scholarly journals Assessment of biopsy-proven liver fibrosis by two-dimensional shear wave elastography: An individual patient data-based meta-analysis

Hepatology ◽  
2017 ◽  
Vol 67 (1) ◽  
pp. 260-272 ◽  
Author(s):  
Eva Herrmann ◽  
Victor de Lédinghen ◽  
Christophe Cassinotto ◽  
Winnie C.-W. Chu ◽  
Vivian Y.-F. Leung ◽  
...  
Keyword(s):  
Liver Fibrosis ◽  
Shear Wave ◽  
Individual Patient Data ◽  
Meta Analysis ◽  
Shear Wave Elastography ◽  
Patient Data ◽  
Two Dimensional

scholarly journals Two-dimensional Shear-Wave Elastography and Conventional US: The Optimal Evaluation of Liver Fibrosis and Cirrhosis

Radiology ◽  
2015 ◽  
Vol 275 (1) ◽  
pp. 290-300 ◽  
Author(s):  
Jian Zheng ◽  
Huanyi Guo ◽  
Jie Zeng ◽  
Zeping Huang ◽  
Bowen Zheng ◽  
...  
Keyword(s):  
Liver Fibrosis ◽  
Shear Wave ◽  
Shear Wave Elastography ◽  
Two Dimensional ◽  
Optimal Evaluation

scholarly journals Diagnostic Performance of Two-dimensional Shear Wave Elastography in Advanced Liver Fibrosis: A Prospective Pathology-based Study

2020 ◽  
Author(s):  
Yao-Kuang Huang ◽  
Ren-Ching Wang ◽  
Sheng-Shun Yang ◽  
Shou-Wu Lee ◽  
Hsin-Ju Tsai ◽  
...  
Keyword(s):  
Chronic Hepatitis ◽  
Liver Fibrosis ◽  
Shear Wave ◽  
Liver Diseases ◽  
Diagnostic Performance ◽  
Shear Wave Elastography ◽  
Two Dimensional ◽  
Liver Disorders ◽  
Advanced Liver Fibrosis ◽  
Invasive Method

Abstract Studies for evaluating the diagnostic performance of two-dimensional Shear-wave Elastography (2D-SWE) in a patient cohort including various liver disorders, remain limited. We aimed to evaluate the validity of 2D-SWE in the diagnosis of advanced liver fibrosis amongst patients with various liver disorders. In this pathology-based study, patients who underwent a liver biopsy for various benign liver diseases were prospectively recruited during the period between February, 2017 and September, 2020. Data of 2D-SWE, Fibrosis-4 Index (FIB-4), and Aspartate Aminotransferase to Platelet Ratio Index (APRI) were simultaneously collected. The cut-off values for predicting advanced fibrosis, i.e. Metavir fibrosis stage ≥ F3, were determined using Receiver Operating Characteristic (ROC) analysis. The diagnostic performance was evaluated and then compared by Area Under the ROC (AUROC). In total, 95 patients were recruited for study analysis. The diagnostic performance of 2D-SWE was significantly superior to that of both FIB-4 (AUROC: 0.88, 95% confidence interval [CI]: 0.80-0.94; vs 0.72, 95%CI: 0.62-0.81; p=0.001) and APRI (AUROC: 0.88, 95%CI: 80-0.94; vs 0.76, 95%CI: 0.66-0.84; p=0.007). With an optimal cutoff value of 9.3 kPa, the sensitivity and specificity were 90.91% and 76.47%, respectively. In subgroup analysis, the AUROC of 2D-SWE was the highest when compared to that of FIB-4 and APRI in patients with chronic hepatitis B, chronic hepatitis C, fatty liver, and concurrent hepatitis. 2D-SWE can therefore be a valid non-invasive method in the detection of advanced liver fibrosis in various liver diseases.

scholarly journals 2D shear wave liver elastography by Aixplorer to detect portal hypertension in cirrhosis: An individual patient data meta‐analysis

2020 ◽  
Vol 40 (6) ◽  
pp. 1435-1446 ◽  
Author(s):  
Maja Thiele ◽  
Mie B. Hugger ◽  
Yongsoo Kim ◽  
Pierre‐Emmanuel Rautou ◽  
Laure Elkrief ◽  
...  
Keyword(s):  
Portal Hypertension ◽  
Shear Wave ◽  
Individual Patient Data ◽  
Meta Analysis ◽  
Patient Data ◽  
Liver Elastography

Performance and cutoffs for liver fibrosis staging of a two-dimensional shear wave elastography technique

2020 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Giovanna Ferraioli ◽  
Laura Maiocchi ◽  
Carolina Dellafiore ◽  
Carmine Tinelli ◽  
Elisabetta Above ◽  
...  
Keyword(s):  
Liver Fibrosis ◽  
Shear Wave ◽  
Shear Wave Elastography ◽  
Two Dimensional ◽  
Fibrosis Staging
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