Treatment of stage I and II oral tongue cancer

Head & Neck ◽  
1993 ◽  
Vol 15 (4) ◽  
pp. 308-312 ◽  
Author(s):  
Daniel D. Lydiatt ◽  
K. Thomas Robbins ◽  
Robert M. Byers ◽  
Patricia F. Wolf
Keyword(s):  
Tongue Cancer ◽  
Stage I ◽  
Oral Tongue ◽  
Oral Tongue Cancer

Brachytherapy for stage I & II oral tongue cancer: An analysis of past cases focusing on control and complications

1993 ◽  
Vol 26 (1) ◽  
pp. 51-58 ◽  
Author(s):  
Hitoshi Shibuya ◽  
Masao Hoshina ◽  
Masamune Takeda ◽  
Satoru Matsumoto ◽  
Soj Suzuki ◽  
...  
Keyword(s):  
Tongue Cancer ◽  
Stage I ◽  
Oral Tongue ◽  
Oral Tongue Cancer

Is Long-Term Follow-Up Mandatory for Stage I Oral Tongue Cancer?

2018 ◽  
Vol 76 (12) ◽  
pp. 2676-2683 ◽  
Author(s):  
Robert A. Ord ◽  
Amal Isaiah ◽  
Donita Dyalram ◽  
Joshua E. Lubek
Keyword(s):  
Tongue Cancer ◽  
Stage I ◽  
Oral Tongue ◽  
Oral Tongue Cancer ◽  
Long Term Follow Up

Treatment results of stage I oral tongue cancer with definitive radiotherapy

Oral Oncology ◽  
2005 ◽  
Vol 41 (5) ◽  
pp. 520-525 ◽  
Author(s):  
Y ICHIMIYA ◽  
N FUWA ◽  
M KAMATA ◽  
T KODAIRA ◽  
K FURUTANI ◽  
...  
Keyword(s):  
Tongue Cancer ◽  
Stage I ◽  
Oral Tongue ◽  
Treatment Results ◽  
Definitive Radiotherapy ◽  
Oral Tongue Cancer

Regional recurrence in early stage I–II oral tongue cancer: a single institutional study and review of the literature

2017 ◽  
Vol 137 (7) ◽  
pp. 755-761 ◽  
Author(s):  
Alexander Kamali ◽  
Caroline Gahm ◽  
Björn Palmgren ◽  
Linda Marklund ◽  
Martin Halle ◽  
...  
Keyword(s):  
Tongue Cancer ◽  
Early Stage ◽  
Stage I ◽  
Regional Recurrence ◽  
Review Of The Literature ◽  
Oral Tongue ◽  
Oral Tongue Cancer

scholarly journals Prognostic significance of gene amplification of ACTN4 in stage I and II oral tongue cancer

2017 ◽  
Vol 46 (8) ◽  
pp. 968-976 ◽  
Author(s):  
T. Kakuya ◽  
T. Mori ◽  
S. Yoshimoto ◽  
Y. Watabe ◽  
N. Miura ◽  
...  
Keyword(s):  
Gene Amplification ◽  
Tongue Cancer ◽  
Prognostic Significance ◽  
Stage I ◽  
Oral Tongue ◽  
Oral Tongue Cancer

scholarly journals Improving Risk Stratification of Early Oral Tongue Cancer with TNM-Immune (TNM-I) Staging System

Cancers ◽  
2021 ◽  
Vol 13 (13) ◽  
pp. 3235
Author(s):  
Alhadi Almangush ◽  
Ibrahim O. Bello ◽  
Ilkka Heikkinen ◽  
Jaana Hagström ◽  
Caj Haglund ◽  
...  
Keyword(s):  
Overall Survival ◽  
Tongue Cancer ◽  
Early Stage ◽  
Disease Free Survival ◽  
Tumor Infiltrating Lymphocytes ◽  
Staging System ◽  
Oral Tongue ◽  
Oral Tongue Cancer ◽  
Important Player ◽  
Infiltrating Lymphocytes

Although patients with early-stage oral tongue squamous cell carcinoma (OTSCC) show better survival than those with advanced disease, there is still a number of early-stage cases who will suffer from recurrence, cancer-related mortality and worse overall survival. Incorporation of an immune descriptive factor in the staging system can aid in improving risk assessment of early OTSCC. A total of 290 cases of early-stage OTSCC re-classified according to the American Joint Committee on Cancer (AJCC 8) staging were included in this study. Scores of tumor-infiltrating lymphocytes (TILs) were divided as low or high and incorporated in TNM AJCC 8 to form our proposed TNM-Immune system. Using AJCC 8, there were no significant differences in survival between T1 and T2 tumors (p > 0.05). Our proposed TNM-Immune staging system allowed for significant discrimination in risk between tumors of T1N0M0-Immune vs. T2N0M0-Immune. The latter associated with a worse overall survival with hazard ratio (HR) of 2.87 (95% CI 1.92–4.28; p < 0.001); HR of 2.41 (95% CI 1.26–4.60; p = 0.008) for disease-specific survival; and HR of 1.97 (95% CI 1.13–3.43; p = 0.017) for disease-free survival. The TNM-Immune staging system showed a powerful ability to identify cases with worse survival. The immune response is an important player which can be assessed by evaluating TILs, and it can be implemented in the staging criteria of early OTSCC. TNM-Immune staging forms a step towards a more personalized classification of early OTSCC.

scholarly journals A systematic review and meta‐analysis of the prognostic role of age in oral tongue cancer

2021 ◽  
Author(s):  
Marta Tagliabue ◽  
Pietro Belloni ◽  
Rita De Berardinis ◽  
Sara Gandini ◽  
Francesco Chu ◽  
...  
Keyword(s):  
Systematic Review ◽  
Tongue Cancer ◽  
Meta Analysis ◽  
Oral Tongue ◽  
Prognostic Role ◽  
Oral Tongue Cancer
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