scholarly journals Multiple repetitions reveal functionally and anatomically distinct patterns of hippocampal activity during continuous recognition memory

Hippocampus ◽  
2008 ◽  
Vol 18 (10) ◽  
pp. 975-980 ◽  
Author(s):  
Jeffrey D. Johnson ◽  
L. Tugan Muftuler ◽  
Michael D. Rugg
Keyword(s):  
Recognition Memory ◽  
Hippocampal Activity

scholarly journals In Search of Recollection and Familiarity Signals in the Hippocampus

2010 ◽  
Vol 22 (1) ◽  
pp. 109-123 ◽  
Author(s):  
Peter E. Wais ◽  
Larry R. Squire ◽  
John T. Wixted
Keyword(s):  
Prefrontal Cortex ◽  
Recognition Memory ◽  
Source Memory ◽  
Medial Temporal Lobe ◽  
Parahippocampal Gyrus ◽  
Memory Strength ◽  
Similar Extent ◽  
High Confidence ◽  
Hippocampal Activity ◽  
Memory Experiment

fMRI studies of recognition memory have often been interpreted to mean that the hippocampus selectively subserves recollection and that adjacent regions selectively subserve familiarity. Yet, many of these studies have confounded recollection and familiarity with strong and weak memories. In a source memory experiment, we compared correct source judgments (which reflect recollection) and incorrect source judgments (often thought to reflect familiarity) while equating for old–new memory strength by including only high-confidence hits in the analysis. Hippocampal activity associated with both correct source judgments and incorrect source judgments exceeded the activity associated with forgotten items and did so to a similar extent. Further, hippocampal activity was greater for high-confidence old decisions relative to forgotten items even when source decisions were at chance. These results identify a recollection signal in the hippocampus and may identify a familiarity signal as well. Similar results were obtained in the parahippocampal gyrus. Unlike in the medial temporal lobe, activation in prefrontal cortex increased differentially in association with source recollection.

scholarly journals Hippocampal activity during recognition memory co-varies with the accuracy and confidence of source memory judgments

Hippocampus ◽  
2011 ◽  
Vol 22 (6) ◽  
pp. 1429-1437 ◽  
Author(s):  
Sarah S. Yu ◽  
Jeffrey D. Johnson ◽  
Michael D. Rugg
Keyword(s):  
Recognition Memory ◽  
Source Memory ◽  
Hippocampal Activity

scholarly journals Specific hippocampal interneurons shape consolidation of recognition memory

2019 ◽  
Author(s):  
Jose F. Oliveira da Cruz ◽  
Arnau Busquets-Garcia ◽  
Zhe Zhao ◽  
Marjorie Varilh ◽  
Gianluca Lavanco ◽  
...  
Keyword(s):  
Recognition Memory ◽  
Cannabinoid Receptor ◽  
Long Term Potentiation ◽  
Cognitive Outcomes ◽  
Dependent Manner ◽  
Term Potentiation ◽  
Hippocampal Activity ◽  
Object Recognition Memory

SUMMARYA complex array of different inhibitory interneurons tightly controls hippocampal activity, but how such diversity specifically impacts on memory processes is scantly known. We found that a small subclass of type-1 cannabinoid receptor (CB1)-expressing hippocampal interneurons determines episodic-like memory consolidation by linking dopamine D1 receptor signaling to GABAergic transmission.Mice lacking CB1 in D1-positive cells (D1-CB1-KO) displayed impaired long-term, but not short-term, object recognition memory. Re-expression of CB1 in hippocampal, but not striatal, D1-positive cells rescued this memory impairment. Learning induced a facilitation of in vivo hippocampal long-term potentiation (LTP), which was abolished in mutant mice. Chemogenetic and pharmacological experiments revealed that both CB1-mediated memory and associated LTP facilitation involves the local control of GABAergic inhibition in a D1-dependent manner.This study reveals that CB1-/D1-expressing interneurons shape hippocampal circuits to sustain recognition memory, thereby identifying a mechanism linking the diversity of hippocampal interneurons to specific behavioral and cognitive outcomes.

