Learning-dependent plasticity of hippocampal CA1 pyramidal neuron postburst afterhyperpolarizations and increased excitability after inhibitory avoidance learning depend upon basolateral amygdala inputs

Hippocampus ◽  
2012 ◽  
Vol 22 (8) ◽  
pp. 1703-1719 ◽  
Author(s):  
George E. Farmer ◽  
Lucien T. Thompson
Keyword(s):  
Pyramidal Neuron ◽  
Avoidance Learning ◽  
Basolateral Amygdala ◽  
Inhibitory Avoidance ◽  
Dependent Plasticity ◽  
Hippocampal Ca1 ◽  
Inhibitory Avoidance Learning ◽  
Ca1 Pyramidal Neuron

NMDA receptor antagonism in the basolateral amygdala blocks enhancement of inhibitory avoidance learning in previously trained rats

2000 ◽  
Vol 112 (1-2) ◽  
pp. 99-105 ◽  
Author(s):  
Rafael Roesler ◽  
Mônica R.M Vianna ◽  
Fernanda de-Paris ◽  
Cléverson Rodrigues ◽  
Márcia K Sant’Anna ◽  
...  
Keyword(s):  
Nmda Receptor ◽  
Avoidance Learning ◽  
Basolateral Amygdala ◽  
Inhibitory Avoidance ◽  
Receptor Antagonism ◽  
Inhibitory Avoidance Learning

Lesions of the Basolateral Amygdala Complex Block Propofol-induced Amnesia for Inhibitory Avoidance Learning in Rats

2001 ◽  
Vol 95 (3) ◽  
pp. 708-715 ◽  
Author(s):  
Michael T. Alkire ◽  
Almira Vazdarjanova ◽  
Heather Dickinson-Anson ◽  
Nathan S. White ◽  
Larry Cahill
Keyword(s):  
Avoidance Learning ◽  
Basolateral Amygdala ◽  
Inhibitory Avoidance ◽  
Treated Group ◽  
Dark Side ◽  
Memory Latency ◽  
Treated Animal ◽  
Unitary Theory ◽  
Brain Site ◽  
Inhibitory Avoidance Learning

Background As the unitary theory of anesthesia gives way to the "multiple sites, multiple mechanisms" concept, the sites involved in mediating the components of anesthesia must be identified. In the current study, we test the hypothesis that the basolateral amygdala complex (BLAC) is a brain site involved with mediating propofol-induced amnesia. Methods Male Sprague-Dawley rats were divided into two groups, sham-operated control animals and rats given bilateral excitotoxic N-methyl-D-aspartate lesions of the BLAC. For each group, animals were given intraperitoneal saline or propofol (25 mg/kg) 5 min before inhibitory avoidance learning. Rats were given a foot shock (0.4 mA) upon entering the dark side of a two-sided apparatus. Rats could escape additional shock by returning to and staying in the light side. Training ended after shock avoidance for greater than 60 s. Memory was tested at 24 h. Longer latencies to enter the dark side 24 h after training imply better memory. Results Sham-saline-treated animals had a robust memory latency (median latency [interquartile range] = 300 [163-567] s). Sham-propofo-treated animals exhibited a significant anterograde amnesia (latency = 63 [14-111] s) (P < 0.05 vs. sham-saline-treated animal). Both the saline-injected and propofol-injected animals with BLAC lesions showed robust memory (latency = 300 [264-485] and 323 [143480] s, respectively). These latencies did not differ from performance in the sham-saline-treated group and were significantly higher than the latency of the sham-propofol-treated group (both P < 0.05). Conclusions Discrete BLAC lesions blocked the amnestic effect of propofol. BLAC activity appears to be a requirement for propofol-induced amnesia. This finding suggests that the BLAC is a key brain site mediating anesthetic-induced amnesia.

Neonatal 6-hydroxydopa, but not DSP-4, elevates brainstem monoamines and impairs inhibitory avoidance learning in developing rats

1989 ◽  
Vol 493 (2) ◽  
pp. 258-268 ◽  
Author(s):  
Catherine A. Cornwell-Jones ◽  
Michael W. Decker ◽  
Julia W. Chang ◽  
Barry Cole ◽  
Kimberly M. Goltz ◽  
...  
Keyword(s):  
Avoidance Learning ◽  
Inhibitory Avoidance ◽  
Inhibitory Avoidance Learning

Dynamics of dendritic spines in dorsal striatum after retrieval of moderate and strong inhibitory avoidance learning

Neuroscience ◽  
2021 ◽  
Author(s):  
Paola C. Bello-Medina ◽  
Andrea C. Medina ◽  
Gina L. Quirarte ◽  
Martha Martínez-Degollado ◽  
Clyo X. Ruiz-López ◽  
...  
Keyword(s):  
Dendritic Spines ◽  
Avoidance Learning ◽  
Dorsal Striatum ◽  
Inhibitory Avoidance ◽  
Inhibitory Avoidance Learning

White Environment Can Be Used as an Aversive Stimulus in Zebrafish Inhibitory Avoidance Learning

Zebrafish ◽  
2019 ◽  
Vol 16 (5) ◽  
pp. 443-450 ◽  
Author(s):  
Bruno Rodrigues dos Santos ◽  
Raissa Cruz dos Santos ◽  
Claudio Alberto Gellis de Mattos Dias ◽  
Caio Maximino ◽  
Amauri Gouveia
Keyword(s):  
Avoidance Learning ◽  
Aversive Stimulus ◽  
Inhibitory Avoidance ◽  
Inhibitory Avoidance Learning

Estimated distribution of specific membrane resistance in hippocampal CA1 pyramidal neuron

2006 ◽  
Vol 1125 (1) ◽  
pp. 199-208 ◽  
Author(s):  
Toshiaki Omori ◽  
Toru Aonishi ◽  
Hiroyoshi Miyakawa ◽  
Masashi Inoue ◽  
Masato Okada
Keyword(s):  
Pyramidal Neuron ◽  
Membrane Resistance ◽  
Hippocampal Ca1 ◽  
Ca1 Pyramidal Neuron ◽  
Specific Membrane
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