scholarly journals Central obesity induces a greater risk of hepatocellular carcinoma than general obesity

Hepatology ◽  
2015 ◽  
Vol 62 (3) ◽  
pp. 979-980 ◽  
Author(s):  
Qing Pang ◽  
Jing Yao Zhang ◽  
Kai Qu ◽  
Si Dong Song ◽  
Su Shun Liu ◽  
...  
Author(s):  
Julianty Pradono ◽  
Sintawati Sintawati

Background<br />Obesity and hypertension are independent risk factors in the increasing prevalence of non-communicable diseases. The proportion of obesity in Indonesia has increased in the last 5 years according to the National Health Survey. The purpose of this research was to obtain the contribution of obesity toward hypertension in the age group of 18 years and above.<br /><br />Methods<br />An observational study of cross-sectional design was conducted using the National Basic Health Research 2013 population data. The total sample of subjects was 2,741,297 from 33 provinces in Indonesia. Data were collected through interviews, blood pressure measurement, and anthropometry. Analysis of categorical data was by means of the chi-square statistical test, followed by calculation of the attributable fraction in the population, and analysis of factors influencing the impact fraction.<br /><br />Results<br />The prevalence of general obesity (BMI&gt;25 kg/m2) was 31.5% in males and 48.0% in females, while central obesity was 20.9% in males and 42.5% in females. In females with general obesity the risk of hypertension was 1.84 (95% CI: 1.82-1.86) times higher than in those with normal BMI. If general obesity and central obesity can be reduced, the prevalence of hypertension may be reduced by 2.9% in males and by 12.2% in females.<br /><br />Conclusion<br />The prevalence of hypertension in the age group of 18 years or more can be reduced by 2.9% in males and by 12.2% in females, by overcoming the contribution of obesity. Therefore efforts should be geared towards promoting healthy eating habits and maintaining a healthy weight through health education.


Author(s):  
Vida Mozaffari-Khosravi ◽  
Masoud Mirzaei ◽  
Hassan Mozaffari-Khosravi

Introduction: Metabolic syndrome is a series of disorders such as central obesity, hypertriglyceridemia, decreasing HDL, abnormal blood glucose and hypertension that ultimately lead to the risk of cardiovascular disease, diabetes and other problems. The aim of this study was to determine the prevalence of this syndrome among adults in Yazd. Methods: This study was performed using the data of the recruitment phase of "Yazd Health Study" (YaHS). More than 10,000 residents (aged 20-69 years) of Yazd Greater Area have participated in this prospective cohort study. Lifestyle data, disease history, and blood tests have been recorded. Sampling was cluster random based on the postal code of the residents of Yazd Greater Area. Out of the 10,000 participants in the study, approximately 4,000 people gave blood samples to the lab in the first phase and their data were used to calculate the syndrome. Metabolic syndrome was defined based on the ATP III criteria. Data were analyzed by SPSS Version 16. Results: The overall prevalence of syndrome was 33.3%. The prevalence had a significant relationship with age, age over 40 years, reaching to the highest level of over 50%. The prevalence in women was 39.9%, more than men, with 25.9%. Frequency of abnormal components of the syndrome was respectively waist circumference or abdominal obesity (47.1%), diastolic or systolic blood pressure (43.7%), triglyceride (41.6%), HDL (39.5%) and fasting blood glucose (21.7). 67.5% and 91.7% of those with syndrome were obese or overweight, respectively. Conclusion: The study showed that the prevalence of metabolic syndrome, especially in women and those over 50 years old, is higher than other studies. General obesity, central obesity and hypertension are the most important components of metabolic syndrome in Yazd, which requires proper interventions.


Nutrients ◽  
2020 ◽  
Vol 12 (3) ◽  
pp. 751
Author(s):  
Marta Lonnie ◽  
Lidia Wadolowska ◽  
Elzbieta Bandurska-Stankiewicz

