A Novel Catalyst-Free One-Pot Synthesis of Some New N-(α-Hydroxybenzyl)formamides by Treatment of 2,2-Dichloroaziridines with Dimethyl Sulfoxide and Water under Neutral Conditions

2012 ◽  
Vol 95 (7) ◽  
pp. 1102-1107 ◽  
Author(s):  
Hossein Naeimi ◽  
Khadijeh Rabiei
Keyword(s):  
Dimethyl Sulfoxide ◽  
One Pot ◽  
Catalyst Free ◽  
One Pot Synthesis ◽  
Novel Catalyst ◽  
Neutral Conditions

Novel One-pot Synthesis of Pyranocarbazole Derivatives via an Isocyanide-based Three-component Reaction

2020 ◽  
Vol 17 ◽  
Author(s):  
Visarapu Malathi ◽  
Pedavenkatagari Narayana Reddy ◽  
Pannala Padmaja
Keyword(s):  
Efficient Method ◽  
Atom Economy ◽  
Reaction Conditions ◽  
One Pot ◽  
Catalyst Free ◽  
One Pot Synthesis ◽  
Three Component Reaction ◽  
High Yields

Abstract:: An efficient method has been developed for the synthesis of new pyrano[3,2-c] and pyrano[3,2-a]carbazole de-rivatives via a three component reaction of 4-hydroxycarbazole or 2-hydroxycarbazole, isocyanides, and dialkylacetylenedi-carboxylates. Noteworthy features of this protocol include mild reaction conditions, catalyst-free, high atom-economy and high yields.

Facile Approach to Geminal Heterodihalogenation. One-Pot Synthesis of α-Bromo-α-Chloro Ketones

Synlett ◽  
2020 ◽  
Vol 31 (14) ◽  
pp. 1430-1434
Author(s):  
Ming Bian ◽  
Jin-feng Zhou ◽  
Dong-min Tang
Keyword(s):  
Drug Discovery ◽  
Dimethyl Sulfoxide ◽  
Functional Groups ◽  
Methyl Ketones ◽  
One Pot ◽  
One Pot Synthesis ◽  
Operational Simplicity

An efficient and practical protocol for the geminal heterodihalogenation of methyl ketones by using readily available dimethyl sulfoxide and a combination of HCl and HBr is reported. Control experiments suggested that the acidity of the solution, as well as the oxidizing ability and nucleophilicity of the dimethyl sulfoxide might work cooperatively in ensuring the success of the tandem substitution. Its operational simplicity, easy accessibility, and mild oxidative conditions suggest that the present strategy might be useful for the assembly of bromochloromethyl functional groups in drug discovery.

Catalyst-Free One-Pot Synthesis of Novel Heteroarylamine Substituted Furo[3,2-c]coumarins

Synlett ◽  
2018 ◽  
Vol 29 (12) ◽  
pp. 1589-1592 ◽  
Author(s):  
Abolfazl Olyaei ◽  
Mahnaz Saraei ◽  
Reyhaneh Khoeiniha
Keyword(s):  
Michael Addition ◽  
Aldol Condensation ◽  
Ring Closure ◽  
Dehydration Reaction ◽  
One Pot ◽  
Catalyst Free ◽  
One Pot Synthesis ◽  
Tandem Process ◽  
First Time

A high-yielding cyclocondensation of 4-hydroxycoumarin, phenylglyoxal monohydrate, and heteroarylamines proceeds without catalysis, which gives novel functionalized furo[3,2-c]coumarins and heteroarylamino alkylation of coumarin products in acetonitrile under reflux, is reported for the first time. This tandem process involves sequentially an aldol condensation, Michael addition, a ring closure, and dehydration reaction.

ChemInform Abstract: The Thiocarbonyl “S” Is Softer than Thiolate “S”: A Catalyst-Free One-Pot Synthesis of Isothiocyanates in Water.

ChemInform ◽  
2010 ◽  
Vol 41 (32) ◽  
pp. no-no
Author(s):  
Latonglila Jamir ◽  
Abdur Rezzak Ali ◽  
Harisadhan Ghosh ◽  
Francis A. S. Chipem ◽  
Bhisma K. Patel
Keyword(s):  
One Pot ◽  
Catalyst Free ◽  
One Pot Synthesis

Isocyanide-based three component reaction for synthesis of highly cyano substituted furan derivatives

RSC Advances ◽  
2016 ◽  
Vol 6 (32) ◽  
pp. 26783-26790 ◽  
Author(s):  
Hamid Reza Safaei ◽  
Farbod Dehbozorgi
Keyword(s):  
Solvent Free ◽  
One Pot ◽  
Furan Derivatives ◽  
Catalyst Free ◽  
One Pot Synthesis ◽  
Three Component Reaction

A rapid and efficient solvent-free one-pot synthesis of novel alkyl amino aryl furan tricarbonitrile derivatives is described under catalyst-free conditions.

Catalyst-free one-pot synthesis of benzimidazoles from 1,2-diaminoarenes and alcohols

2014 ◽  
Vol 55 (48) ◽  
pp. 6520-6525 ◽  
Author(s):  
Mahender Reddy Marri ◽  
Swamy Peraka ◽  
Arun Kumar Macharla ◽  
Naresh Mameda ◽  
Srujana Kodumuri ◽  
...  
Keyword(s):  
One Pot ◽  
Catalyst Free ◽  
One Pot Synthesis

scholarly journals Nano-Rb2HPW12O40 as an Efficient and Novel Catalyst for One-Pot Synthesis of β-Amino Ketones

2016 ◽  
pp. 781-789
Author(s):  
Fatemeh Moradgholi ◽  
Jalil Lari ◽  
Mahnaz Vahidi Parsa ◽  
Mehran Mirkharrazi
Keyword(s):  
One Pot ◽  
One Pot Synthesis ◽  
Novel Catalyst
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