scholarly journals Early transcriptional programming links progression to hepatitis C virus-induced severe liver disease in transplant patients

Hepatology ◽  
2012 ◽  
Vol 56 (1) ◽  
pp. 17-27 ◽  
Author(s):  
Angela L. Rasmussen ◽  
Nicolas Tchitchek ◽  
Nathan J. Susnow ◽  
Alexei L. Krasnoselsky ◽  
Deborah L. Diamond ◽  
...  
Keyword(s):  
Hepatitis C Virus ◽  
Liver Disease ◽  
Hepatitis C ◽  
Severe Liver ◽  
Transplant Patients ◽  
Severe Liver Disease

scholarly journals Hepatitis C virus genotype 3 and the risk of severe liver disease in a large population of drug users in France

2010 ◽  
Vol 82 (10) ◽  
pp. 1647-1654 ◽  
Author(s):  
Christine Larsen ◽  
Vanina Bousquet ◽  
Elisabeth Delarocque-Astagneau ◽  
Corinne Pioche ◽  
Françoise Roudot-Thoraval
Keyword(s):  
Hepatitis C Virus ◽  
Liver Disease ◽  
Hepatitis C ◽  
Drug Users ◽  
Large Population ◽  
Genotype 3 ◽  
Severe Liver ◽  
Virus Genotype ◽  
Severe Liver Disease

Hepatitis C virus infection is the major cause of severe liver disease in India

1991 ◽  
Vol 26 (S3) ◽  
pp. 192-195 ◽  
Author(s):  
B. N. Tandon ◽  
M. Irshad ◽  
S. K. Acharya ◽  
Y. K. Joshi
Keyword(s):  
Hepatitis C Virus ◽  
Liver Disease ◽  
Hepatitis C ◽  
Virus Infection ◽  
Hepatitis C Virus Infection ◽  
Severe Liver ◽  
Severe Liver Disease

scholarly journals Apolipoprotein E-ϵ4 protects against severe liver disease caused by hepatitis C virus

Hepatology ◽  
2002 ◽  
Vol 36 (2) ◽  
pp. 456-463 ◽  
Author(s):  
Matthew A. Wozniak ◽  
Ruth F. Itzhaki ◽  
E. Brian Faragher ◽  
Martin W. James ◽  
Steven D. Ryder ◽  
...  
Keyword(s):  
Hepatitis C Virus ◽  
Liver Disease ◽  
Hepatitis C ◽  
Apolipoprotein E ◽  
Severe Liver ◽  
Severe Liver Disease

scholarly journals Severe liver disease related to chronic hepatitis C virus infection in treatment-naive patients: epidemiological characteristics and associated factors at first expert centre visit, France, 2000 to 2007 and 2010 to 2014

2017 ◽  
Vol 22 (30) ◽  
Author(s):  
Alice Sanna ◽  
Yann Le Strat ◽  
Françoise Roudot-Thoraval ◽  
Sylvie Deuffic Burban ◽  
Patrizia Carrieri ◽  
...  
Keyword(s):  
Chronic Hepatitis ◽  
Hepatitis C Virus ◽  
Liver Disease ◽  
Hepatitis C ◽  
Chronic Hepatitis C ◽  
Severe Liver ◽  
Factors Associated ◽  
Chronic Hepatitis C Virus ◽  
Severe Liver Disease ◽  
Epidemiological Characteristics

Given recent profound improvements in the effectiveness of antiviral treatment for chronic Hepatitis C virus (HCV) infection, we aimed to describe the characteristics of patients referred to hepatology expert centres in France from 2000 to 2007 and from 2010 to 2014, and to identify factors associated with severe liver disease at their first visit for evaluation. We analysed data from two sources covering all of France: the former hepatitis C surveillance network, which included patients between 2000 and 2007, and the ANRS CO22 HEPATHER multi-centre cohort, which included patients between 2012 and 2014. Severe liver disease (SLD) was defined as the presence of either cirrhosis (histological, biochemical or clinical) or hepatocellular carcinoma. Multivariable Poisson regression models were used to identify the factors associated with SLD in complete-case analysis and after multiple imputation. Overall, 16,851 patients were included in the analysis and SLD was diagnosed in 11.6%. SLD at first visit was significantly associated with known risk factors (male sex, history of excessive alcohol intake, HCV genotype 3), late referral to hepatologists after diagnosis and HCV diagnosis at an older age. Providing earlier specialised care and treatment may be an important target for public health action.

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