scholarly journals Excess mortality on the liver transplant waiting list: Unintended policy consequences and model for End-Stage Liver Disease (MELD) inflation

Hepatology ◽  
2014 ◽  
Vol 61 (1) ◽  
pp. 285-291 ◽  
Author(s):  
Patrick Grant Northup ◽  
Nicolas Michael Intagliata ◽  
Neeral Lalit Shah ◽  
Shawn Joseph Pelletier ◽  
Carl Lansing Berg ◽  
...  
Keyword(s):  
Liver Disease ◽  
Liver Transplant ◽  
Excess Mortality ◽  
Waiting List ◽  
End Stage Liver Disease ◽  
Liver Transplant Waiting List ◽  
End Stage

339 Outcomes of Patients With END-Stage Liver Disease on Dialysis for More Than 6 Weeks on the Liver Transplant Waiting List

2010 ◽  
Vol 138 (5) ◽  
pp. S-784
Author(s):  
Ayse L. Mindikoglu ◽  
Laurence S. Magder ◽  
Stephen L. Seliger ◽  
Jean-Pierre Raufman ◽  
Charles D. Howell
Keyword(s):  
Liver Disease ◽  
Liver Transplant ◽  
Waiting List ◽  
End Stage Liver Disease ◽  
Liver Transplant Waiting List ◽  
End Stage

Validation of the five-variable Model for End-stage Liver Disease (5vMELD) for prediction of mortality on the liver transplant waiting list

2013 ◽  
Vol 34 (8) ◽  
pp. 1176-1183 ◽  
Author(s):  
Robert P. Myers ◽  
Puneeta Tandon ◽  
Michael Ney ◽  
Glenda Meeberg ◽  
Peter Faris ◽  
...  
Keyword(s):  
Liver Disease ◽  
Liver Transplant ◽  
Waiting List ◽  
Variable Model ◽  
End Stage Liver Disease ◽  
Prediction Of Mortality ◽  
Liver Transplant Waiting List ◽  
End Stage

scholarly journals Multidrug-Resistant Bacteria and Disease Progression in Patients with End-Stage Liver Disease and after Liver Transplantation

2019 ◽  
Vol 28 (3) ◽  
pp. 303-310 ◽  
Author(s):  
Kilian Friedrich ◽  
Jessica Krempl ◽  
Shigehiko Schamoni ◽  
Theresa Hippchen ◽  
Jan Pfeiffenberger ◽  
...  
Keyword(s):  
Liver Disease ◽  
Liver Transplant ◽  
Multidrug Resistant ◽  
Waiting List ◽  
Resistant Bacteria ◽  
Actuarial Survival ◽  
End Stage Liver Disease ◽  
Increased Risk ◽  
End Stage ◽  
The Impact

Background: Multidrug-resistant (MDR) pathogens represent an emerging challenge in end-stage liver disease and in liver transplant recipients. Methods: We evaluated the impact of MDR bacteria upon clinical outcomes in patients with end-stage liver disease (n = 777) at the time of enrollment on the liver transplant (LTx) waiting list, after first LTx (n = 645), and after second LTx (n = 128). Results: Colonization/infection with MDR bacteria was present in 72/777 patients on the waiting list, in 98/645 patients at first LTx, and in 46/128 patients at second LTx. While on the LTx waiting list, the time until first hydropic decompensation (p = 0.021), hepatic encephalopathy (p < 0.001) and hepatorenal syndrome (p < 0.001) was reduced in the presence of MDR bacteria, which remained an independent risk factor of poor survival in multivariate analysis (p < 0.001). Following first and second liver transplant, MDR bacteria were associated with an increased risk of infection-related deaths (first LTx: p < 0.001; second LTx: p = 0.037) and reduced actuarial survival (first LTx: p < 0.001; second LTx: p = 0.046). Conclusions: We showed that MDR pathogens are associated with poor outcomes before, after first and after recurrent LTx.

The Case of the Criminal Liver

2011 ◽  
Vol 20 (1) ◽  
pp. 143-143 ◽  
Author(s):  
RUCHIKA MISHRA
Keyword(s):  
Liver Disease ◽  
Hepatitis C ◽  
Liver Transplant ◽  
Chinese American ◽  
Chronic Fatigue ◽  
Meld Score ◽  
Waiting List ◽  
End Stage Liver Disease ◽  
Speed Up ◽  
End Stage

Mr. C was a 62-year-old Chinese-American man suffering from end stage liver disease secondary to Hepatitis C. While on the waiting list for a liver, he was told that his current condition and MELD score were not advanced enough to expect a liver transplant for several years. Because of his chronic fatigue, he asked if there was any way to speed up the process but was told that was not possible.

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