The immunobiology of colitis and cholangitis in interleukin-23p19 and interleukin-17a deleted dominant negative form of transforming growth factor beta receptor type ii mice

Yugo Ando; Guo-Xiang Yang; Masanobu Tsuda; Kazuhito Kawata; Weici Zhang; Takahiko Nakajima; Koichi Tsuneyama; Patrick Leung; Zhe-Xiong Lian; Kazuichi Okazaki; William M. Ridgway; Gary L. Norman; Aftab A. Ansari; Xiao-Song He; Ross L. Coppel; M. Eric Gershwin

doi:10.1002/hep.25803

The immunobiology of colitis and cholangitis in interleukin-23p19 and interleukin-17a deleted dominant negative form of transforming growth factor beta receptor type ii mice

Hepatology ◽

10.1002/hep.25803 ◽

2012 ◽

Vol 56 (4) ◽

pp. 1418-1426 ◽

Cited By ~ 31

Author(s):

Yugo Ando ◽

Guo-Xiang Yang ◽

Masanobu Tsuda ◽

Kazuhito Kawata ◽

Weici Zhang ◽

...

Keyword(s):

Growth Factor ◽

Transforming Growth Factor Beta ◽

Transforming Growth Factor ◽

Dominant Negative ◽

Receptor Type ◽

Type Ii ◽

Interleukin 17A ◽

Dominant Negative Form ◽

Growth Factor Beta ◽

Negative Form

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Endogenous interleukin-22 protects against inflammatory bowel disease but not autoimmune cholangitis in dominant negative form of transforming growth factor beta receptor type II mice

Clinical & Experimental Immunology ◽

10.1111/cei.12806 ◽

2016 ◽

Vol 185 (2) ◽

pp. 154-164 ◽

Cited By ~ 7

Author(s):

G.-X. Yang ◽

Y. Sun ◽

K. Tsuneyama ◽

W. Zhang ◽

P. S. C. Leung ◽

...

Keyword(s):

Transforming Growth Factor Beta ◽

Transforming Growth Factor ◽

Dominant Negative ◽

Type Ii ◽

Autoimmune Cholangitis ◽

Interleukin 22 ◽

Dominant Negative Form ◽

Inflammatory Bowel ◽

Growth Factor Beta ◽

Negative Form

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Faculty Opinions recommendation of Deletion of interleukin-6 in mice with the dominant negative form of transforming growth factor beta receptor II improves colitis but exacerbates autoimmune cholangitis.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.3739958.3466056 ◽

2010 ◽

Author(s):

Tom Hemming Karlsen ◽

Espen Melum

Keyword(s):

Growth Factor ◽

Transforming Growth Factor Beta ◽

Interleukin 6 ◽

Transforming Growth Factor ◽

Dominant Negative ◽

Autoimmune Cholangitis ◽

Beta Receptor ◽

Dominant Negative Form ◽

Growth Factor Beta ◽

Negative Form

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Adoptive transfer of CD8+ T cells from transforming growth factor beta receptor type II (dominant negative form) induces autoimmune cholangitis in mice

Hepatology ◽

10.1002/hep.22226 ◽

2008 ◽

Vol 47 (6) ◽

pp. 1974-1982 ◽

Cited By ~ 76

Author(s):

Guo-Xiang Yang ◽

Zhe-Xiong Lian ◽

Ya-Hui Chuang ◽

Yuki Moritoki ◽

Ruth Y. Lan ◽

...

Keyword(s):

T Cells ◽

Cd8 T Cells ◽

Transforming Growth Factor Beta ◽

Transforming Growth Factor ◽

Dominant Negative ◽

Type Ii ◽

Autoimmune Cholangitis ◽

Dominant Negative Form ◽

Growth Factor Beta ◽

Negative Form

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Faculty Opinions recommendation of Deletion of interleukin-6 in mice with the dominant negative form of transforming growth factor beta receptor II improves colitis but exacerbates autoimmune cholangitis.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.3739958.4121054 ◽

2010 ◽

Author(s):

Jonathan A Dranoff

Keyword(s):

Growth Factor ◽

Transforming Growth Factor Beta ◽

Interleukin 6 ◽

Transforming Growth Factor ◽

Dominant Negative ◽

Autoimmune Cholangitis ◽

Beta Receptor ◽

Dominant Negative Form ◽

Growth Factor Beta ◽

Negative Form

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Growth inhibition by transforming growth factor beta (TGF-beta) type I is restored in TGF-beta-resistant hepatoma cells after expression of TGF-beta receptor type II cDNA.

