Synthesis and Biological Evaluation of Potent Bisubstrate Inhibitors of the Enzyme CatecholO-Methyltransferase (COMT) Lacking a Nitro Group

2006 ◽  
Vol 89 (9) ◽  
pp. 1856-1887 ◽  
Author(s):  
Ralph Paulini ◽  
Christian Lerner ◽  
François Diederich ◽  
Roland Jakob-Roetne ◽  
Gerhard Zürcher ◽  
...  
Keyword(s):  
Nitro Group ◽  
Biological Evaluation ◽  
Bisubstrate Inhibitors ◽  
Synthesis And Biological Evaluation

Synthesis and biological evaluation of lipophilic Ca1a2L analogues as potential bisubstrate inhibitors of protein:geranylgeranyl transferase-1

2005 ◽  
Vol 13 (5) ◽  
pp. 1463-1475 ◽  
Author(s):  
Farid El Oualid ◽  
Jayand Baktawar ◽  
Ingrid M. Leroy ◽  
Hans van den Elst ◽  
Louis H. Cohen ◽  
...  
Keyword(s):  
Biological Evaluation ◽  
Bisubstrate Inhibitors ◽  
Synthesis And Biological Evaluation
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