The aim of this study was to examine the associations of dietary-lifestyle patterns (DLPs) with adiposity and metabolic abnormalities in adult Polish men that were under 40. The cross-sectional study included 358 men that were 19–40-year-old. Dietary and lifestyle data were collected with multicomponent food frequency questionnaire (KomPAN®). DPLs were derived with Principal Component Analysis (PCA) using 25 dietary and six lifestyle as the input variables. Adiposity was determined with the use of: overweight (body mass index 25–29.9 kg/m2), central obesity (waist-to-height ratio ≥ 0.5), general obesity (body fat ≥ 25%), excessive visceral fat tissue (≥ median), and increased skeletal muscle mass (≥ median). The metabolic abnormalities were characterised by elevated: fasting blood glucose (FBG ≥ 100 mg/dL), triglycerides (TG ≥ 150 mg/dL), total cholesterol (TC ≥ 200 mg/dL), or systolic or diastolic blood pressure (≥ 130 or ≥ 85 mmHg, respectively). Four PCA-driven DLPs were derived and labelled accordingly to the most characteristic dietary or lifestyle behaviours that were correlated with each pattern. Multivariate logistic regression revealed that higher adherence (upper vs. bottom tertile as referent) to “Protein food, fried-food, and recreational physical activity” pattern was associated with higher odds of overweight and increased skeletal muscle mass, and lower odds of: general obesity, excessive visceral fat tissue, and elevated TC. Higher adherence to “Healthy diet, active, past smokers” pattern was associated with higher odds of overweight and lower odds of: general obesity, excessive visceral fat tissue, and elevated FBG. Higher adherence to “Sandwiches and convenient diet” pattern was associated with higher odds of: central obesity, general obesity, excessive visceral fat tissue, elevated TC, elevated TG, occurrence at least two metabolic abnormalities, and lower odds of increased skeletal muscle mass. A higher adherence to “Fast foods and stimulants” pattern was associated with higher odds of central obesity, general obesity, excessive visceral fat tissue, and lower odds of increased skeletal muscle mass. The interrelations between diet and lifestyle behaviours were reflected in three out of four patterns. Healthy diet attempts combined with active lifestyle was associated with reduced risk of adiposity and metabolic abnormalities despite some unhealthy components, like former smoking or fried-food consumption. In contrary, patterns that were composed of undesirable dietary behaviours solely, as well as poor diet combined with stimulant use, were associated with higher adiposity and worse metabolic health, despite the relatively young age of the study participants. Accurate mapping of dietary-lifestyle behaviours can serve as a tool for formulating evidence-based recommendations.


2020 ◽  
Vol 2 (3) ◽  
pp. 118-127
Author(s):  
Septiyanti Septiyanti ◽  
Seniwati Seniwati

Obesity is a problem in various parts of the world where its prevalence is increasing rapidly, both in developed and developing countries Obesity can occur because of an imbalance between the energy from the food that comes in, which is greater than the energy used by the body. This study aimed to see the characteristics of obesity and central obesity in adult society in urban areas of Indonesia. This study used a cross-sectional study, by analyzing advanced data on Basic Health Research (Riskesdas) in the biomedical field. The results of this study indicated that in general obesity and central obesity increase with age, with the highest prevalence being at the age of 40-59 years. Both obesity and central obesity were more prevalent in female subjects. Obesity and central obesity were also more common among subjects who graduated from high school and who work as housewives. Subjects of obesity and central obesity experienced more abnormalities in biomedical examination than those with normal BMI and abdominal circumference. For this reason, it is advisable to maintain a normal BMI and abdominal circumference, especially for adults. This study proves that there are significant differences in biomedical examination in those who are obese and not obese.


2021 ◽  
Vol 50 (Supplement_1) ◽  
Author(s):  
Yingying Wang

Abstract Background Obesity and homocysteine (Hcy) are two important risk factors for cardiovascular disease (CVD); however, there were conflicting results for the relationship between them. Our study is to explore the associations of general and central obesity with hyperhomocysteinemia (HHcy) in middle-aged women. Methods The current analysis was based on data from 11007 women aged 40-60 years. Height, weight, and waist circumference (WC) were measured and serum homocysteine was determined. Multiple logistic regression models were used to assess the associations of the risk of hyperhomocysteinemia (HHcy, Hcy&gt;15μmol/L) with BMI and WC. Results 13.71% women had HHcy. The prevalences of BMI-based general obesity and WC-based central obesity were 11.17% and 22.88%, respectively. Compared with non-obese women, the mean serum Hcy concentration was significantly higher in WC-based central obese women (P = 0.002), but not in BMI-based general obese women (P &gt; 0.05). In the multiple logistic regression models, central obesity was positively related to the risk of HHcy (OR = 1.30, 95%CI=1.10 to 1.52), while general obesity was inversely related to the risk of HHcy (OR = 0.82, 95%CI=0.72 to 0.93 and OR = 0.71,95% CI = 0.57 to 0.89). Conclusions Central obesity was positively, while general obesity was negatively related to the risk of HHcy. Menopause showed no effect modification on these associations. Key messages Homocysteine; Central obesity; Menopause; Cardiovascular Disease


2005 ◽  
Vol 75 (4) ◽  
pp. 297-304 ◽  
Author(s):  
Azadbakht ◽  
Mirmiran ◽  
Shiva ◽  
Azizi