Proceedings of the National Academy of Sciences ◽

10.1073/pnas.90.11.5359 ◽

1993 ◽

Vol 90 (11) ◽

pp. 5359-5363 ◽

Cited By ~ 118

Author(s):

M. Inagaki ◽

A. Moustakas ◽

H. Y. Lin ◽

H. F. Lodish ◽

B. I. Carr

Keyword(s):

Growth Factor ◽

Growth Inhibition ◽

Transforming Growth Factor Beta ◽

Transforming Growth Factor ◽

Hepatoma Cells ◽

Receptor Type ◽

Type I ◽

Type Ii ◽

Tgf Beta ◽

Growth Factor Beta

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Transforming Growth Factor Beta Receptor Type II Deletion Increases The Multiplicity And Growth Of K-RAS Induced Lung Cancers

10.1164/ajrccm-conference.2011.183.1_meetingabstracts.a4044 ◽

2011 ◽

Author(s):

Stephen Malkoski ◽

Timothy Cleaver ◽

Sarah Haeger ◽

Karen Rodriguez ◽

Jessyka Lighthall ◽

...

Keyword(s):

Growth Factor ◽

Transforming Growth Factor Beta ◽

Transforming Growth Factor ◽

Receptor Type ◽

Type Ii ◽

Lung Cancers ◽

Beta Receptor ◽

Growth Factor Beta

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Characteristics of transforming growth factor beta receptor type II (TGFβRII) membranous expression in prostate cancer (PCa)

European Urology Open Science ◽

10.1016/s2666-1683(21)03126-8 ◽

2021 ◽

Vol 33 ◽

pp. S266

Author(s):

M. Puchinskaya

Keyword(s):

Prostate Cancer ◽

Growth Factor ◽

Transforming Growth Factor Beta ◽

Transforming Growth Factor ◽

Receptor Type ◽

Type Ii ◽

Beta Receptor ◽

Growth Factor Beta

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Mutation analysis of transforming growth factor beta type I receptor, type II receptor, Smad2, Smad4, Smad6 and Smad7 in hepatocellular carcinoma

Gastroenterology ◽

10.1016/s0016-5085(00)81721-7 ◽

2000 ◽

Vol 118 (4) ◽

pp. A1456

Author(s):

Susumu Kawate ◽

Susumu Ohwada ◽

Hamada Kunihiro ◽

Toru Koyama ◽

Ichiro Sakamoto ◽

...

Keyword(s):

Hepatocellular Carcinoma ◽

Growth Factor ◽

Mutation Analysis ◽

Transforming Growth Factor Beta ◽

Transforming Growth Factor ◽

Receptor Type ◽

Type I ◽

Type Ii ◽

Growth Factor Beta

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Functional Analysis of Transforming Growth Factor-.BETA. type II Dominant Negative Receptor.

THE JOURNAL OF THE STOMATOLOGICAL SOCIETY JAPAN ◽

10.5357/koubyou.63.375 ◽

1996 ◽

Vol 63 (2) ◽

pp. 375-386 ◽

Cited By ~ 1

Author(s):

Masanori Takarada

Keyword(s):

Functional Analysis ◽

Growth Factor ◽

Transforming Growth Factor Beta ◽

Transforming Growth Factor ◽

Dominant Negative ◽

Type Ii ◽

Growth Factor Beta

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Reduced surface expression of transforming growth factor beta receptor type II in mitogen-activated T cells from Sezary patients.

Proceedings of the National Academy of Sciences ◽

10.1073/pnas.92.12.5501 ◽

1995 ◽

Vol 92 (12) ◽

pp. 5501-5505 ◽

Cited By ~ 43

Author(s):

R. J. Capocasale ◽

R. J. Lamb ◽

E. C. Vonderheid ◽

F. E. Fox ◽

A. H. Rook ◽

...

Keyword(s):

T Cells ◽

Growth Factor ◽

Transforming Growth Factor Beta ◽

Transforming Growth Factor ◽

Surface Expression ◽

Receptor Type ◽

Type Ii ◽

Activated T Cells ◽

Growth Factor Beta ◽

Reduced Surface

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