Catechol-O-methyltransferase Val158Met association with parahippocampal physiology during memory encoding in schizophrenia

2010 ◽  
Vol 41 (8) ◽  
pp. 1721-1731 ◽  
Author(s):  
A. Di Giorgio ◽  
G. Caforio ◽  
G. Blasi ◽  
P. Taurisano ◽  
L. Fazio ◽  
...  
Keyword(s):  
Recognition Memory ◽  
Healthy Subjects ◽  
Memory Task ◽  
Blood Oxygen Level Dependent ◽  
Dose Effect ◽  
Memory Encoding ◽  
Blood Oxygen Level ◽  
Hippocampal Activity ◽  
Increase Risk ◽  
Dopamine Signaling

BackgroundCatechol-O-methyltransferase (COMT) Val158Met has been associated with activity of the mesial temporal lobe during episodic memory and it may weakly increase risk for schizophrenia. However, how this variant affects parahippocampal and hippocampal physiology when dopamine transmission is perturbed is unclear. The aim of the present study was to compare the effects of the COMT Val158Met genotype on parahippocampal and hippocampal physiology during encoding of recognition memory in patients with schizophrenia and in healthy subjects.MethodUsing blood oxygen level-dependent (BOLD) functional magnetic resonance imaging (fMRI), we studied 28 patients with schizophrenia and 33 healthy subjects matched for a series of sociodemographic and genetic variables while they performed a recognition memory task.ResultsWe found that healthy subjects had greater parahippocampal and hippocampal activity during memory encoding compared to patients with schizophrenia. We also found different activity of the parahippocampal region between healthy subjects and patients with schizophrenia as a function of the COMT genotype, in that the predicted COMT Met allele dose effect had an opposite direction in controls and patients.ConclusionsOur results demonstrate a COMT Val158Met genotype by diagnosis interaction in parahippocampal activity during memory encoding and may suggest that modulation of dopamine signaling interacts with other disease-related processes in determining the phenotype of parahippocampal physiology in schizophrenia.

scholarly journals The human hippocampus contributes to both the recollection and familiarity components of recognition memory

2015 ◽  
Vol 112 (46) ◽  
pp. 14378-14383 ◽  
Author(s):  
Maxwell B. Merkow ◽  
John F. Burke ◽  
Michael J. Kahana
Keyword(s):  
Recognition Memory ◽  
Medial Temporal Lobe ◽  
Memory Performance ◽  
Process Models ◽  
Dual Process ◽  
Hippocampal Activity ◽  
High Frequency Activity ◽  
Electrophysiological Signal ◽  
Temporal Lobe Lesions

Despite a substantial body of work comprising theoretical modeling, the effects of medial temporal lobe lesions, and electrophysiological signal analysis, the role of the hippocampus in recognition memory remains controversial. In particular, it is not known whether the hippocampus exclusively supports recollection or both recollection and familiarity—the two latent cognitive processes theorized to underlie recognition memory. We studied recognition memory in a large group of patients undergoing intracranial electroencephalographic (iEEG) monitoring for epilepsy. By measuring high-frequency activity (HFA)—a signal associated with precise spatiotemporal properties—we show that hippocampal activity during recognition predicted recognition memory performance and tracked both recollection and familiarity. Through the lens of dual-process models, these results indicate that the hippocampus supports both the recollection and familiarity processes.

How do memory modules differentially contribute to familiarity and recollection?

2019 ◽  
Vol 42 ◽  
Author(s):  
Olya Hakobyan ◽  
Sen Cheng
Keyword(s):  
Recognition Memory ◽  
Experimental Evidence ◽  
Subjective Experience ◽  
Target Article ◽  
Memory Modules ◽  
Familiarity And Recollection ◽  
Memory Contents

Abstract We fully support dissociating the subjective experience from the memory contents in recognition memory, as Bastin et al. posit in the target article. However, having two generic memory modules with qualitatively different functions is not mandatory and is in fact inconsistent with experimental evidence. We propose that quantitative differences in the properties of the memory modules can account for the apparent dissociation of recollection and familiarity along anatomical lines.

