Mechanistic target of rapamycin complex 1 is an essential mediator of metabolic and mitogenic effects of fibroblast growth factor 19 in hepatoma cells

Zhi Yi Wan; Johann Shane Tian; Hayden Weng Siong Tan; Ai Lee Chow; Arthur Yi Loong Sim; Kenneth Hon Kim Ban; Yun Chau Long

doi:10.1002/hep.28639

Mechanistic target of rapamycin complex 1 is an essential mediator of metabolic and mitogenic effects of fibroblast growth factor 19 in hepatoma cells

Hepatology ◽

10.1002/hep.28639 ◽

2016 ◽

Vol 64 (4) ◽

pp. 1289-1301 ◽

Cited By ~ 14

Author(s):

Zhi Yi Wan ◽

Johann Shane Tian ◽

Hayden Weng Siong Tan ◽

Ai Lee Chow ◽

Arthur Yi Loong Sim ◽

...

Keyword(s):

Growth Factor ◽

Fibroblast Growth Factor ◽

Hepatoma Cells ◽

Target Of Rapamycin ◽

Fibroblast Growth ◽

Mechanistic Target Of Rapamycin ◽

Fibroblast Growth Factor 19

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Fibroblast growth factor 19 meets mammalian target of rapamycin: A mitogenic Tête-à-Tête under consideration

Hepatology ◽

10.1002/hep.28691 ◽

2016 ◽

Vol 64 (4) ◽

pp. 1028-1030 ◽

Cited By ~ 1

Author(s):

Elisabeth Krones ◽

Martin Wagner

Keyword(s):

Growth Factor ◽

Fibroblast Growth Factor ◽

Mammalian Target Of Rapamycin ◽

Target Of Rapamycin ◽

Fibroblast Growth ◽

Fibroblast Growth Factor 19

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Fibroblast Growth Factor 19 (FGF-19)– Verringerte postprandiale Serumspiegel bei nicht Adipösen mit nichtalkoholischer Fettlebererkrankung (NAFLD)

Zeitschrift für Gastroenterologie ◽

10.1055/s-0030-1269540 ◽

2011 ◽

Vol 49 (01) ◽

Author(s):

D Friedrich ◽

F Lammert

Keyword(s):

Growth Factor ◽

Fibroblast Growth Factor ◽

Fibroblast Growth ◽

Fibroblast Growth Factor 19

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Vitamin A derivatives regulate fibroblast growth factor 19 expression in human enterocytes

Zeitschrift für Gastroenterologie ◽

10.1055/s-0035-1558901 ◽

2015 ◽

Vol 53 (09) ◽

Author(s):

D Jahn ◽

D Sutor ◽

J Schmitt ◽

HM Hermanns ◽

A Geier

Keyword(s):

Growth Factor ◽

Vitamin A ◽

Fibroblast Growth Factor ◽

Fibroblast Growth ◽

Fibroblast Growth Factor 19

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The Influence of the Duration of Type 2 Diabetes Mellitus on the Activity of Fibroblast Growth Factor-19 in Patients with Concomitant Biliary Pathology

Ukraïnsʹkij žurnal medicini bìologìï ta sportu ◽

10.26693/jmbs05.01.219 ◽

2020 ◽

Vol 5 (1) ◽

pp. 219-224

Author(s):

G. Yu. Tymoshenko ◽

Keyword(s):

Diabetes Mellitus ◽

Type 2 Diabetes ◽

Type 2 Diabetes Mellitus ◽

Growth Factor ◽

Fibroblast Growth Factor ◽

Fibroblast Growth ◽

Biliary Pathology ◽

Fibroblast Growth Factor 19

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Orphan designation: Variant of recombinant human fibroblast growth factor 19, Treatment of primary biliary cirrhosis

Case Medical Research ◽

10.31525/cmr-1336905 ◽

2019 ◽

Author(s):

Keyword(s):

Growth Factor ◽

Primary Biliary Cirrhosis ◽

Fibroblast Growth Factor ◽

Human Fibroblast ◽

Biliary Cirrhosis ◽

Fibroblast Growth ◽

Orphan Designation ◽

Fibroblast Growth Factor 19

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Faculty Opinions recommendation of Fibroblast growth factor 19 increases metabolic rate and reverses dietary and leptin-deficient diabetes.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.723616919.793502469 ◽

2014 ◽

Author(s):

Michael Schwartz ◽

Jarrad Scarlett

Keyword(s):

Growth Factor ◽

Metabolic Rate ◽

Fibroblast Growth Factor ◽

Fibroblast Growth ◽

Fibroblast Growth Factor 19

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Faculty Opinions recommendation of Engineered fibroblast growth factor 19 reduces liver injury and resolves sclerosing cholangitis in Mdr2-deficient mice.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.725817957.793516311 ◽

2016 ◽

Author(s):

Michael Trauner ◽

Martin Wagner

Keyword(s):

Growth Factor ◽

Liver Injury ◽

Fibroblast Growth Factor ◽

Sclerosing Cholangitis ◽

Fibroblast Growth ◽

Fibroblast Growth Factor 19 ◽

Deficient Mice

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Faculty Opinions recommendation of Fibroblast growth factor 19 regulates skeletal muscle mass and ameliorates muscle wasting in mice.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.727746955.793533652 ◽

2017 ◽

Author(s):

Sakae Tanaka

Keyword(s):

Skeletal Muscle ◽

Growth Factor ◽

Fibroblast Growth Factor ◽

Muscle Mass ◽

Skeletal Muscle Mass ◽

Muscle Wasting ◽

Fibroblast Growth ◽

Fibroblast Growth Factor 19

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Fibroblast Growth Factor 19–Mediated Up‐regulation of SYR‐Related High‐Mobility Group Box 18 Promotes Hepatocellular Carcinoma Metastasis by Transactivating Fibroblast Growth Factor Receptor 4 and Fms‐Related Tyrosine Kinase 4

Hepatology ◽

10.1002/hep.30951 ◽

2020 ◽

Vol 71 (5) ◽

pp. 1712-1731 ◽

Cited By ~ 7

Author(s):

Jie Chen ◽

Feng Du ◽

Yunzhi Dang ◽

Xiaowei Li ◽

Meirui Qian ◽

...

Keyword(s):

Hepatocellular Carcinoma ◽

Growth Factor ◽

Tyrosine Kinase ◽

Fibroblast Growth Factor ◽

Fibroblast Growth Factor Receptor ◽

Growth Factor Receptor ◽

High Mobility ◽

Fibroblast Growth ◽

Carcinoma Metastasis ◽

Fibroblast Growth Factor 19

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OC-036 Stimulated expression of ileal fibroblast growth factor 19 by bile acids is impaired in patients with primary and secondary bile acid diarrhoea

Gut ◽

10.1136/gutjnl-2015-309861.36 ◽

2015 ◽

Vol 64 (Suppl 1) ◽

pp. A19.1-A19

Author(s):

JD Nolan ◽

RN Appleby ◽

GK Madhan ◽

IM Johnston ◽

K Sarah ◽

...

Keyword(s):

Bile Acid ◽

Growth Factor ◽

Bile Acids ◽

Fibroblast Growth Factor ◽

Fibroblast Growth ◽

Secondary Bile Acid ◽

Fibroblast Growth Factor 19

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