Second primary lung cancer after head and neck squamous cell cancer: Population-based study of risk factors

Head & Neck ◽  
2012 ◽  
Vol 34 (12) ◽  
pp. 1782-1788 ◽  
Author(s):  
Michael T. Milano ◽  
Carl R. Peterson ◽  
Hong Zhang ◽  
Deepinder P. Singh ◽  
Yuhchyau Chen
Keyword(s):  
Risk Factors ◽  
Lung Cancer ◽  
Squamous Cell Cancer ◽  
Cell Cancer ◽  
Primary Lung Cancer ◽  
Population Based ◽  
Second Primary ◽  
Population Based Study ◽  
Second Primary Lung Cancer ◽  
Neck Squamous Cell Cancer

scholarly journals Clinical characteristics and risk of second primary lung cancer after cervical cancer: A population-based study

PLoS ONE ◽  
2020 ◽  
Vol 15 (8) ◽  
pp. e0231807
Author(s):  
Chengyuan Qian ◽  
Hong Liu ◽  
Yan Feng ◽  
Shenglan Meng ◽  
Dong Wang ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Cervical Cancer ◽  
Clinical Characteristics ◽  
Primary Lung Cancer ◽  
Population Based ◽  
Second Primary ◽  
Population Based Study ◽  
Second Primary Lung Cancer

scholarly journals Clinical Characteristics and Risk of Second Primary Lung Cancer After Cervix Cancer: A Population-Based Study

2020 ◽  
Author(s):  
Chengyuan Qian ◽  
Hong Liu ◽  
Yan Feng ◽  
Shenglan Meng ◽  
Dong Wang ◽  
...  
Keyword(s):  
Risk Factors ◽  
Lung Cancer ◽  
Cervical Cancer ◽  
Clinical Characteristics ◽  
Primary Lung Cancer ◽  
Population Based ◽  
Cervix Cancer ◽  
Second Primary ◽  
Second Primary Lung Cancer ◽  
History Of

AbstractBackgroundLung cancer as a second primary malignancy is increasingly common, but the clinical characteristics of second primary non-small cell lung cancer after cervix cancer (CC-NSCLC) in comparison with first primary non-small cell lung cancer (NSCLC1) is unknown.MethodsThe Surveillance, Epidemiology and EndResults (SEER) cancer registry between 1998 and 2010 was used to conduct a large population-based cohort analysis. Demographic and clinical characteristics as well as prognostic data were systematically analyzed. We further compared overall survival (OS) in the two cohorts. Risk factors of secondary primary lung cancer in cervical cancer patients were also analyzed.Results557 (3.52%) had developed second primary lung cancer after cervix cancer and 451 were eligible for inclusion in the final analyses. In comparison to NSCLC1, patients with CC-NSCLC had a higher rate of squamous cell carcinoma (SCC) (36.59% vs. 19.07%, p<0.01). Median OS was longer for CC-NSCLC than for NSCLC1 before propensity score matching (PSM) (16 vs. 13months) but there was no significant difference after PSM. High-risk factors in cervical cancer to developing CC-NSCLC include: 50-79years old, black race (OR 1.417; 95%CI 1.095-1.834; p<0.05)and history of radiotherapy (OR 1.392; 95%CI 1.053-1.841; p<0.05).Conclusion50-79years old, black race and history of radiotherapy were independent risk factors of second primary lung cancer in cervical cancer patient. CC-NSCLC patients had distinctive clinical characteristics and a better prognosis compared with NSCLC1 patients.

Second primary lung cancer following laryngeal cancer: retrospective study of incidence and multivariate analysis of risk factors in 209 patients

2019 ◽  
Vol 133 (11) ◽  
pp. 974-979 ◽  
Author(s):  
M Adams ◽  
G Gray ◽  
A Kelly ◽  
F Toner ◽  
R Ullah
Keyword(s):  
Risk Factors ◽  
Lung Cancer ◽  
Laryngeal Cancer ◽  
Primary Lung Cancer ◽  
Case Series ◽  
Hazard Ratio ◽  
Second Primary ◽  
Second Primary Lung Cancer ◽  
Increased Risk ◽  
Computed Tomography Scanning

AbstractObjectiveTo analyse the incidence of second primary lung cancer following treatment for laryngeal cancer and to identify risk factors for its development.MethodRetrospective case series.ResultsThe five-year actuarial incidence of second primary lung cancer was 8 per cent (1.6 per cent per year). This was associated with a very poor median survival of seven months following diagnosis. Supraglottic tumours were associated with an increased risk of second primary lung cancer compared to glottic tumours in both univariate (hazard ratio = 4.32, p = 0.005) and multivariate analyses (hazard ratio = 4.14, p = 0.03).ConclusionSecond primary lung cancer occurs at a rate of 1.6 per cent per year following a diagnosis of laryngeal cancer, and this is associated in a statistically significant manner with supraglottic primary tumour. The recent National Lung Cancer Screening Trial suggests a survival advantage of 20 per cent at five years with annual screening using low-dose computed tomography scanning of the chest in a comparable cohort to ours. These findings have the potential to inform post-treatment surveillance protocols in the future.

scholarly journals Risk Factors Associated with a Second Primary Lung Cancer in Patients with an Initial Primary Lung Cancer

2021 ◽  
Author(s):  
Amanda Fisher ◽  
Seongho Kim ◽  
Dina Farhat ◽  
Kimberly Belzer ◽  
MaryAnn Milczuk ◽  
...  
Keyword(s):  
Risk Factors ◽  
Lung Cancer ◽  
Primary Lung Cancer ◽  
Second Primary ◽  
Factors Associated ◽  
Second Primary Lung Cancer
Sign in / Sign up

Export Citation Format

Share Document