scholarly journals Visceral adiposity index is associated with histological findings and high viral load in patients with chronic hepatitis C due to genotype 1

Hepatology ◽  
2010 ◽  
Vol 52 (5) ◽  
pp. 1543-1552 ◽  
Author(s):  
Salvatore Petta ◽  
Marco Amato ◽  
Daniela Cabibi ◽  
Calogero Cammà ◽  
Vito Di Marco ◽  
...  
Keyword(s):  
Chronic Hepatitis ◽  
Viral Load ◽  
Hepatitis C ◽  
Chronic Hepatitis C ◽  
High Viral Load ◽  
Visceral Adiposity ◽  
Visceral Adiposity Index ◽  
Genotype 1 ◽  
Histological Findings ◽  
Adiposity Index

scholarly journals Association of Visceral Obesity with High Viral Load and Histological Findings in Elderly Patients with Genotype 1 Chronic Hepatitis C

2013 ◽  
Vol 52 (15) ◽  
pp. 1665-1673 ◽  
Author(s):  
Hironori Tsuzura ◽  
Takuya Genda ◽  
Shunsuke Sato ◽  
Katsuharu Hirano ◽  
Yoshio Kanemitsu ◽  
...  
Keyword(s):  
Chronic Hepatitis ◽  
Viral Load ◽  
Hepatitis C ◽  
Elderly Patients ◽  
Chronic Hepatitis C ◽  
Visceral Obesity ◽  
High Viral Load ◽  
Genotype 1 ◽  
Histological Findings

Randomized trial of low-dose peginterferon α-2b plus low and escalating doses of ribavirin in older patients with chronic hepatitis C with high viral load genotype 1

2015 ◽  
Vol 87 (12) ◽  
pp. 2082-2089
Author(s):  
Yoshiaki Iwasaki ◽  
Ryo-ichi Okamoto ◽  
Yasushi Ishii ◽  
Yasuyuki Araki ◽  
Noriaki Hashimoto ◽  
...  
Keyword(s):  
Chronic Hepatitis ◽  
Viral Load ◽  
Hepatitis C ◽  
Randomized Trial ◽  
Chronic Hepatitis C ◽  
Older Patients ◽  
Low Dose ◽  
High Viral Load ◽  
Genotype 1 ◽  
Peginterferon Α

Randomized trial of peginterferon alpha-2b plus low and escalating dose of ribavirin in patients with chronic hepatitis C with high viral load genotype 1

2015 ◽  
Vol 87 (4) ◽  
pp. 625-633 ◽  
Author(s):  
Yoshiaki Iwasaki ◽  
Yasuyuki Araki ◽  
Hideaki Taniguchi ◽  
Ryo-ichi Okamoto ◽  
Haruhiko Kobashi ◽  
...  
Keyword(s):  
Chronic Hepatitis ◽  
Viral Load ◽  
Hepatitis C ◽  
Randomized Trial ◽  
Chronic Hepatitis C ◽  
High Viral Load ◽  
Genotype 1

scholarly journals ASSOCIATION OF THE NUTRITIONAL PROFILE WITH HISTOLOGICAL FINDINGS OF PATIENTS WITH GENOTYPE 1 CHRONIC HEPATITIS C INFECTION

2015 ◽  
Vol 52 (4) ◽  
pp. 315-320
Author(s):  
Vanessa Aparecida de SANTIS E SILVA ◽  
Maria Lucia G FERRAZ ◽  
Roberto de CARVALHO-FILHO ◽  
Valeria Pereira LANZONI ◽  
Antonio Eduardo Benedito SILVA ◽  
...  
Keyword(s):  
Chronic Hepatitis ◽  
Quantitative Analysis ◽  
Hepatitis C ◽  
Waist Circumference ◽  
Food Intake ◽  
Hepatic Steatosis ◽  
Chronic Hepatitis C ◽  
Saturated Fat ◽  
Genotype 1 ◽  
Histological Findings

Background - Different factors are responsible for the progression of hepatic fibrosis in chronic infection with hepatitis C virus, but the role of nutritional factors in the progression of the disease is not clearly defined. This study aimed to evaluate the nutritional status and dietary profile among patients with chronic hepatitis C who were candidates for treatment and its association with histopathological features. Methods - A crossectional study was conducted on treatment-naïve patients with chronic hepatitis C genotype 1, between 2011 and 2013. The following assessments were performed before treatment: liver biopsy, anthropometric measurements and qualitative/quantitative analysis of food intake. Results - Seventy patients were studied. The majority of patients was classified as obese (34%) or overweight (20%) according to body mass index [BMI] and as at risk for cardiovascular diseases by waist circumference (79%). Unhealthy food intake was presented by 59% according to qualitative parameters and several patients showed an insufficient intake of calories (59%), excessive intake of protein (36%) and of saturated fat (63%), according to quantitative analysis. With respect to histology, 68% presented activity grade ≥2, 65% had steatosis and 25% exhibited fibrosis stage >2. Comparative analysis between anthropometric parameters and histological features showed that elevated waist circumference was the only variable associated to hepatic steatosis ( P =0.05). There was no association between qualitative and quantitative food intake parameters with histological findings. Conclusion - In this study, most of the patients with hepatitis C presented inadequate qualitative food intake and excessive consumption of saturated fat; in addition, excess of abdominal fat was associated to hepatic steatosis. Therefore, nutritional guidance should be implemented prior to treatment in patients with chronic hepatitis C, in order to avoid nutritional disorders and negative impact on the management of patients.

388 Race, insulin resistance, visceral adiposity and hepatic steatosis in genotype 1 patients with chronic hepatitis C

Hepatology ◽  
2003 ◽  
Vol 38 ◽  
pp. 347-347 ◽  
Author(s):  
H CONJEEVARAM ◽  
D KLEINER ◽  
N AFDHAL ◽  
R BROWN ◽  
M FRIED ◽  
...  
Keyword(s):  
Insulin Resistance ◽  
Chronic Hepatitis ◽  
Hepatitis C ◽  
Hepatic Steatosis ◽  
Chronic Hepatitis C ◽  
Visceral Adiposity ◽  
Genotype 1
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