Effects of octreotide therapy in progressive head and neck paragangliomas: Case series

Head & Neck ◽  
2013 ◽  
Vol 35 (12) ◽  
pp. E391-E396 ◽  
Author(s):  
Leonie T. van Hulsteijn ◽  
Nicolette van Duinen ◽  
Berit M. Verbist ◽  
Jeroen C. Jansen ◽  
Agatha A. van der Klaauw ◽  
...  
Diagnostics ◽  
2021 ◽  
Vol 12 (1) ◽  
pp. 28
Author(s):  
Anasuya Guha ◽  
Martin Chovanec

Head and neck paragangliomas (HNPGLs) are rare neuroendocrine tumors, comprising only 3% of all head and neck tumors. Early diagnosis forms an integral part of the management of these tumors. The two main aims of any treatment approach are long-term tumor control and minimal cranial nerve morbidity. The scope of this article is to present our case series of HNPGLs to stress most important clinical aspects of their presentation as well as critical issues of their complex management. Thirty patients with suspected HNPGLs were referred to our otorhinolaryngology clinic for surgical consultation between 2016–2020. We assessed the demographical pattern, clinicoradiological correlation, as well as type and outcome of treatment. A total of 42 non-secretory tumors were diagnosed—16.7% were incidental findings and 97% patients had benign tumors. Six patients had multiple tumors. Jugular paragangliomas were the most commonly treated tumors. Tumor control was achieved in nearly 96% of operated patients with minimal cranial nerve morbidity. Surgery is curative in most cases and should be considered as frontline treatment modality in experienced hands for younger patients, hereditary and secretory tumors. Cranial nerve dysfunction associated with tumor encasement is a negative prognostic factor for both surgery and radiotherapy. Multifocal tumors and metastasis are difficult to treat, even with early detection using genetic analysis. Detecting malignancy in HNPGLs is challenging due to the lack of histomorphological criteria; therefore, limited lymph node dissection should be considered, even in the absence of clinical and radiological signs of metastasis in carotid body, vagal, and jugular paragangliomas.


2017 ◽  
Vol 131 (7) ◽  
pp. 580-584 ◽  
Author(s):  
L Harrison ◽  
R Corbridge

AbstractBackground:Head and neck paragangliomas are rare. They are usually slow-growing, benign, non-catecholamine secreting tumours, traditionally treated with surgical excision. Complications of surgical excision include lower cranial nerve palsies, stroke and death.Method:A retrospective case note analysis was conducted of patients with head and neck paragangliomas treated with a watch-and-scan policy from March 2003 to September 2015, and the relevant literature was reviewed.Results:Fifteen head and neck paragangliomas were identified. None of the patients developed a new lower cranial nerve palsy or progression of their presenting hearing loss during the follow-up period. Five patients displayed an increase in maximum linear dimension of 4 mm over an average of 57.4 months. A review of the literature showed that a watch-and-surveillance scan policy is evolving as a treatment option for head and neck paragangliomas without malignant risk factors.Conclusion:Readily available surveillance scanning in head and neck paragangliomas enables the monitoring of head and neck paragangliomas, which may allow for avoidance of major surgery.


2016 ◽  
Vol 77 (S 02) ◽  
Author(s):  
Marcello Marchetti ◽  
Valentina Pinzi ◽  
Francesco Prada ◽  
Elena De Martin ◽  
Valeria Cuccarini ◽  
...  

Skull Base ◽  
2007 ◽  
Vol 17 (S 1) ◽  
Author(s):  
Franco Trabalzini ◽  
Francesca Schiavi ◽  
Giuseppe Opocher ◽  
Pietro Amistà

Skull Base ◽  
2009 ◽  
Vol 19 (01) ◽  
Author(s):  
Carsten Boedeker ◽  
Zoran Erlic ◽  
Roland Laszig ◽  
Wolfgang Maier ◽  
Jörg Schipper ◽  
...  

2018 ◽  
Author(s):  
Jose-Maria Recio-Cordova ◽  
Cecilia Higueruela ◽  
Rocio Caceres ◽  
Maria Garcia-Duque ◽  
Rogelio Gonzalez-Sarmiento ◽  
...  

Author(s):  
Prasetyanugraheni Kreshanti ◽  
Nandya Titania Putri ◽  
Valencia Jane Martin ◽  
Chaula Luthfia Sukasah

2021 ◽  
Vol 42 (4) ◽  
pp. 102992
Author(s):  
Margaret B. Mitchell ◽  
Kyle Kimura ◽  
Nikita Chapurin ◽  
Mario Saab-Chaloub ◽  
Mitra Mehrad ◽  
...  

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