scholarly journals Normothermic Machine Perfusion (NMP) Inhibits Proinflammatory Responses in the Liver and Promotes Regeneration

Hepatology ◽  
2019 ◽  
Vol 70 (2) ◽  
pp. 682-695 ◽  
Author(s):  
Wayel Jassem ◽  
Emmanuel Xystrakis ◽  
Yasmeen G. Ghnewa ◽  
Muhammed Yuksel ◽  
Oltin Pop ◽  
...  
Keyword(s):  
Machine Perfusion ◽  
Proinflammatory Responses ◽  
Normothermic Machine Perfusion

scholarly journals Human liver stem cell‐derived extracellular vesicles reduce injury in a model of normothermic machine perfusion of rat livers previously exposed to a prolonged warm ischemia

2021 ◽  
Vol 34 (9) ◽  
pp. 1607-1617
Author(s):  
Nicola De Stefano ◽  
Victor Navarro‐Tableros ◽  
Dorotea Roggio ◽  
Alberto Calleri ◽  
Federica Rigo ◽  
...  
Keyword(s):  
Stem Cell ◽  
Extracellular Vesicles ◽  
Human Liver ◽  
Warm Ischemia ◽  
Machine Perfusion ◽  
Normothermic Machine Perfusion ◽  
Rat Livers

scholarly journals Point‐of‐Care Assessment of DCD Livers During Normothermic Machine Perfusion in a Nonhuman Primate Model

2021 ◽  
Author(s):  
Samuel J. Kesseli ◽  
Jared N. Gloria ◽  
Nader Abraham ◽  
Samantha E. Halpern ◽  
Greta N. Cywinska ◽  
...  
Keyword(s):  
Nonhuman Primate ◽  
Point Of Care ◽  
Machine Perfusion ◽  
Nonhuman Primate Model ◽  
Primate Model ◽  
Care Assessment ◽  
Normothermic Machine Perfusion

Hyperspectral imaging for ex-vivo organ characterization during normothermic machine perfusion

2018 ◽  
Vol 17 (2) ◽  
pp. e767 ◽  
Author(s):  
W. Markgraf ◽  
M.W.W. Janssen ◽  
J. Lilienthal ◽  
P. Feistel ◽  
C. Thiele ◽  
...  
Keyword(s):  
Hyperspectral Imaging ◽  
Ex Vivo ◽  
Machine Perfusion ◽  
Normothermic Machine Perfusion

scholarly journals A novel, customized 3D-printed perfusion chamber for normothermic machine perfusion of the kidney

2018 ◽  
Vol 32 (1) ◽  
pp. 107-109 ◽  
Author(s):  
Ahmer Hameed ◽  
Suat Dervish ◽  
Natasha Rogers ◽  
Henry Pleass ◽  
Wayne Hawthorne
Keyword(s):  
Machine Perfusion ◽  
Perfusion Chamber ◽  
Normothermic Machine Perfusion ◽  
3D Printed

scholarly journals Porcine Liver Normothermic Machine Perfusion: Methodological Framework and Potential Pitfalls

2021 ◽  
Vol 8 (1) ◽  
pp. e1276
Author(s):  
Nicholas Gilbo ◽  
Tine Wylin ◽  
Veerle Heedfeld ◽  
Ina Jochmans ◽  
Jacques Pirenne ◽  
...  
Keyword(s):  
Machine Perfusion ◽  
Methodological Framework ◽  
Porcine Liver ◽  
Normothermic Machine Perfusion

scholarly journals The 24-hour normothermic machine perfusion of discarded human liver grafts

2017 ◽  
Vol 23 (2) ◽  
pp. 207-220 ◽  
Author(s):  
Thomas Vogel ◽  
Jens G. Brockmann ◽  
Alberto Quaglia ◽  
Alireza Morovat ◽  
Wayel Jassem ◽  
...  
Keyword(s):  
Human Liver ◽  
Machine Perfusion ◽  
Normothermic Machine Perfusion

MicroRNA antagonist therapy during normothermic machine perfusion of donor kidneys

2021 ◽  
Author(s):  
ER Thompson ◽  
A Sewpaul ◽  
R Figuereido ◽  
L Bates ◽  
SJ Tingle ◽  
...  
Keyword(s):  
Machine Perfusion ◽  
Antagonist Therapy ◽  
Normothermic Machine Perfusion

Recent advances in liver transplantation

2021 ◽  
pp. flgastro-2020-101425
Author(s):  
N Thomas Burke ◽  
James B Maurice ◽  
David Nasralla ◽  
Jonathan Potts ◽  
Rachel Westbrook
Keyword(s):  
Liver Transplantation ◽  
Survival Rates ◽  
Machine Perfusion ◽  
Allocation System ◽  
Life Saving ◽  
Opt Out ◽  
Normothermic Machine Perfusion ◽  
Marginal Grafts ◽  
Legislative Changes ◽  
The Uk

Liver transplant is a life-saving treatment with 1-year and 5-year survival rates of 90% and 70%, respectively. However, organ demand continues to exceed supply, such that many patients will die waiting for an available organ. This article reviews for the general gastroenterologist the latest developments in the field to reduce waiting list mortality and maximise utilisation of available organs. The main areas covered include legislative changes in organ donation and the new ‘opt-out’ systems being rolled out in the UK, normothermic machine perfusion to optimise marginal grafts, a new national allocation system to maximise benefit from each organ and developments in patient ‘prehabilitation’ before listing. Current areas of research interest, such as immunosuppression withdrawal, are also summarised.

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