A Novel Synthesis of γ,δ-Unsaturated Aldehydes from α-Formyl-γ-lactones

2011 ◽  
Vol 94 (7) ◽  
pp. 1216-1225 ◽  
Author(s):  
Roger L. Snowden ◽  
Robert Brauchli ◽  
Simon Linder
Synthesis ◽  
2002 ◽  
Vol 1978 (01) ◽  
pp. 67-70 ◽  
Author(s):  
G. ROUSSEAU ◽  
P. LE PERCHEC ◽  
J. CONIA

2000 ◽  
Author(s):  
Thorsten Schroer ◽  
Karl O. Christe
Keyword(s):  

1999 ◽  
Vol 14 (supplement) ◽  
pp. 74-75
Author(s):  
Akira HIRATSUKA ◽  
Kenichiro HIROSE ◽  
Hiroaki NAKANO ◽  
Tadashi WATABE

2017 ◽  
Vol 21 (19) ◽  
Author(s):  
K. O'Reilly ◽  
M. K. Gupta ◽  
H. Gandhi ◽  
V. P. Kumar ◽  
T. P. O'Sullivan

2020 ◽  
Vol 17 (5) ◽  
pp. 396-403
Author(s):  
Nalla Krishna Rao ◽  
Tentu Nageswara Rao ◽  
Botsa Parvatamma ◽  
Y. Prashanthi ◽  
Ravi Kumar Cheedarala

Aims: A series of six 4-benzylidene-2-((1-phenyl-3,4-dihydro isoquinoline-2(1H)-yl)methyloxazol- 5(4H)-one derivatives were synthesized by condensation of substituted aryl aldehydes with 2-(2-(1-phenyl-3,4- dihydro isoquinoline-2(1H)-acetamido)acetic acid in the presence of sodium acetate, acetic anhydride and zinc oxide as catalysts. Background: Novel Synthesis of 4-Benzylidene-2-((1-phenyl-3,4-dihy droisoquinoline-2(1H)-yl)methyl)oxazol- 5(4H)-one derivatives using 1,2,3,Tetrahydroisoquinoline and their antimicrobial activity. Objective: The title compounds can be synthesized from 1,2,3,4-tetrahydroisoquinoline. Methods: The target molecules, i.e., 4-benzylidene-2-((1-phenyl-3, 4-dihydro isoquinoline-2(1H)-yl) methyl) oxazol-5(4H)-one derivatives (8a-8f) have been synthesized from 1,2,3,4-tetrahydroisoquinoline which was prepared from benzoic acid in few steps. Results: All the six compounds were evaluated based on advanced spectral data (1H NMR, 13C NMR & LCMS), and the chemical structures of all compounds were determined by elemental analysis. Conclusion: Antibacterial activity of the derivatives was examined for the synthesized compounds and results indicate that compound with bromine substitution has a good activity profile.


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