Concurrent chemoradiotherapy by simultaneously integrated boost volumetric‐modulated arc therapy for nasopharyngeal carcinoma‐toxicity/quality of life and survival

Head & Neck ◽  
2018 ◽  
Vol 41 (5) ◽  
pp. 1282-1289 ◽  
Author(s):  
Fu‐Min Fang ◽  
Tai‐Lin Huang ◽  
Yun‐Hsuan Lin ◽  
Chih‐Yen Chien ◽  
Hui‐Ching Chuang ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Nasopharyngeal Carcinoma ◽  
Concurrent Chemoradiotherapy ◽  
Volumetric Modulated Arc Therapy ◽  
Arc Therapy ◽  
Integrated Boost

scholarly journals Gross tumor volume determines toxicity and quality of life for patients with nasopharyngeal carcinoma treated by concurrent chemoradiotherapy with simultaneously integrated boost technique

2020 ◽  
Author(s):  
Tai-Lin Huang ◽  
Hui-Ching Chuang ◽  
Chun-Chieh Huang ◽  
Chih-Yen Chien ◽  
Shau-Hsuan Li ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Nasopharyngeal Carcinoma ◽  
Gross Tumor Volume ◽  
Concurrent Chemoradiotherapy ◽  
Tumor Volume ◽  
Organs At Risk ◽  
Integrated Boost ◽  
Eortc Qlq ◽  
The Impact

Abstract Background: To evaluate the impact of gross tumor volume (GTV) on toxicities and quality of life (QoL) for patients with nasopharyngeal carcinoma (NPC) treated by concurrent chemoradiotherapy with simultaneously integrated boost technique (chemo-SIB-IMRT). Methods: A total of 278 NPC patients with stage II-IVb treated by chemo-SIB-IMRT were enrolled. Toxicities were evaluated according to CTCAE version 4.03. QoL outcomes (n=219) were measured by using the EORTC QLQ-C30 and HN35 questionnaires at the time point of 12 months after chemo-SIB-IMRT. Results: A higher GTV was observed to be significantly associated with a higher mean or maximal dose in most organs at risk, together with more severe acute (mucositis, dermatitis, weight loss, and use of analgesic) and late toxicities (xerostomia, neck fibrosis, and radiation neuropathy). A linear regression model revealed that a higher GTV was significantly associated with a decline in role functioning and an increment in taste/smell, speech, social eating, opening mouth, dry mouth, and sticky saliva. Conclusion: GTV is the determining factor of some acute and late toxicities and QoL scales for NPC patients treated by chemo-SIB-IMRT.

Bowel and urinary quality of life after whole-pelvic versus prostate-only volumetric-modulated arc therapy for localized prostate cancer

2018 ◽  
Vol 8 (2) ◽  
pp. e49-e55
Author(s):  
Kentaro Ishii ◽  
Toshiko Yamanaga ◽  
Ryo Ogino ◽  
Yukinari Hosokawa ◽  
Shun Kishimoto ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Prostate Cancer ◽  
Volumetric Modulated Arc Therapy ◽  
Localized Prostate Cancer ◽  
Arc Therapy

scholarly journals Concurrent chemoradiotherapy degrades the quality of life of patients with stage II nasopharyngeal carcinoma as compared to radiotherapy

Oncotarget ◽  
2017 ◽  
Vol 8 (8) ◽  
pp. 14029-14038 ◽  
Author(s):  
Xin-Bin Pan ◽  
Shi-Ting Huang ◽  
Kai-Hua Chen ◽  
Yan-Ming Jiang ◽  
Jia-Lin Ma ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Nasopharyngeal Carcinoma ◽  
Concurrent Chemoradiotherapy ◽  
Stage Ii
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