scholarly journals Role of estrogen receptor alpha and beta expression and signaling on cognitive function during aging

Hippocampus ◽  
2011 ◽  
Vol 22 (4) ◽  
pp. 656-669 ◽  
Author(s):  
Thomas C. Foster
Keyword(s):  
Estrogen Receptor ◽  
Cognitive Function ◽  
Estrogen Receptor Alpha ◽  
Receptor Alpha

scholarly journals 0329 : Role of the estrogen receptor alpha (ERalpha) in the vascular response to shear stress in mice

2015 ◽  
Vol 7 (2) ◽  
pp. 142
Author(s):  
Julie Favre ◽  
Emilie Vessière ◽  
Anne-Laure Guihot ◽  
Linda Grimaud ◽  
Jean-François Arnal ◽  
...  
Keyword(s):  
Shear Stress ◽  
Estrogen Receptor ◽  
Estrogen Receptor Alpha ◽  
Vascular Response ◽  
Receptor Alpha

scholarly journals The Role of Calcium in the Activation of Estrogen Receptor-Alpha

2011 ◽  
Vol 71 (5) ◽  
pp. 1658-1668 ◽  
Author(s):  
Shailaja D. Divekar ◽  
Geoffrey B. Storchan ◽  
Katherine Sperle ◽  
David J. Veselik ◽  
Earl Johnson ◽  
...  
Keyword(s):  
Estrogen Receptor ◽  
Estrogen Receptor Alpha ◽  
Receptor Alpha

Role of estrogen receptor alpha on vaginal epithelialization of patients with Mayer–Rokitansky–Kuster–Hauser syndrome submitted to neovaginoplasty using oxidized regenerated cellulose

2012 ◽  
Vol 23 (4) ◽  
pp. 467-472 ◽  
Author(s):  
Marcio Masashi Kajikawa ◽  
Zsuzsanna Ilona Katalin Jármy-Di Bella ◽  
Gustavo Rubino de Azevedo Focchi ◽  
Juliane Dornelas ◽  
Manoel João Batista Castello Girão ◽  
...  
Keyword(s):  
Estrogen Receptor ◽  
Estrogen Receptor Alpha ◽  
Regenerated Cellulose ◽  
Oxidized Regenerated Cellulose ◽  
Receptor Alpha

scholarly journals The role of total and cartilage-specific estrogen receptor alpha expression for the ameliorating effect of estrogen treatment on arthritis

2014 ◽  
Vol 16 (4) ◽  
pp. R150 ◽  
Author(s):  
Cecilia Engdahl ◽  
Anna E Börjesson ◽  
Huamei F Forsman ◽  
Annica Andersson ◽  
Alexandra Stubelius ◽  
...  
Keyword(s):  
Estrogen Receptor ◽  
Estrogen Receptor Alpha ◽  
Estrogen Treatment ◽  
Receptor Alpha ◽  
And Cartilage

scholarly journals Role of TRAP1 and estrogen receptor alpha in patients with ovarian cancer -A study of the OVCAD consortium

2012 ◽  
Vol 11 (1) ◽  
pp. 69 ◽  
Author(s):  
Stefanie Aust ◽  
Anna Bachmayr-Heyda ◽  
Petra Pateisky ◽  
Dan Tong ◽  
Silvia Darb-Esfahani ◽  
...  
Keyword(s):  
Ovarian Cancer ◽  
Estrogen Receptor ◽  
Estrogen Receptor Alpha ◽  
Receptor Alpha

scholarly journals Membrane estrogen receptor alpha (ERα) participates in flow-mediated dilation in a ligand-independent manner

eLife ◽  
2021 ◽  
Vol 10 ◽  
Author(s):  
Julie Favre ◽  
Emilie Vessieres ◽  
Anne-Laure Guihot ◽  
Coralyne Proux ◽  
Linda Grimaud ◽  
...  
Keyword(s):  
Estrogen Receptor ◽  
Estrogen Receptor Alpha ◽  
Ex Vivo ◽  
Flow Mediated Dilation ◽  
Wild Type ◽  
Resistance Arteries ◽  
Independent Manner ◽  
Receptor Alpha ◽  
No Bioavailability

Estrogen receptor alpha (ERα) activation by estrogens prevents atheroma through its nuclear action whereas plasma membrane-located ERα accelerates endothelial healing. The genetic deficiency of ERα was associated with a reduction in flow-mediated dilation (FMD) in one man. Here, we evaluated ex vivo the role of ERα on FMD of resistance arteries. FMD, but not agonist (acetylcholine, insulin)-mediated dilation, was reduced in male and female mice lacking ERα (Esr1-/- mice) compared to wild-type mice and was not dependent on the presence of estrogens. In C451A-ERα mice lacking membrane ERα, not in mice lacking AF2-dependent nuclear ERα actions, FMD was reduced, and restored by antioxidant treatments. Compared to wild-type mice, isolated perfused kidneys of C451A-ERα mice revealed a decreased flow-mediated nitrate production and an increased H2O2 production. Thus, endothelial membrane ERα promotes NO bioavailability through inhibition of oxidative stress and thereby participates in FMD in a ligand-independent manner.

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