Tracheostomy scar management by repositioning platysma muscle and applying an acellular dermal substitute

Head & Neck ◽  
2019 ◽  
Author(s):  
Jeong Hyun Ha ◽  
Sang Wha Kim
Keyword(s):  
Dermal Substitute ◽  
Platysma Muscle ◽  
Scar Management ◽  
Acellular Dermal

Xenogeneic Acellular Dermal Matrix as a Dermal Substitute in Rats

1999 ◽  
Vol 20 (5) ◽  
pp. 382-390 ◽  
Author(s):  
Anil Srivastava ◽  
Lawrence J. Jennings ◽  
Marella Hanumadass ◽  
Stephen Sethi ◽  
Evangeline DeSagun ◽  
...  
Keyword(s):  
Acellular Dermal Matrix ◽  
Dermal Substitute ◽  
Dermal Matrix ◽  
Acellular Dermal

scholarly journals Use of Porcine Acellular Dermal Matrix as a Dermal Substitute in Rats

2001 ◽  
Vol 233 (3) ◽  
pp. 400-408 ◽  
Author(s):  
Anil Srivastava ◽  
Evangeline Z. DeSagun ◽  
Lawrence J. Jennings ◽  
Stephen Sethi ◽  
Anan Phuangsab ◽  
...  
Keyword(s):  
Acellular Dermal Matrix ◽  
Dermal Substitute ◽  
Dermal Matrix ◽  
Porcine Acellular Dermal Matrix ◽  
Acellular Dermal

scholarly journals Evaluation of lymphangiogenesis in acellular dermal matrix

2014 ◽  
Vol 47 (03) ◽  
pp. 318-324 ◽  
Author(s):  
Mario Cherubino ◽  
Igor Pellegatta ◽  
Federico Tamborini ◽  
Michele Cerati ◽  
Fausto Sessa ◽  
...  
Keyword(s):  
Wound Healing ◽  
Endothelial Cells ◽  
Cell Invasion ◽  
Acellular Dermal Matrix ◽  
Wound Contraction ◽  
Control Group ◽  
Dermal Substitute ◽  
Dermal Matrix ◽  
Microscopic Evaluation ◽  
Acellular Dermal

ABSTRACT Introduction: Much attention has been directed towards understanding the phenomena of angiogenesis and lymphangiogenesis in wound healing. Thanks to the manifold dermal substitute available nowadays, wound treatment has improved greatly. Many studies have been published about angiogenesis and cell invasion in INTEGRA®. On the other hand, the development of the lymphatic network in acellular dermal matrix (ADM) is a more obscure matter. In this article, we aim to characterize the different phases of host cell invasion in ADM. Special attention was given to lymphangiogenic aspects. Materials and Methods: Among 57 rats selected to analyse the role of ADM in lymphangiogenesis, we created four groups. We performed an excision procedure on both thighs of these rats: On the left one we did not perform any action except repairing the borders of the wound; while on the right one we used INTEGRA® implant. The excision biopsy was performed at four different times: First group after 7 days, second after 14 days, third after 21 days and fourth after 28 days. For our microscopic evaluation, we used the classical staining technique of haematoxylin and eosin and a semi-quantitative method in order to evaluate cellularity counts. To assess angiogenesis and lymphangiogenesis development we employed PROX-1 Ab and CD31/PECAM for immunohistochemical analysis. Results: We found remarkable wound contraction in defects that healed by secondary intention while minor wound contraction was observed in defects treated with ADM. At day 7, optical microscopy revealed a more plentiful cellularity in the granulation tissue compared with the dermal regeneration matrix. The immunohistochemical process highlighted vascular and lymphatic cells in both groups. After 14 days a high grade of fibrosis was noticeable in the non-treated group. At day 21, both lymphatic and vascular endothelial cells were better developed in the group with a dermal matrix application. At day 28, lymphatic endothelial cells had organized themselves, engineering the pseudocylindrical structure better disposed in the ADM group than in the control group, and the lymphatic cells were detectable inside the vessels’ lumen in this group. Conclusion: This study has made it possible to demonstrate the absolute importance of an ADM in proper wound healing and has shown better definition of both the qualitative and quantitative aspects of lymphangiogenesis compared to the second intention healing. A major grade of organization of the extracellular matrix and a minor grade of fibrosclerosis in ADM allowed a well-structured morphologic and functional development of the endothelial and lymphatic vascular structures. This study hopes to represent a clinical basis for a wider use of ADM in lesions where lymphatic complications are common.

scholarly journals Acellular dermal matrix used after large surgical ressection in ameloblastoma with buccal mucosa extension: a case report

2021 ◽  
Vol 10 (13) ◽  
pp. e564101321634
Author(s):  
Humberto Jácome-Santos ◽  
Fernanda Luiza Araújo de Lima Castro ◽  
Renata Gonçalves Resende ◽  
Renata de Carvalho Lacerda ◽  
Aline Fernanda Cruz ◽  
...  
Keyword(s):  
Oral Cavity ◽  
Buccal Mucosa ◽  
Inflammatory Diseases ◽  
Donor Site ◽  
Tumor Resection ◽  
Acellular Dermal Matrix ◽  
Donor Site Morbidity ◽  
Dermal Substitute ◽  
Dermal Matrix ◽  
Acellular Dermal

Neoplastic, traumatic, and inflammatory diseases of the oral cavity and oropharynx frequently result in significant defects after resection, also, they may present challenge reconstruction. Regional and distant flaps such as skin grafts (SGs) are routinely used to cover mucosal defects arising from large resections, to restore tissue volume and preserve function. However, there are some disadvantages, mainly related to the donor site morbidity, including pain, risk of infection, occasional hypertrophic scar, and additional contracture resulting from a relative lack of dermis. Therefore, acellular dermal membrane (ADM) seems to be an applicable option to avoid those issues, and it has been shown good results for covering tissue defects. Thus, this study reports the first experience of using the double-layer dermal substitute (DLDS) (NeveliaÒ made by Symatese, France) in oral cavity, to cover and repair a buccal defect, immediately after a large resection of ameloblastoma extending to buccal mucosa. After surgical intervention and actually in follow-up, the patient shows good aesthetic and functional status, 24 months postoperatively. Thus, this DLDS seems to be a good resource in primary buccal reconstruction after extensive tumor resection. However, more studies are needed to be performed.

Xenogenic Acellular Dermal Matrix as a Dermal Substitute in Rats

1998 ◽  
Vol 19 ◽  
pp. S172
Author(s):  
A K Srivastava ◽  
L J Jennings ◽  
M L Hanumadass ◽  
S Sethi ◽  
N Pavlis ◽  
...  
Keyword(s):  
Acellular Dermal Matrix ◽  
Dermal Substitute ◽  
Dermal Matrix ◽  
Acellular Dermal
Sign in / Sign up

Export Citation Format

Share Document