Intratumoral vessel density as prognostic factors in head and neck squamous cell carcinoma: A meta-analysis of literature

Head & Neck ◽  
2013 ◽  
Vol 36 (4) ◽  
pp. 596-602 ◽  
Author(s):  
Min Yu ◽  
Lei Liu ◽  
Chunshui Liang ◽  
Ping Li ◽  
Xuelei Ma ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Prognostic Factors ◽  
Cell Carcinoma ◽  
Head And Neck ◽  
Squamous Cell ◽  
Meta Analysis ◽  
Vessel Density ◽  
Neck Squamous Cell Carcinoma ◽  
Intratumoral Vessel

Activity of weekly paclitaxel−cetuximab chemotherapy in unselected patients with recurrent/metastatic head and neck squamous cell carcinoma: prognostic factors

2017 ◽  
Vol 19 (6) ◽  
pp. 769-776 ◽  
Author(s):  
I. Pajares Bernad ◽  
J. Martínez Trufero ◽  
L. Calera Urquizu ◽  
R. A. Pazo Cid ◽  
A. Cebollero de Miguel ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Prognostic Factors ◽  
Cell Carcinoma ◽  
Head And Neck ◽  
Squamous Cell ◽  
Neck Squamous Cell Carcinoma ◽  
Weekly Paclitaxel

Prognostic factors of unknown primary head and neck squamous cell carcinoma

2008 ◽  
Vol 139 (3) ◽  
pp. 429-435 ◽  
Author(s):  
Chun-Chi Huang ◽  
Fen-Yu Tseng ◽  
Te-Huei Yeh ◽  
Yu-Hsuan Wen ◽  
Chuang-Jen Hsu ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Prognostic Factors ◽  
Cell Carcinoma ◽  
Head And Neck ◽  
Squamous Cell ◽  
Neck Squamous Cell Carcinoma ◽  
Unknown Primary

scholarly journals The Prognostic Value of Toll-Like Receptors in Head and Neck Squamous Cell Carcinoma: A Systematic Review and Meta-Analysis

2020 ◽  
Vol 21 (19) ◽  
pp. 7255
Author(s):  
Shrabon Hasnat ◽  
Roosa Hujanen ◽  
Bright I. Nwaru ◽  
Tuula Salo ◽  
Abdelhakim Salem
Keyword(s):  
Systematic Review ◽  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Head And Neck ◽  
Squamous Cell ◽  
Prognostic Value ◽  
Meta Analysis ◽  
Small Sample ◽  
Neck Squamous Cell Carcinoma ◽  
Toll Like Receptors

Head and neck squamous cell carcinoma (HNSCC) is a group of tumours which exhibit low 5 year survival rates. Thus, there is an urgent need to identify biomarkers that may improve the clinical utility of patients with HNSCC. Emerging studies support a role of toll-like receptors (TLRs) in carcinogenesis. Therefore, this systematic review and meta-analysis was performed to assess the prognostic value of TLR immunoexpression in HNSCC patients. We compiled the results of thirteen studies comprising 1825 patients, of which six studies were deemed qualified for quantitative synthesis. The higher immunoexpression of TLR-1 to 5 and 9 was associated with a worsening of the clinical parameters of patients with HNSCC. Furthermore, induced levels of TLR-3, 4, 5, 7 and 9 were found to predict the patients’ survival time. The meta-analysis revealed that TLR-7 overexpression is associated with a decreased mortality risk in HNSCC patients (HR 0.51; 95%CI 0.13–0.89; I2 34.6%), while a higher expression of TLR-5 predicted shorter, but non-significant, survival outcome. In conclusion, this review suggests that TLRs may represent some prognostic value for patients with HNSCC. However, due to small sample sizes and other inherent methodological limitations, more well designed studies across different populations are still needed before TLRs can be recommended as a reliable clinical risk-stratification tool.

scholarly journals Locoregionally recurrent head and neck squamous cell carcinoma: incidence, survival, prognostic factors, and treatment outcomes

Oncotarget ◽  
2017 ◽  
Vol 8 (33) ◽  
pp. 55600-55612 ◽  
Author(s):  
Jer-Hwa Chang ◽  
Chia-Che Wu ◽  
Kevin Sheng-Po Yuan ◽  
Alexander T.H. Wu ◽  
Szu-Yuan Wu
Keyword(s):  
Squamous Cell Carcinoma ◽  
Prognostic Factors ◽  
Cell Carcinoma ◽  
Head And Neck ◽  
Treatment Outcomes ◽  
Squamous Cell ◽  
Neck Squamous Cell Carcinoma ◽  
Recurrent Head
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