Transforming growth factor-beta induces senescence in hepatocellular carcinoma cells and inhibits tumor growth

Serif Senturk; Mine Mumcuoglu; Ozge Gursoy-Yuzugullu; Burcu Cingoz; Kamil Can Akcali; Mehmet Ozturk

doi:10.1002/hep.23769

Transforming growth factor-beta induces senescence in hepatocellular carcinoma cells and inhibits tumor growth

Hepatology ◽

10.1002/hep.23769 ◽

2010 ◽

Vol 52 (3) ◽

pp. 966-974 ◽

Cited By ~ 125

Author(s):

Serif Senturk ◽

Mine Mumcuoglu ◽

Ozge Gursoy-Yuzugullu ◽

Burcu Cingoz ◽

Kamil Can Akcali ◽

...

Keyword(s):

Hepatocellular Carcinoma ◽

Growth Factor ◽

Tumor Growth ◽

Transforming Growth Factor Beta ◽

Transforming Growth Factor ◽

Carcinoma Cells ◽

Hepatocellular Carcinoma Cells ◽

Growth Factor Beta

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Faculty Opinions recommendation of Transforming growth factor-beta induces senescence in hepatocellular carcinoma cells and inhibits tumor growth.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.5261961.5217056 ◽

2010 ◽

Author(s):

Grace Guo ◽

Guodong Li

Keyword(s):

Hepatocellular Carcinoma ◽

Growth Factor ◽

Tumor Growth ◽

Transforming Growth Factor Beta ◽

Transforming Growth Factor ◽

Carcinoma Cells ◽

Hepatocellular Carcinoma Cells ◽

Growth Factor Beta

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Mucin1 mediates autocrine transforming growth factor beta signaling through activating the c-Jun N-terminal kinase/activator protein 1 pathway in human hepatocellular carcinoma cells

The International Journal of Biochemistry & Cell Biology ◽

10.1016/j.biocel.2014.11.012 ◽

2015 ◽

Vol 59 ◽

pp. 116-125 ◽

Cited By ~ 18

Author(s):

Qiongshu Li ◽

Guomu Liu ◽

Dan Shao ◽

Juan Wang ◽

Hongyan Yuan ◽

...

Keyword(s):

Hepatocellular Carcinoma ◽

Growth Factor ◽

Transforming Growth Factor Beta ◽

Transforming Growth Factor ◽

Carcinoma Cells ◽

Human Hepatocellular Carcinoma ◽

Activator Protein 1 ◽

Hepatocellular Carcinoma Cells ◽

Growth Factor Beta ◽

Human Hepatocellular Carcinoma Cells

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Blocking transforming growth factor-beta up-regulates E-cadherin and reduces migration and invasion of hepatocellular carcinoma cells

Hepatology ◽

10.1002/hep.22201 ◽

2008 ◽

Vol 47 (5) ◽

pp. 1557-1566 ◽

Cited By ~ 165

Author(s):

Emilia Fransvea ◽

Umberto Angelotti ◽

Salvatore Antonaci ◽

Gianluigi Giannelli

Keyword(s):

Hepatocellular Carcinoma ◽

Growth Factor ◽

Transforming Growth Factor Beta ◽

Transforming Growth Factor ◽

Carcinoma Cells ◽

Migration And Invasion ◽

Hepatocellular Carcinoma Cells ◽

Growth Factor Beta ◽

E Cadherin

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Downregulation of miR-23a and miR-24 in human hepatocellular carcinoma cells by Sorafenib via transforming growth factor-beta 1 in a SMAD dependent manner

Journal of Bioscience and Applied Research ◽

10.21608/jbaar.2019.147398 ◽

2019 ◽

Vol 5 (3) ◽

pp. 340-351

Author(s):

Eman Ayad ◽

Mohga Abdulla ◽

Hayat Sharada ◽

Abdel Hady Abdel Wahab ◽

Abeer Ashmawy

Keyword(s):

Hepatocellular Carcinoma ◽

Growth Factor ◽

Transforming Growth Factor Beta ◽

Transforming Growth Factor ◽

Carcinoma Cells ◽

Human Hepatocellular Carcinoma ◽

Dependent Manner ◽

Hepatocellular Carcinoma Cells ◽

Growth Factor Beta ◽

Human Hepatocellular Carcinoma Cells

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Upregulation of miR-23a∼27a∼24 decreases transforming growth factor-beta-induced tumor-suppressive activities in human hepatocellular carcinoma cells

International Journal of Cancer ◽

10.1002/ijc.23580 ◽

2008 ◽

Vol 123 (4) ◽

pp. 972-978 ◽

Cited By ~ 153

Author(s):

Shenglin Huang ◽

Xianghuo He ◽

Jie Ding ◽

Linhui Liang ◽

Yingjun Zhao ◽

...