Learning From (Test) Experience

2020 ◽  
Vol 228 (4) ◽  
pp. 264-277 ◽  
Author(s):  
Evan E. Mitton ◽  
Chris M. Fiacconi
Keyword(s):  
Recognition Memory ◽  
Test Performance ◽  
Memory Performance ◽  
Judgments Of Learning ◽  
Visual Images ◽  
Memory Tests ◽  
Recognition Memory Performance ◽  
Study Test ◽  
Explicit Feedback

Abstract. To date there has been relatively little research within the domain of metamemory that examines how individuals monitor their performance during memory tests, and whether the outcome of such monitoring informs subsequent memory predictions for novel items. In the current study, we sought to determine whether spontaneous monitoring of test performance can in fact help individuals better appreciate their memory abilities, and in turn shape future judgments of learning (JOLs). Specifically, in two experiments we examined recognition memory for visual images across three study-test cycles, each of which contained novel images. We found that across cycles, participants’ JOLs did in fact increase, reflecting metacognitive sensitivity to near-perfect levels of recognition memory performance. This finding suggests that individuals can and do monitor their test performance in the absence of explicit feedback, and further underscores the important role that test experience can play in shaping metacognitive evaluations of learning and remembering.

Perceptual Effects and Recollective Experience in Face Recognition

2005 ◽  
Vol 52 (3) ◽  
pp. 224-231 ◽  
Author(s):  
Chrisanthi Nega
Keyword(s):  
Face Recognition ◽  
Recognition Memory ◽  
Congruency Effect ◽  
Facial Recognition ◽  
Memory Systems ◽  
Study Time ◽  
Perceptual Fluency ◽  
Recollective Experience ◽  
Trace Strength ◽  
Size Congruency

Abstract. Four experiments were conducted investigating the effect of size congruency on facial recognition memory, measured by remember, know and guess responses. Different study times were employed, that is extremely short (300 and 700 ms), short (1,000 ms), and long times (5,000 ms). With the short study time (1,000 ms) size congruency occurred in knowing. With the long study time the effect of size congruency occurred in remembering. These results support the distinctiveness/fluency account of remembering and knowing as well as the memory systems account, since the size congruency effect that occurred in knowing under conditions that facilitated perceptual fluency also occurred independently in remembering under conditions that facilitated elaborative encoding. They do not support the idea that remember and know responses reflect differences in trace strength.

Application of Information Introduced to Dynamic Message Processing and Enjoyment

2018 ◽  
Vol 30 (4) ◽  
pp. 196-206 ◽  
Author(s):  
Byungho Park ◽  
Rachel L. Bailey
Keyword(s):  
Resource Allocation ◽  
Recognition Memory ◽  
Emotional Processing ◽  
Orienting Response ◽  
Structural Features ◽  
Cognitive Resources ◽  
Coding System ◽  
Message Complexity ◽  
Cognitive Resource ◽  
Cognitive Overload

Abstract. In an effort to quantify message complexity in such a way that predictions regarding the moment-to-moment cognitive and emotional processing of viewers would be made, Lang and her colleagues devised the coding system information introduced (or ii). This coding system quantifies the number of structural features that are known to consume cognitive resources and considers it in combination with the number of camera changes (cc) in the video, which supply additional cognitive resources owing to their elicitation of an orienting response. This study further validates ii using psychophysiological responses that index cognitive resource allocation and recognition memory. We also pose two novel hypotheses regarding the confluence of controlled and automatic processing and the effect of cognitive overload on enjoyment of messages. Thirty television advertisements were selected from a pool of 172 (all 20 s in length) based on their ii/cc ratio and ratings for their arousing content. Heart rate change over time showed significant deceleration (indicative of increased cognitive resource allocation) for messages with greater ii/cc ratios. Further, recognition memory worsened as ii/cc increased. It was also found that message complexity increases both automatic and controlled allocations to processing, and that the most complex messages may have created a state of cognitive overload, which was received as enjoyable by the participants in this television context.

Sign in / Sign up

Export Citation Format

Share Document