scholarly journals M2 Kupffer cells promote M1 Kupffer cell apoptosis: A protective mechanism against alcoholic and nonalcoholic fatty liver disease

Hepatology ◽  
2013 ◽  
Vol 59 (1) ◽  
pp. 130-142 ◽  
Author(s):  
Jinghong Wan ◽  
Merieme Benkdane ◽  
Fatima Teixeira-Clerc ◽  
Stéphanie Bonnafous ◽  
Alexandre Louvet ◽  
...  
Keyword(s):  
Liver Disease ◽  
Fatty Liver ◽  
Nonalcoholic Fatty Liver Disease ◽  
Kupffer Cell ◽  
Kupffer Cells ◽  
Cell Apoptosis ◽  
Fatty Liver Disease ◽  
Protective Mechanism ◽  
Nonalcoholic Fatty Liver

scholarly journals Kupffer cells: increasingly significant role in nonalcoholic fatty liver disease

2014 ◽  
Vol 13 (5) ◽  
pp. 489-495 ◽  
Author(s):  
Zhang Wenfeng ◽  
Wu Yakun ◽  
Mu Di ◽  
Gong Jianping ◽  
Wu Chuanxin ◽  
...  
Keyword(s):  
Liver Disease ◽  
Fatty Liver ◽  
Nonalcoholic Fatty Liver Disease ◽  
Significant Role ◽  
Kupffer Cells ◽  
Fatty Liver Disease ◽  
Nonalcoholic Fatty Liver

scholarly journals In vivo assessment of liver cell apoptosis as a novel biomarker of disease severity in nonalcoholic fatty liver disease

Hepatology ◽  
2006 ◽  
Vol 44 (1) ◽  
pp. 27-33 ◽  
Author(s):  
Anna Wieckowska ◽  
Nizar N. Zein ◽  
Lisa M. Yerian ◽  
A. Rocio Lopez ◽  
Arthur J. McCullough ◽  
...  
Keyword(s):  
Liver Disease ◽  
Fatty Liver ◽  
Nonalcoholic Fatty Liver Disease ◽  
Disease Severity ◽  
Liver Cell ◽  
Cell Apoptosis ◽  
Fatty Liver Disease ◽  
Nonalcoholic Fatty Liver ◽  
In Vivo Assessment

824 Proinflammatory Effects on Monocytes and Kupffer Cells in Patients With Nonalcoholic Fatty Liver Disease (NAFLD)

2012 ◽  
Vol 142 (5) ◽  
pp. S-929
Author(s):  
Maria E. Inzaugarat ◽  
Marianela Ballesta ◽  
Placida Baz ◽  
Dario V. Fontana ◽  
Milagros L. Linares ◽  
...  
Keyword(s):  
Liver Disease ◽  
Fatty Liver ◽  
Nonalcoholic Fatty Liver Disease ◽  
Kupffer Cells ◽  
Fatty Liver Disease ◽  
Nonalcoholic Fatty Liver

scholarly journals How Inflammation Impinges on NAFLD: A Role for Kupffer Cells

2015 ◽  
Vol 2015 ◽  
pp. 1-11 ◽  
Author(s):  
Nádia Duarte ◽  
Inês C. Coelho ◽  
Rita S. Patarrão ◽  
Joana I. Almeida ◽  
Carlos Penha-Gonçalves ◽  
...  
Keyword(s):  
Insulin Resistance ◽  
Liver Disease ◽  
Fatty Liver ◽  
Nonalcoholic Fatty Liver Disease ◽  
Kupffer Cells ◽  
Fatty Liver Disease ◽  
Present Knowledge ◽  
Nonalcoholic Fatty Liver ◽  
Adults And Children ◽  
Fat Liver

Nonalcoholic fatty liver disease (NAFLD) is rapidly becoming the most prevalent cause of liver disease worldwide and afflicts adults and children as currently associated with obesity and insulin resistance. Even though lately some advances have been made to elucidate the mechanism and causes of the disease much remains unknown about NAFLD. The aim of this paper is to discuss the present knowledge regarding the pathogenesis of the disease aiming at the initial steps of NAFLD development, when inflammation impinges on fat liver deposition. At this stage, the Kupffer cells attain a prominent role. This knowledge becomes subsequently relevant for the development of future diagnostic, prevention, and therapeutic options for the management of NAFLD.

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