Deficiency in Embryonic Stem Cell Marker Reduced Expression 1 Activates Mitogen‐Activated Protein Kinase Kinase 6–Dependent p38 Mitogen‐Activated Protein Kinase Signaling to Drive Hepatocarcinogenesis

Hepatology ◽  
2020 ◽  
Vol 72 (1) ◽  
pp. 183-197 ◽  
Author(s):  
Steve T. Luk ◽  
Kai‐Yu Ng ◽  
Lei Zhou ◽  
Man Tong ◽  
Tin‐Lok Wong ◽  
...  
Keyword(s):  
Stem Cell ◽  
Protein Kinase ◽  
Embryonic Stem Cell ◽  
Embryonic Stem ◽  
Mitogen Activated Protein Kinase ◽  
Stem Cell Marker ◽  
Cell Marker ◽  
Mitogen Activated Protein ◽  
Protein Kinase Signaling ◽  
Protein Kinase Kinase

scholarly journals Increased Stem Cell Marker Expressions during the Peri-Implantation Period in the Rat Endometrium: Constructive Role of Exogenous Zinc and/or Progesterone

2014 ◽  
Vol 2014 ◽  
pp. 1-10 ◽  
Author(s):  
Cagdas Sahin ◽  
Ozlem Yilmaz Dilsiz ◽  
Sirin Bakti Demiray ◽  
Ozgur Yeniel ◽  
Mete Ergenoglu ◽  
...  
Keyword(s):  
Stem Cell ◽  
Embryonic Stem Cell ◽  
Embryonic Stem ◽  
Stem Cell Marker ◽  
Control Group ◽  
Stem Cell Markers ◽  
Cell Marker ◽  
Cell Markers ◽  
Embryonic Stem Cell Markers ◽  
Implantation Period

Background. The aim of this study is to determine the effects of zinc and/or progesterone via the expression ofαvβ5 integrins and Vitronectins and embryonic stem cell markers during the peri-implantation period.Methods. Four experimental groups were organized. All subjects were mated with males of the same strain to induce pregnancy; after 5 days, zinc and/or progesterone were administered. Blood levels of zinc and progesterone were determined on the sixth day and endometrial tissues were obtained in order to evaluate the immunohistochemical expression of integrins and embryonic stem cell markers.Results. Theαvβ5 integrin and vitronectin expression increased in the zinc group compared with the control group and no difference in the progesterone group and zinc + progesterone group. Expression of Klf-4, Sox-2, and c-Myc was found to be increased in the zinc group compared to controls, while no difference was determined between the progesterone, zinc + progesterone, and control groups. Distinctively, expression of the embryonic stem cell marker Oct-4 was increased in all of the experimental groups.Conclusions. Expression ofαvβ5 integrin, vitronectin, and embryonic stem cell markers might be increased by the administration of zinc. Our results suggest that zinc could be useful in the induction of implantation rates.

Expression of embryonic stem cell marker OCT4 in human thyroid neoplasia

2007 ◽  
Vol 115 (S 1) ◽  
Author(s):  
Z Chen ◽  
M Erhuma ◽  
K Rabara ◽  
B Trojanowicz ◽  
J Bialek ◽  
...  
Keyword(s):  
Stem Cell ◽  
Embryonic Stem Cell ◽  
Embryonic Stem ◽  
Stem Cell Marker ◽  
Human Thyroid ◽  
Cell Marker ◽  
Thyroid Neoplasia

scholarly journals Age-Dependent Association between Protein Expression of the Embryonic Stem Cell Marker Cripto-1 and Survival of Glioblastoma Patients

2013 ◽  
Vol 6 (6) ◽  
pp. 732-IN33 ◽  
Author(s):  
Berit B. Tysnes ◽  
Hege A. Sætran ◽  
Sverre J. Mørk ◽  
Naira V. Margaryan ◽  
Geir E. Eide ◽  
...  
Keyword(s):  
Stem Cell ◽  
Protein Expression ◽  
Embryonic Stem Cell ◽  
Embryonic Stem ◽  
Stem Cell Marker ◽  
Cell Marker ◽  
Age Dependent

Atypical expression and distribution of embryonic stem cell marker, OCT4, in human lung adenocarcinoma

2010 ◽  
Vol 102 (6) ◽  
pp. 689-698 ◽  
Author(s):  
Golnaz Karoubi ◽  
Lourdes Cortes-Dericks ◽  
Mathias Gugger ◽  
Domenico Galetta ◽  
Lorenzo Spaggiari ◽  
...  
Keyword(s):  
Stem Cell ◽  
Lung Adenocarcinoma ◽  
Embryonic Stem Cell ◽  
Human Lung ◽  
Embryonic Stem ◽  
Stem Cell Marker ◽  
Cell Marker ◽  
Human Lung Adenocarcinoma
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