Aims: To determine the prevalence and associations of general and central obesity in adults residing in district 13 of Tehran and to examine the associations of obesity with certain factors. Design: Population-based cross sectional study. Setting: Tehran, the capital of Iran. Subjects: A total of 9984 subjects (4164 men and 5820 women) aged 20–70 years. Methods: Demographic data were collected and anthropometric indices including weight, height, and waist and hip circumference were measured, according to standard protocols. Dietary intake was assessed by means of two 24-hour dietary recall forms. To determine the prevalence and association of general and central obesity, the suggested cut-off for Tehranian people, adjusted for their age group, was used. A body mass index (BMI) of ≥ 24 for men and ≥ 25 for women was used to determine the characteristic of obesity . Central obesity was determined as a waist-hip ratio (WHR) of > 0.86 for men and WHR ≥ 0.78 for women. To determine the associations between general and central obesity and other factors, logistic regression was used. Results: The means of BMI, waist circumference (WC), and WHR were 25.8 ± 4.1 kg/m2, 88.3 ± 11.4 cm, and 0.91 ± 0.07 in men and 27.3 ± 5.4 kg/m2, 87.5 ± 12.9 cm, and 0.83 ± 0.08 in women, respectively. Obesity and central obesity were higher in women than in men; 67% vs. 29% for obesity and 93% vs. 74.1% for central obesity, respectively. Illiteracy (OR = 1.65; 95% CI = 1.13–2.41 in men; OR = 1.87, 95% CI = 1.59–2.21 in women), marriage (OR = 3.84, 95% CI = 3.63–4.29 in men; OR = 3.20, 95% CI = 3.63–4.19 in women), and very low physical activity (OR = 1.35, 95% CI = 1.09–1.53 in men; OR = 1.39, 95% CI = 1.10–1.76 in women) were factors associated with obesity. The risk of being centrally obese for men in the fourth quartile of legumes intake was lower than men in other quartiles (p < 0.05). Women in the first quartile of dairy consumption had the highest risk of being generally and centrally obese (OR = 2.16, 95% CI = 1.72–2.48 for general obesity and OR = 3.01, 95% CI = 2.36-3.67 for central obesity). The risk of obesity for women in the fourth quartile of energy and saturated fatty acid consumption was higher than for those in the first quartile (OR = 2.69, 95% CI = 2.39–3.11 for energy and OR = 1.36, 95% CI= 1.10–1.64 for saturated fatty acids). The risk of being centrally obese was higher for women in the first quartile of protein intake compared with women in the fourth quartile (OR = 1.71, 95% CI = 1.02–2.32). Conclusions: The results from this national population-based study in Iran show high prevalence of obesity in Tehranian adults. The strong associations between obesity and certain life style factors confirm the necessity of multifactorial intervention.


2021 ◽  
Vol 9 (1) ◽  
pp. 211-221
Author(s):  
Astha Astha ◽  
Bindu Krishnan ◽  
Anup Kharde

Over the past few decades there has been an increase in the central or abdominal obesity. Endothelial dysfunction, insulin resistance with metabolic syndrome and a higher cardiometabolic risk are directly linked to abdominal obesity. A better understanding of the epidemiology of obesity would provide insights to its mitigation. This cross sectional study was designed to identify Central obesity, General obesity and Normal Weight central obesity among young adults using the following surrogate markers Waist circumference (WC), Waist hip ratio (WHR), Waist height ratio (WtHR) and BMI. After due informed written consent, 300 young adults with equal representation of both sexes (150 each) studying MBBS, Dentistry and Physiotherapy stream in a private university were selected. Various anthropometric measures like weight, hip circumference and waist circumference and height were measured according to WHO STEPS instrument. BMI based on Asia- Pacific cut -off values was used to define general obesity. Central obesity was defined by a Waist Circumference of  80 cm in females and  90 cm in male’s .For waist to height ratio a value of  0.5 in both genders was used. For waist to hip ratio the cut off value used was 0.85 in females and 0.90 in males. An individual with normal weight according to BMI but having central obesity fits into Normal Weight Central obesity category. Average age of the participants was 20.6 1.31 years. General Obesity was more among males with 46% prevalence as compared to 25.33%among females. In contrast, the prevalence of central obesity was more among females. The prevalence of Normal weight central obesity was more among females, varying from 4% to 17% using different types of anthropometric measures for central obesity. A high positive correlation was observed between BMI with WC, WtHR and WHR. (p=0.0001) Current practice of taking only BMI into consideration for defining obesity in our country needs serious re-evaluation considering the increasing prevalence of abdominal obesity and its long term impact.


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