scholarly journals PROGNOSTIC ROLE OF LESION DISSEMINATION FEATURE (DMAX) CALCULATED ON BASELINE PET/CT IN HODGKIN LYMPHOMA

2021 ◽  
Vol 39 (S2) ◽  
Author(s):  
R Durmo ◽  
A Ségolèn Cottereau ◽  
L Rebaud ◽  
C Nioche ◽  
A Ruffini ◽  
...  
2016 ◽  
Vol 30 (8) ◽  
pp. 588-592 ◽  
Author(s):  
Salvatore Annunziata ◽  
Annarosa Cuccaro ◽  
Maria Lucia Calcagni ◽  
Stefan Hohaus ◽  
Alessandro Giordano ◽  
...  

2021 ◽  
Vol 39 (S2) ◽  
Author(s):  
G. M. Assanto ◽  
R. Agrippino ◽  
G. Lapietra ◽  
M. L. De Luca ◽  
A. Chiaravalloti ◽  
...  

2020 ◽  
Vol 61 (13) ◽  
pp. 3209-3216
Author(s):  
Domenico Albano ◽  
Angelica Mazzoletti ◽  
Vittorio Ruggero Zilioli ◽  
Cristina Muzi ◽  
Lara Crucitti ◽  
...  

Cancers ◽  
2021 ◽  
Vol 13 (16) ◽  
pp. 3952
Author(s):  
Andrea Gallamini ◽  
Michał Kurlapski ◽  
Jan Maciej Zaucha

In the present review, the authors report the published evidence on the use of functional imaging with FDG-PET/CT in assessing the final response to treatment in Hodgkin lymphoma. Despite a very high overall Negative Predictive Value of post-chemotherapy PET on treatment outcome ranging from 94% to 86%, according to different treatment intensity, the Positive Predicting Value proved much lower (40–25%). In the present review the Authors discuss the role of PET to guide consolidation RT over a RM after different chemotherapy regimens, both in early and in advanced-stage disease. A particular emphasis is dedicated to the peculiar issue of the qualitative versus semi-quantitative methods for End-of Therapy PET scan interpretation. A short hint will be given on the role of FDG-PET to assess the treatment outcome after immune checkpoint inhibitors.


Endocrines ◽  
2021 ◽  
Vol 2 (1) ◽  
pp. 28-36
Author(s):  
Ludovica Magi ◽  
Maria Rinzivillo ◽  
Francesco Panzuto

Owing to the rarity and the biological and clinical heterogeneity of gastroenteropancreatic neuroendocrine neoplasia (GEP NEN), the management of these patients may be challenging for physicians. This review highlights the specific features of GEP NEN with particular attention on the role of Ki67 heterogeneity, the potential prognostic role of novel radiological techniques, and the clinical usefulness of functional imaging, including 68Ga-DOTA-SST PET/CT and 18F-FDG PET/CT. Understanding these specific features may help to plan proper and tailored follow-up programs and therapeutic approaches.


Cancers ◽  
2021 ◽  
Vol 13 (12) ◽  
pp. 2876
Author(s):  
Giovanni Manfredi Assanto ◽  
Giulia Ciotti ◽  
Mattia Brescini ◽  
Maria Lucia De Luca ◽  
Giorgia Annechini ◽  
...  

Background: Despite that the unfavorable prognostic role of a high Total Metabolic Tumor Volume (TMTV) in Follicular Lymphoma has been demonstrated, the role of SUVmax alone at baseline PET/CT could have a different prognostic role. Patients and Methods: We performed a retrospective observational monocentric cohort study. All patients affected by FL who underwent a basal PET/CT were included. Two subgroups were identified and compared in terms of PFS and OS: (A) Basal SUVmax ≤ 6; and (B) Basal SUVmax > 6. Results: Ninety-four patients were included, 34 in group A (36.2%) and 60 in group B (63.8%). The PFS at two years was comparable in the two groups (97%). The five-year PFS was 73.5% for group A and 95% for group B (p 0.005). The five-year PFS in the whole cohort was 87.5%. A clear advantage was confirmed in group A in the absence of other risk factors. Patients with SUVmax ≤ 6 and no risk factors showed a 5-year PFS of 73% against 83% for patients with SUVmax > 6 and at least two risk factors. Conclusion: A high FDG uptake favorably correlated with PFS. A low basal SUVmax reflected a higher rate of late relapse requiring a prolonged follow-up. The basal SUVmax is an approachable parameter with prognostic implications.


2018 ◽  
Vol 22 (5) ◽  
pp. 393-400 ◽  
Author(s):  
A. Berriolo-Riedinger ◽  
S. Becker ◽  
O. Casasnovas ◽  
T. Vander Borght ◽  
V. Édeline

2018 ◽  
Vol 37 (1) ◽  
pp. 39-46 ◽  
Author(s):  
Domenico Albano ◽  
Giovanni Bosio ◽  
Luca Camoni ◽  
Mirko Farina ◽  
Alessandro Re ◽  
...  

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