β-Peptides: Synthesis by Arndt-Eistert homologation with concomitant peptide coupling. Structure determination by NMR and CD spectroscopy and by X-ray crystallography. Helical secondary structure of a β-hexapeptide in solution and its stability towards pe

1996 ◽  
Vol 79 (4) ◽  
pp. 913-941 ◽  
Author(s):  
Dieter Seebach ◽  
Mark Overhand ◽  
Florian N. M. Kühnle ◽  
Bruno Martinoni ◽  
Lukas Oberer ◽  
...  
Keyword(s):  
Secondary Structure ◽  
Structure Determination ◽  
Cd Spectroscopy ◽  
Peptide Coupling ◽  
X Ray ◽  
X Ray Crystallography ◽  
Coupling Structure ◽  
Peptides Synthesis

Poly-N-methylated α-peptides: synthesis and X-ray structure determination of β-strand forming foldamers

2006 ◽  
pp. 497-499 ◽  
Author(s):  
Suode Zhang ◽  
Samran Prabpai ◽  
Palangpon Kongsaeree ◽  
Per I. Arvidsson
Keyword(s):  
Structure Determination ◽  
X Ray ◽  
Peptides Synthesis

scholarly journals Howard Flack and the Flack Parameter

Chemistry ◽  
2020 ◽  
Vol 2 (4) ◽  
pp. 796-804
Author(s):  
David John Watkin ◽  
Richard Ian Cooper
Keyword(s):  
Structure Determination ◽  
Standard Uncertainty ◽  
Crystallographic Structure ◽  
X Ray ◽  
Original Algorithm ◽  
X Ray Crystallography ◽  
Chiral Materials

The Flack Parameter is now almost universally reported for all chiral materials characterized by X-ray crystallography. Its elegant simplicity was an inspired development by Howard Flack, and although the original algorithm for its computation has been strengthened by other workers, it remains an essential outcome for any crystallographic structure determination. As with any one-parameter metric, it needs to be interpreted in the context of its standard uncertainty.

scholarly journals 2-(3,5-Dimethyl-1H-pyrazol-1-yl)thiazolo[4,5-b]pyridine

Molbank ◽  
10.3390/m1077 ◽  
2019 ◽  
Vol 2019 (3) ◽  
pp. M1077
Author(s):  
Lan ◽  
Zheng ◽  
Wang
Keyword(s):  
Nmr Spectroscopy ◽  
Single Crystal ◽  
1H Nmr ◽  
Structure Determination ◽  
1H Nmr Spectroscopy ◽  
Pyrazole Ring ◽  
Hydrogen Atoms ◽  
X Ray ◽  
X Ray Crystallography

The compound 2-(3,5-dimethyl-1H-pyrazol-1-yl)thiazolo[4,5-b]pyridine (1) was synthesized with a yield of 71% by the reaction of 1-(thiazolo[4,5-b]pyridine-2-yl)hydrazine and acetylacetone. The structure was characterized by a single-crystal X-ray structure determination as well as 1H and 13C{1H} NMR spectroscopy. X-ray crystallography on 1 confirms the molecule consists of a pyridine–thiazole moiety and the pyrazole ring, and all non-hydrogen atoms are planar.

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