Hepatocytes Induce Change in Their Neighbors by YAP‐ing at Them

Hepatology ◽  
2021 ◽  
Author(s):  
EeeLN Buckarma ◽  
Rory Smoot
Keyword(s):  
Author(s):  
Sumartini ◽  
Sellen Gurusmatika ◽  
Wan Amira

Seaweed is considered high class marine and fisheries sector in international demand for its derivative products. One of traditional use of seaweed as food is stick snack which is widely consumed due to its crunchiness and deliciousness. The objective of this study was to characterize the proximate analysis, hardness, and sensory perception of stick snack derived from seaweed. Seaweed stick were prepared with varying food additives such as  sodium acid phyorposphate (SAPP), steaoryl lactylate (SSL), sodium bicarbonate (NaHCO3), and control (without addition of food additives). The results confirmed that the use of food additives induce change in proximate, hardness, and sensory perception. Seaweed stick with addition NaHCO3 has the highest fat content while seaweed stick with addition of SAPP has  the highest crispness. In addition, sensory test showed that seaweed stick with addition with NaHCO3 provide the highest acceptance in texture and flavour.


2007 ◽  
Vol 10 (20) ◽  
pp. 3662-3667 ◽  
Author(s):  
Latifeh Pourakbar . ◽  
Masoud Khayami . ◽  
Jalil Khara . ◽  
Tayabeh Farbodnia .

Author(s):  
Kyrill Meyer

How natural resources are used in modern society is considered a high-priority topic within national and international political and social debate. Increases in energy efficiency, the use of renewable energy sources and emission control are important aspects of this subject that must be considered. A deeper understanding of existing infrastructure and the willingness to change on an individual and social level are needed, while determining factors like demographic change are taken into account. This paper introduces the energy-efficient city of tomorrow as a city of socio-technical networks that interact and are a basis for energy-related optimizations. Furthermore, the authors discuss the special role that IT-enabled services can play in understanding and changing those networks. To illustrate, the authors present a service as a case study that illustrates how services can provides relevant information and help to induce change.


Author(s):  
Seokhwan Kim ◽  
Yongho Choi ◽  
Junho Seo ◽  
No-Cheol Park ◽  
Young-Pil Park ◽  
...  

The change of attitude of the spindle system can induce change in its resonance frequencies. The attitude of the spindle system is determined by each rotating event. The change in resonance frequency affects stiffness and damping ratio of the spindle system. Therefore, the dynamic behavior of a spindle system is affected by the change of dynamic coefficients of the spindle system under non-operational vibration.


1994 ◽  
Vol 51 (1) ◽  
pp. 226-246 ◽  
Author(s):  
Lionel Johnson

The dominant fish populations in undisturbed arctic lakes are characterized as being in a state of "least specific dissipation": the greatest biomass attainable for a given energy input. A survey of autonomous ecosystems in various parts of the world indicated that this pattern is widespread. It is concluded that ecosystems are formed at the point of intersection of two established physical principles: the "principle of most action" (≈least dissipation or conservation of free energy) and the "principle of least action". "Action" is defined as the product of energy times time (joule-seconds). The trend to "most action" necessitates deceleration of energy flow: "least action" accelerates energy flow. For an ecosystem to survive over ecological time, the principle of most action must override the principle of least action. In that different species of organism have different capacities to conserve free energy (increase action), a hierarchy is formed locally in which action increases at each hierarchical level. Over the long term, as a result of genetic instability, both principles induce change, but the principle of least action dominates system behaviour causing increasingly rapid energy dissipation. Evolution is the resultant of these two countervailing forces.


