Noninvasive tools and risk of clinically significant portal hypertension and varices in compensated cirrhosis: The “Anticipate” study

Hepatology ◽  
2016 ◽  
Vol 64 (6) ◽  
pp. 2173-2184 ◽  
Author(s):  
Juan G. Abraldes ◽  
Christophe Bureau ◽  
Horia Stefanescu ◽  
Salvador Augustin ◽  
Michael Ney ◽  
...  
Keyword(s):  
Portal Hypertension ◽  
Compensated Cirrhosis ◽  
Clinically Significant

scholarly journals Prognostic Markers in Patients with Cirrhosis and Portal Hypertension Who Have Not Bled

2011 ◽  
Vol 31 (3) ◽  
pp. 147-154 ◽  
Author(s):  
Maria Poca ◽  
Angela Puente ◽  
Isabel Graupera ◽  
Càndid Villanueva
Keyword(s):  
Portal Hypertension ◽  
Prognostic Value ◽  
Prognostic Markers ◽  
Transient Elastography ◽  
Serum Markers ◽  
Promising Technique ◽  
Prognostic Information ◽  
Compensated Cirrhosis ◽  
Clinically Significant ◽  
Complications Of Cirrhosis

Prognostic markers of compensated cirrhosis should mainly investigate factors involved with progression to decompensation because death in cirrhosis is related with decompensation. Portal hypertension plays a crucial role in the pathophysiology of most complications of cirrhosis. Accordingly, HVPGmonitoring has strong prognostic value. An HVPG ≥ 10 mmHg determines a significantly higher risk of developing decompensation. Esophageal varices also can develop when the HVPG is ≥ 10 mmHg, although an HVPG ≥ 12 mmHg is required for variceal bleeding to occur. Monitoring the changes induced by the treatment of portal hypertension on HVPG, provides strong prognostic information. In compensated cirrhosis hemodynamic response is appropriate when the HVPG decreased to <10 mmHg or by > 10% from baseline, because the incidence of complications such as bleeding or ascites significantly decrease when these targets are achieved. Whether serum markers, such as the FibroTest, they, may be valuable to predict decompensation should be established. Transient Elastography is a promising technique that has shown an excellent accuracy to detect severe portal hypertension. However, whether it can adequately determine clinically significant portal hypertension, and risk of developing varices and decompensation, should be established. Magnetic Resonance Elastography is also promising.

Su1696 SPLEEN STIFFNESS MEASUREMENTS (SSM) IN THE IDENTIFICATION OF CLINICALLY-SIGNIFICANT PORTAL HYPERTENSION (CSPH) IN PATIENTS WITH COMPENSATED CIRRHOSIS.

2020 ◽  
Vol 158 (6) ◽  
pp. S-1385
Author(s):  
Guillermo A. Ortiz ◽  
Chiara Palumbo ◽  
Mubarak W. Sayyar ◽  
Maya Balakrishnan ◽  
Arpan Mohanty ◽  
...  
Keyword(s):  
Portal Hypertension ◽  
Compensated Cirrhosis ◽  
Spleen Stiffness ◽  
Clinically Significant

Risk assessment of clinically significant portal hypertension by means of hepatosplenic volumetry in compensated cirrhosis

2020 ◽  
Vol 73 ◽  
pp. S742
Author(s):  
Mario Romero Cristóbal ◽  
Ana Clemente ◽  
Enrique Ramon Botella ◽  
Olga Ortega ◽  
Elena Velilla ◽  
...  
Keyword(s):  
Risk Assessment ◽  
Portal Hypertension ◽  
Compensated Cirrhosis ◽  
Clinically Significant

Ultrasound parameters in the prediction of clinically significant portal hypertension (CS-PHT) in compensated cirrhosis

2000 ◽  
Vol 118 (4) ◽  
pp. A968
Author(s):  
J. Ayala ◽  
M. Zalwin ◽  
C. Taylor ◽  
J. Bosch ◽  
R.J Groszmann ◽  
...  
Keyword(s):  
Portal Hypertension ◽  
Compensated Cirrhosis ◽  
Clinically Significant ◽  
Ultrasound Parameters

An unusual presentation of epigastric pain due to thrombophlebitis of a recanalised umbilical vein – case report

2019 ◽  
Vol 98 (8) ◽  
pp. 326-327 ◽  
Keyword(s):  
Liver Cirrhosis ◽  
Abdominal Pain ◽  
Case Report ◽  
Portal Hypertension ◽  
Liver Disease ◽  
Epigastric Pain ◽  
Umbilical Vein ◽  
History Of ◽  
Clinically Significant ◽  
Inflammatory Changes

Introduction: The umbilical vein can become recanalised due to portal hypertension in patients with liver cirrhosis but the condition is rarely clinically significant. Although bleeding from this enlarged vein is a known complication, the finding of thrombophlebitis has not been previously described. Case report: We report the case of a 62-year-old male with a history of liver cirrhosis due to alcoholic liver disease presenting to hospital with epigastric pain. A CT scan of the patient’s abdomen revealed a thrombus with surrounding inflammatory changes in a recanalised umbilical vein. The patient was managed conservatively and was discharged home the following day. Conclusion: Thrombophlebitis of a recanalised umbilical vein is a rare cause of abdominal pain in patients with liver cirrhosis.

scholarly journals Clinically significant portal hypertension in cirrhosis patients with COVID-19: Clinical characteristics and outcomes

2020 ◽  
Vol 81 (2) ◽  
pp. e178-e180 ◽  
Author(s):  
Furong Liu ◽  
Xin Long ◽  
Guibao Ji ◽  
Bixiang Zhang ◽  
Wanguang Zhang ◽  
...  
Keyword(s):  
Portal Hypertension ◽  
Clinical Characteristics ◽  
Clinically Significant
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