
Vol 22 (1-2) ◽  
pp. 83-90 ◽  
Author(s):  
Joyce E. Reittie ◽  
Kwee L. Yong ◽  
Panayiotis Panayiotidis ◽  
A. Victor Hoffbrand
Keyword(s):  
Chronic Lymphocytic Leukaemia ◽  
Tumour Necrosis Factor ◽  
Interleukin 6 ◽  
Tumour Necrosis ◽  
Lymphocytic Leukaemia ◽  
Necrosis Factor

2.21 Autocrine Interleukin-6 Production Correlated with Survival of Chronic Lymphocytic Leukaemia Cells

2011 ◽  
Vol 11 ◽  
pp. S172 ◽  
Author(s):  
Fengting Liu ◽  
Li Jia ◽  
Tim Farren ◽  
John Gribben ◽  
Samir Agrawal
Keyword(s):  
Chronic Lymphocytic Leukaemia ◽  
Interleukin 6 ◽  
Lymphocytic Leukaemia

Autologous T lymphocytes recognize the tumour-derived immunoglobulin VH-CDR3 region in patients with B-cell chronic lymphocytic leukaemia

2000 ◽  
Vol 111 (1) ◽  
pp. 230-238 ◽  
Author(s):  
Mohammad Reza Rezvany ◽  
Mahmood Jeddi-Tehrani ◽  
Hodjattallah Rabbani ◽  
Ulla Ruden ◽  
Lennart Hammarstrom ◽  
...  
Keyword(s):  
T Lymphocytes ◽  
Chronic Lymphocytic Leukaemia ◽  
B Cell ◽  
Lymphocytic Leukaemia ◽  
Cell Chronic Lymphocytic Leukaemia ◽  
Cdr3 Region

Pharmacokinetics of Chlorambucil in Patients with Chronic Lymphocytic Leukaemia: Comparison of Different Days, Cycles and Doses

2000 ◽  
Vol 87 (5) ◽  
pp. 223-228 ◽  
Author(s):  
Raija Silvennoinen ◽  
Kimmo Malminiemi ◽  
Outi Malminiemi ◽  
Erkki Seppala ◽  
Juhani Vilpo
Keyword(s):  
Chronic Lymphocytic Leukaemia ◽  
Lymphocytic Leukaemia

The Local Sanarelli-Shwartzman Phenomenon in Rats Induced by Human Leukaemic Cells

1973 ◽  
Vol 29 (02) ◽  
pp. 353-362
Author(s):  
J Lisiewicz ◽  
A Pituch ◽  
J. A Litwin
Keyword(s):  
Chronic Lymphocytic Leukaemia ◽  
Intravenous Injection ◽  
Peripheral Blood ◽  
Lymphocytic Leukaemia ◽  
Acute Myeloblastic Leukaemia ◽  
Demarcation Line ◽  
E Coli ◽  
Leukaemic Cells ◽  
Shwartzman Phenomenon

SummaryThe local Sanarelli-Shwartzman phenomenon (SSP-L) in the skin of 30 rats was induced by an intr a cutaneous sensitizing injection of leukaemic leucocytes isolated from the peripheral blood of patients with chronic lymphocytic leukaemia (CLL), acute myeloblastic leukaemia (AL) and chronic granulocytic leukaemia (CGL) and challenged by an intravenous injection of 100(μ of E. coli endotoxin. SSP-L was observed in 7 rats after injection of CLL lymphocytes and in 6 and 2 rats after AL myeloblasts and the CGL granulocytes, respectively. The lesions in the skin after AL myeloblasts appeared in a shorter time and were of longer duration compared with those observed after CLL lymphocytes and CGL granulocytes. Histologically, the lesions consisted of areas of destruction in the superficial layers of the skin ; the demarcation line showed the presence of neutrophils, macrophages and erythrocytes. Haemorrhages and fibrin deposits near the demarcation line were larger after injection of CLL lymphocytes and AL myeloblasts than after CGL granulocytes. The possible role of leucocyte procoagulative substances in the differences observed have been discussed.

Sign in / Sign up

Export Citation Format

Share Document