scholarly journals Supracricoid partial laryngectomy as salvage surgery for radiation therapy failure

Head & Neck ◽  
2008 ◽  
Vol 30 (8) ◽  
pp. 1064-1071 ◽  
Author(s):  
Alberto Deganello ◽  
Oreste Gallo ◽  
Jano Maria De Cesare ◽  
Maria Benedetta Ninu ◽  
Gianni Gitti ◽  
...  
Keyword(s):  
Radiation Therapy ◽  
Salvage Surgery ◽  
Partial Laryngectomy ◽  
Therapy Failure ◽  
Supracricoid Partial Laryngectomy

scholarly journals Supracricoid partial laryngectomy with cricohyoidoepiglottopexy in patients with radiation therapy failure

2009 ◽  
Vol 7 (1) ◽  
Author(s):  
Kuauhyama Luna-Ortiz ◽  
Philippe Pasche ◽  
Mario Tamez-Velarde ◽  
Veronica Villavicencio-Valencia
Keyword(s):  
Radiation Therapy ◽  
Partial Laryngectomy ◽  
Therapy Failure ◽  
Supracricoid Partial Laryngectomy

Supracricoid partial laryngectomy as salvage surgery after radiation failure

Head & Neck ◽  
2002 ◽  
Vol 24 (8) ◽  
pp. 759-765 ◽  
Author(s):  
Giuseppe Spriano ◽  
Raul Pellini ◽  
Guglielmo Romano ◽  
Luca Muscatello ◽  
Raffaele Roselli
Keyword(s):  
Salvage Surgery ◽  
Partial Laryngectomy ◽  
Supracricoid Partial Laryngectomy

Supracricoid Partial Laryngectomy After Failed Laryngeal Radiation Therapy

1996 ◽  
Vol 106 (4) ◽  
pp. 495-498 ◽  
Author(s):  
Ollivier Laccourreye ◽  
Gregory Weinstein ◽  
Philippe Naudo ◽  
Régis Cauchois ◽  
Henri Laccourreye ◽  
...  
Keyword(s):  
Radiation Therapy ◽  
Partial Laryngectomy ◽  
Supracricoid Partial Laryngectomy

Mucoepidermoid Carcinomas of the Larynx

2022 ◽  
pp. 000348942110694
Author(s):  
Holden W. Richards ◽  
Caitlin Bertelsen ◽  
Bronwyn Hamilton ◽  
David Sauer ◽  
Joshua Schindler
Keyword(s):  
Radiation Therapy ◽  
Radical Neck Dissection ◽  
Case Series ◽  
Tumor Grade ◽  
Tertiary Hospital ◽  
Additional Treatment ◽  
Partial Laryngectomy ◽  
High Grade ◽  
Intermediate Grade ◽  
Postoperative Radiation Therapy

Objectives: Discussions regarding the specific management and outcomes for laryngeal MEC are limited to very small, single-institution case series. To look further into the diagnosis and management of these uncommon non-squamous cell carcinomas of the larynx, we present 3 recent cases of laryngeal MEC treated at our institution. Methods: Patients at a tertiary hospital treated for MEC between October 2019 and December 2020 were retrospectively identified. Chart review, imaging analysis, and histologic slide creation were completed for all patients. Results: We identified and treated 2 patients with high-grade supraglottic and 1 patient with intermediate-grade glottic MEC. These patients presented to our clinic with a primary complaint of either gradual, worsening dysphonia, dysphagia, or both. All patients underwent laryngovideostroboscopy as well as panendoscopy with directed submucosal biopsy, which was consistent with MEC. MRI was performed in 2 of the cases further elucidating the extent of submucosal spread. PET-CT was performed in all 3 cases, and none demonstrated evidence of regional or distal metastases. Surgically, high-grade MEC lesions were treated with a total laryngectomy. The intermediate MEC lesion was managed with a supracricoid partial laryngectomy (SCPL). Surgical margins were free of tumor in all cases with no nodal metastases by modified radical neck dissection. Radiation therapy was offered to both high-grade MEC patients and declined by one. Radiation was not recommended to the patient with intermediate-grade MEC as we believed that the risk of additional treatment outweighed the benefit. Conclusion: We believe that MEC of the larynx should be considered in patients with atypical submucosal laryngeal masses. Laryngovideostroboscopy, MRI, and PET imaging may be valuable in determining the extent of the lesions and planning appropriate surgery. Postoperative radiation therapy should be considered a per tumor grade in other more studied sites, as there is no data on efficacy in laryngeal MEC.

Prognostic Factors in Early Glottic Carcinoma Implications for Treatment

2005 ◽  
Vol 91 (2) ◽  
pp. 182-187 ◽  
Author(s):  
Demiral Ayse Nur ◽  
Cetinayak Oguz ◽  
Erdag Taner Kemal ◽  
Eyiler Ferhat ◽  
Sarıoglu Sülen ◽  
...  
Keyword(s):  
Prognostic Factors ◽  
Treatment Time ◽  
Salvage Surgery ◽  
Anterior Commissure ◽  
The Other ◽  
Second Primary ◽  
Partial Laryngectomy ◽  
Glottic Carcinoma ◽  
T Classification ◽  
Early Glottic Carcinoma

Aim In this study we aimed to determine the prognostic factors affecting local control (LC) in limited glottic carcinoma treated with definitive radiotherapy (RT). Material and methods Between June 1991 and December 2001, 114 patients with early squamous-cell carcinoma of the glottis were treated with definitive RT at our institution. Only four (3.5%) patients were women. The median age was 60 (27-79). Fifteen percent, 72% and 13% of the patients had Tis, T1 and T2 tumors, respectively. Forty-three (37.7%) patients had anterior commissure invasion. Prior to RT 35 (31%) patients had undergone vocal cord stripping and two (2%) cordectomy. A median dose of 66 Gy (50-70.2) was given over a median period of 46 days (20-60). Univariate and multivariate analyses were performed for LC. The prognostic parameters analyzed for LC were T classification, anterior commissure involvement, total RT dose, and overall treatment time. Results Five-year local and regional control rates were 84.2% and 97.7%. RTOG grade 3-4 late side effects were observed only in one (0.9%) patient. In 15 patients with local failure, salvage treatment consisted of partial laryngectomy in eight patients and total laryngectomy in five. One of the remaining two patients was medically inoperable, and the other refused salvage surgery. In one of the three patients with regional failure, salvage surgery was applied and the other two were given palliative chemotherapy because of unresectable disease. Following salvage treatments, the ultimate five-year LC rate was 96.9% and the five-year larynx preservation rate was 91.1%. Second primary cancer was diagnosed in 17 (14.9%) patients. Only one patient developed distant metastases and two patients died of laryngeal cancer. While T2 disease and anterior commissure involvement were found to be unfavorable prognostic factors significantly influencing LC in univariate analyses, only T2 disease remained independent in multivariate analysis. Conclusion In patients with early glottic carcinoma, T classification proved to be the only independent prognostic factor affecting LC after primary radiotherapy according to the results of this study.

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