Patient-derived mouse xenografts from pediatric liver cancer predict tumor recurrence and advise clinical management

Hepatology ◽  
2016 ◽  
Vol 64 (4) ◽  
pp. 1121-1135 ◽  
Author(s):  
Delphine Nicolle ◽  
Monique Fabre ◽  
Marina Simon-Coma ◽  
Aurore Gorse ◽  
Roland Kappler ◽  
...  
Keyword(s):  
Liver Cancer ◽  
Clinical Management ◽  
Tumor Recurrence ◽  
Pediatric Liver ◽  
Predict Tumor Recurrence

scholarly journals Widespread Molecular Alterations Present in Stage I Non-Small Cell Lung Carcinoma Fail to Predict Tumor Recurrence

2003 ◽  
Vol 16 (1) ◽  
pp. 28-34 ◽  
Author(s):  
Fabien K Baksh ◽  
Sanja Dacic ◽  
Sydney D Finkelstein ◽  
Patricia A Swalsky ◽  
Siva Raja ◽  
...  
Keyword(s):  
Lung Carcinoma ◽  
Tumor Recurrence ◽  
Small Cell Lung Carcinoma ◽  
Small Cell ◽  
Stage I ◽  
Small Cell Lung ◽  
Cell Lung Carcinoma ◽  
Molecular Alterations ◽  
Predict Tumor Recurrence

scholarly journals A Multidisciplinary Approach to Pediatric Liver Cancer Decreases Perioperative Complications and Improves Outcomes.

2020 ◽  
Author(s):  
Richard Whitlock ◽  
Sarah Jane Commander ◽  
Tu-Anh Ha ◽  
Huirong Zhu ◽  
Jorge Portuondo ◽  
...  
Keyword(s):  
Liver Cancer ◽  
Multidisciplinary Approach ◽  
Perioperative Complications ◽  
Pediatric Liver

scholarly journals Integrated genomic analysis identifies driver genes and cisplatin-resistant progenitor phenotype in pediatric liver cancer

2021 ◽  
pp. candisc.1809.2020
Author(s):  
Theo Z Hirsch ◽  
Jill Pilet ◽  
Guillaume Morcrette ◽  
Amelie Roehrig ◽  
Benedict JE Monteiro ◽  
...  
Keyword(s):  
Liver Cancer ◽  
Genomic Analysis ◽  
Driver Genes ◽  
Pediatric Liver

Are False-Positive Urine Markers for the Detection of Bladder Carcinoma Really Wrong or Do They Predict Tumor Recurrence?

2003 ◽  
Vol 43 (2) ◽  
pp. 146-151 ◽  
Author(s):  
Martin G Friedrich ◽  
Angelika Hellstern ◽  
Marieta I Toma ◽  
Peter Hammerer ◽  
Hartwig Huland
Keyword(s):  
Bladder Carcinoma ◽  
False Positive ◽  
Tumor Recurrence ◽  
Positive Urine ◽  
Predict Tumor Recurrence ◽  
Urine Markers

scholarly journals Liver Transplantation for Pediatric Liver Cancer

Cancers ◽  
2020 ◽  
Vol 12 (3) ◽  
pp. 720 ◽  
Author(s):  
Rakesh Sindhi ◽  
Vinayak Rohan ◽  
Andrew Bukowinski ◽  
Sameh Tadros ◽  
Jean de Ville de Goyet ◽  
...  
Keyword(s):  
Liver Transplantation ◽  
Liver Cancer ◽  
Liver Tumors ◽  
Current Knowledge ◽  
Tumor Staging ◽  
Steady Increase ◽  
Malignant Rhabdoid Tumor ◽  
Diagnostic Uncertainty ◽  
Pediatric Liver ◽  
Improvement In Survival

Unresectable hepatocellular carcinoma (HCC) was first removed successfully with total hepatectomy and liver transplantation (LT) in a child over five decades ago. Since then, children with unresectable liver cancer have benefitted greatly from LT and a confluence of several equally important endeavors. Regional and trans-continental collaborations have accelerated the development and standardization of chemotherapy regimens, which provide disease control to enable LT, and also serve as a test of unresectability. In the process, tumor histology, imaging protocols, and tumor staging have also matured to better assess response and LT candidacy. Significant trends include a steady increase in the incidence of and use of LT for hepatoblastoma, and a significant improvement in survival after LT for HCC with each decade. Although LT is curative for most unresectable primary liver sarcomas, such as embryonal sarcoma, the malignant rhabdoid tumor appears relapse-prone despite chemotherapy and LT. Pediatric liver tumors remain rare, and diagnostic uncertainty in some settings can potentially delay treatment or lead to the selection of less effective chemotherapy. We review the current knowledge relevant to diagnosis, LT candidacy, and post-transplant outcomes for these tumors, emphasizing recent observations made from large registries or larger series.

61 A panel of pediatric liver cancer patient-derived xenografts to improve stratification of children with hepatoblastoma

2014 ◽  
Vol 50 ◽  
pp. 25
Author(s):  
M. Fabre ◽  
D. Nicolle ◽  
A. Gorse ◽  
O. Déas ◽  
C. Mussini ◽  
...  
Keyword(s):  
Liver Cancer ◽  
Cancer Patient ◽  
Pediatric Liver ◽  
Liver Cancer Patient
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