Keyword(s):

Hepatocellular Carcinoma ◽

Growth Factor ◽

Transforming Growth Factor Beta ◽

Transforming Growth Factor ◽

Carcinoma Cells ◽

Human Hepatocellular Carcinoma ◽

Hepatocellular Carcinoma Cells ◽

Growth Factor Beta ◽

Human Hepatocellular Carcinoma Cells

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Expression of antisense fibronectin RNA in human colon carcinoma cells disrupts the regulation of carcinoembryonic antigen by transforming growth factor beta 1.

Journal of Biological Chemistry ◽

10.1016/s0021-9258(19)61971-x ◽

1994 ◽

Vol 269 (46) ◽

pp. 28764-28768

Author(s):

S Huang ◽

S Chakrabarty

Keyword(s):

Growth Factor ◽

Carcinoembryonic Antigen ◽

Colon Carcinoma ◽

Transforming Growth Factor Beta ◽

Transforming Growth Factor ◽

Human Colon ◽

Carcinoma Cells ◽

Colon Carcinoma Cells ◽

Human Colon Carcinoma ◽

Growth Factor Beta

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P0259 : Transendothelial migration depends on transforming growth factor beta in hepatocellular carcinoma progression

Journal of Hepatology ◽

10.1016/s0168-8278(15)30475-x ◽

2015 ◽

Vol 62 ◽

pp. S403

Author(s):

P. Koudelkova ◽

G. Weber ◽

S. Dooley ◽

V. Costina ◽

P. Findeisen ◽

...

Keyword(s):

Hepatocellular Carcinoma ◽

Growth Factor ◽

Transforming Growth Factor Beta ◽

Transforming Growth Factor ◽

Transendothelial Migration ◽

Growth Factor Beta

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Mutation analysis of transforming growth factor beta type II receptor, Smad2, and Smad4 in hepatocellular carcinoma.

International Journal of Oncology ◽

10.3892/ijo.14.1.127 ◽

1999 ◽

Cited By ~ 4

Author(s):

S Kawate ◽

S Takenoshita ◽

S Ohwada ◽

A Mogi ◽

T Fukusato ◽

...

Keyword(s):

Hepatocellular Carcinoma ◽

Growth Factor ◽

Mutation Analysis ◽

Transforming Growth Factor Beta ◽

Transforming Growth Factor ◽

Type Ii ◽

Growth Factor Beta

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Resistance of human squamous carcinoma cells to transforming growth factor beta 1 is a recessive trait.

Proceedings of the National Academy of Sciences ◽

10.1073/pnas.90.13.6280 ◽

1993 ◽

Vol 90 (13) ◽

pp. 6280-6284 ◽

Cited By ~ 14

Author(s):

M. Reiss ◽

T. Munoz-Antonia ◽

J. M. Cowan ◽

P. C. Wilkins ◽

Z. L. Zhou ◽

...

Keyword(s):

Growth Factor ◽

Transforming Growth Factor Beta ◽

Transforming Growth Factor ◽

Squamous Carcinoma ◽

Carcinoma Cells ◽

Recessive Trait ◽

Squamous Carcinoma Cells ◽

Growth Factor Beta

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Abstract C261: Pharmacokinetics (PK) and pharmacodynamics (PD) of the oral transforming growth factor-beta (TGF-β) receptor I kinase inhibitor LY2157299 monohydrate (LY) in hepatocellular carcinoma (HCC) compared to glioma patients.

10.1158/1535-7163.targ-13-c261 ◽

2013 ◽

Author(s):

Eric Raymond ◽

Sandrine Faivre ◽

Armondo Santoro ◽

Robin K. Kelley ◽

...

Keyword(s):

Hepatocellular Carcinoma ◽

Growth Factor ◽

Transforming Growth Factor Beta ◽

Transforming Growth Factor ◽

Kinase Inhibitor ◽

Growth Factor Beta ◽

Β Receptor

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