Author(s):  
Nima Tamaddoni ◽  
Graham J. Taylor ◽  
Stephen A. Sarles

In this work, a recently developed method for forming copolymer-stabilized interfaces (CSI) between aqueous droplets is pursued to as a means to construct smart materials and systems. The ABA type copolymer employed consists of two hydrophilic (PEO) groups sandwiching a hydrophobic PDMS core. Aqueous droplets submerged in triblock copolymer (PEO-PDMS-PEO)-oil mixtures are rapidly coated in copolymer monolayers, however, unlike phospholipid-stabilized droplet interface bilayers (DIBs), electrical measurements reveal that there is no spontaneous formation of a “thinned” interface with droplet contact alone. The capacitance of the interface begins increasing significantly only upon application of sufficient voltage (>100mV), and capacitance then stabilizes within minutes. Further, the interfacial capacitance and area decreases when applied voltage is reduced back to 0mV, and droplets eventually return to their initial separated state. The fact that droplet adhesion and formation of the interface is voltage dependent and completely reversible clearly distinguishes a CSI from a DIB, and the novel polymer based interface is significantly more robust with average rupture potential of ≥ 800mV compared to 200–300mV with DIBs. Durable and stable CSIs could feasibly be used in applications ranging from sensing and energy harvesting to mechanical actuation. To demonstrate, this work introduces a new version of the DIB based hair cell sensor, now replacing lipids with block copolymers to provide greater durability, stability, and resistance to rupture when subjected to airflow. We calculate the current generated by the vibrating membranes in DIBs and CSIs to study the influence of surfactant selection on the hair cell durability and the related airflow operation range. We conclude that the hair cell constructed using triblock copolymer, as opposed to a DIB, withstands higher nominal airflow speeds (45m/s) and higher applied bias voltages (i.e. 0.1–1V) without rupturing. The ability to apply higher voltages provides a means of tuning the hair-cell sensitivity. Separately, the results of initial trials demonstrate the possibility for voltage-controlled shape change using networks of droplets and CSIs. The ability to apply large voltages and induce change in interfacial area leads to rearrangement of the droplet networks due to conservation of volume. Several embodiments of possible actuators based on this mechanism are discussed. In concert, the various aspects of this work highlight the potential use of CSIs in developing novel, reliable smart materials for sensing and actuation.


2014 ◽  
Vol 7 (4) ◽  
pp. 337-353 ◽  
Author(s):  
Ramesh Dangol ◽  
Anthony Kos

Purpose – The purpose of this paper is to propose a new way to distinguish a firm’s dynamic capabilities from operational capabilities. Design/methodology/approach – Conceptual paper/literature review. Findings – Current literature on dynamic capabilities posits that dynamic capabilities are those firm capabilities that can induce change in other capabilities, while operational capabilities are static. Distinguishing between these capabilities in this manner is not helpful because changes occur continuously in all capabilities to at least some extent. In addition, empirical studies show that even task-level operational capabilities can change on their own and can induce change in other capabilities. In contrast to focussing on the presence or lack of change to determine if a capability is dynamic or operational, this paper distinguishes between them by determining a priori the expected nature of the outcome. By focussing on the outcomes of change rather than the changes themselves, this paper proposes that capabilities should be considered operational if they produce outcomes that can be predicted using probability distribution while those capabilities that produce outcomes that cannot be predicted using probability distribution should be considered dynamic. Research limitations/implications – Future research on dynamic capabilities should not only investigate whether or not change is occurring, but the outcome of change to understand whether a change is precipitated by dynamic or operational capabilities. Originality/value – Existing dynamic capabilities literature is unclear about how to distinguish between dynamic capabilities from operational capabilities. Previous research attempts to distinguish these capabilities by arguing dynamic capabilities are those firm capabilities that can induce change in other capabilities, while operational capabilities are static and do not induce change. This is not particularly helpful. A clear distinction between dynamic and operational capabilities could facilitate further advancement of the dynamic capability literature; this study makes a rudimentary effort to distinguish between them.


2003 ◽  
Vol 10 (2) ◽  
pp. 233-255 ◽  
Author(s):  
Massimo Turatto ◽  
Sandro Bettella ◽  
Carlo Umiltà ◽  
Bruce Bridgeman

2019 ◽  
Vol 30 (3) ◽  
pp. 436-443 ◽  
Author(s):  
Richard Yao ◽  
Katherine Wood ◽  
Daniel J. Simons

Magicians claim that an abrupt change in the direction of movement can attract attention, allowing them to hide their method for a trick in plain sight. In three experiments involving 43 total subjects, we tested this claim by examining whether a sudden directional change can induce change blindness. Subjects were asked to detect an instantaneous orientation change of a single item in an array of Gabor patches; this change occurred as the entire array moved across the display. Subjects consistently spotted the change if it occurred while the array moved along a straight path but missed it when it occurred as the array changed direction. This method of inducing change blindness leaves the object in full view during the change; requires no additional distractions, visual occlusion, or global transients; and worked in every subject tested here. This phenomenon joins a body of magic-inspired work that yields insights into perception and attention.


2003 ◽  
Vol 20 (3) ◽  
pp. 243-253 ◽  
Author(s):  
Anders Malmsjö ◽  
Erika Övelius

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