scholarly journals Control of the pharyngeal musculature during wakefulness and sleep: Implications in normal controls and sleep apnea

Head & Neck ◽  
2011 ◽  
Vol 33 (S1) ◽  
pp. S37-S45 ◽  
Author(s):  
Bradley A. Edwards ◽  
David P. White
Keyword(s):  
Sleep Apnea ◽  
Pharyngeal Musculature ◽  
Normal Controls

scholarly journals Cone-beam CT analysis of patients with obstructive sleep apnea compared to normal controls

2016 ◽  
Vol 46 (1) ◽  
pp. 9 ◽  
Author(s):  
Allison Buchanan ◽  
Ruben Cohen ◽  
Stephen Looney ◽  
Sajitha Kalathingal ◽  
Scott De Rossi
Keyword(s):  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
Cone Beam Ct ◽  
Cone Beam ◽  
Obstructive Sleep ◽  
Ct Analysis ◽  
Normal Controls

Digital fluoroscopy before and after laser uvulopalatopharyngoplasty in obstructive sleep apnea

1997 ◽  
Vol 38 (2) ◽  
pp. 214-221 ◽  
Author(s):  
Y. Tsushima ◽  
J. Antila ◽  
E. Laurikainen ◽  
E. Svedström ◽  
O. Polo ◽  
...  
Keyword(s):  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
Upper Airway ◽  
Poor Responders ◽  
Dynamic Changes ◽  
Digital Fluoroscopy ◽  
Obstructive Sleep ◽  
Before And After ◽  
Cephalometric Measurements ◽  
Normal Controls

Purpose: to study the changes in pharyngeal behavior after laser uvulopalatopharyngoplasty (LUPPP). Material and Methods: the dynamic changes in the upper airway size were evaluated with digital fluoroscopy in 24 patients with obstructive sleep apnea (OSA) before and after LUPPP and in 16 normal controls, while they were awake and breathing normally. Cephalometric measurements were also made. the patients were classified into the categories of good and poor responders by means of a static-charge-sensitive bed. Results: Following LUPPP, collapsibility at the velopharyngeal level was within the normal range in 15 of 17 good responders, but only in 2 of 7 poor responders (p=0.0086). the minimum airway size at the same level showed a similar trend. in 3 of 7 poor responders the hyoid bone was positioned more caudally than in the good responders (p=0.017). Conclusion: Digital fluoroscopy provides information on the change in upper airway behavior after LUPPP.

scholarly journals Alternations of Circadian Clock Genes Expression and Oscillation in Obstructive Sleep Apnea

2019 ◽  
Vol 8 (10) ◽  
pp. 1634 ◽  
Author(s):  
Yang ◽  
Lin ◽  
Lin ◽  
Lin ◽  
Chen ◽  
...  
Keyword(s):  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
Circadian Clock ◽  
Clock Genes ◽  
Expression Patterns ◽  
Binary Logistic Regression Analysis ◽  
Chain Reactions ◽  
Obstructive Sleep ◽  
Circadian Clock Genes ◽  
Normal Controls

Circadian misalignment plays an important role in disease processes and can affect disease severity, treatment outcomes, and even survivorship. In this study, we aim to investigate whether expression and daily oscillation patterns of core circadian clock genes were disturbed in patients with obstructive sleep apnea/hypopnea (OSA) syndrome. We performed real-time quantitative reverse transcriptase-polymerase chain reactions to examine the expression of the nine core circadian clock genes in leukocytes of peripheral blood collected at 12 AM, 6 AM, 12 PM, and 6 PM from 133 patients with OSA and 11 normal controls. Daily expression patterns of the nine circadian clock genes were observed in normal controls, but three of these genes (BMAL1, CLOCK, CRY2) were disrupted in patients with OSA. The expressions of eight circadian clock genes (except PER1) at midnight were significantly downregulated in patients with severe OSA. Binary logistic regression analysis selected CRY1 and PER3 as independent factors for severe OSA and showed that the combined expressions of CRY1 and PER3 enhanced the capability of predicting severe OSA (Odds ratio, 5.800; 95% CI, 1.978 to 17.004; p = 0.001). Our results show that combined expressions of CRY1 and PER3 at midnight could be a potential predictor for severe OSA.

Comparison of lingual tonsil size as depicted on MR imaging between children with obstructive sleep apnea despite previous tonsillectomy and adenoidectomy and normal controls

2006 ◽  
Vol 36 (6) ◽  
pp. 518-523 ◽  
Author(s):  
Bradley L. Fricke ◽  
Lane F. Donnelly ◽  
Sally R. Shott ◽  
Maninder Kalra ◽  
Stacy A. Poe ◽  
...  
Keyword(s):  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
Mr Imaging ◽  
Lingual Tonsil ◽  
Obstructive Sleep ◽  
Normal Controls

Comparison of Psychiatric Symptoms in Patients With Obstructive Sleep Apnea, Simple Snoring, and Normal Controls

2018 ◽  
Vol 80 (2) ◽  
pp. 193-199 ◽  
Author(s):  
Jae Myeong Kang ◽  
Seong-Jin Cho ◽  
Yu Jin Lee ◽  
Ji-Eun Kim ◽  
Seung-Heon Shin ◽  
...  
Keyword(s):  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
Psychiatric Symptoms ◽  
Obstructive Sleep ◽  
Normal Controls ◽  
Simple Snoring
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