Gamma radiation-induced apoptosis, G2 delay, and the risk of salivary and thyroid carcinomas?a preliminary report

Head & Neck ◽  
2004 ◽  
Vol 26 (7) ◽  
pp. 612-618 ◽  
Author(s):  
Rong Zheng ◽  
Kristina R. Dahlstrom ◽  
Qingyi Wei ◽  
Erich M. Sturgis
Keyword(s):  
Gamma Radiation ◽  
Preliminary Report ◽  
Thyroid Carcinomas ◽  
Radiation Induced ◽  
Induced Apoptosis ◽  
G2 Delay

Geraniin down regulates gamma radiation-induced apoptosis by suppressing DNA damage

2013 ◽  
Vol 57 ◽  
pp. 147-153 ◽  
Author(s):  
So Jin Bing ◽  
Danbee Ha ◽  
Min Ju Kim ◽  
Eunjin Park ◽  
Ginnae Ahn ◽  
...  
Keyword(s):  
Dna Damage ◽  
Gamma Radiation ◽  
Radiation Induced ◽  
Induced Apoptosis

Gene expression profiling in MOLT-4 cells during gamma-radiation-induced apoptosis

Tumor Biology ◽  
2012 ◽  
Vol 33 (3) ◽  
pp. 689-700 ◽  
Author(s):  
Theres Lindgren ◽  
Torgny Stigbrand ◽  
Katrine Riklund ◽  
Lennart Johansson ◽  
David Eriksson
Keyword(s):  
Gene Expression ◽  
Gamma Radiation ◽  
Gene Expression Profiling ◽  
Expression Profiling ◽  
Radiation Induced ◽  
Induced Apoptosis

scholarly journals Mitigation of whole-body gamma radiation–induced damages by Clerodendron infortunatum in mammalian organisms

2016 ◽  
Vol 58 (3) ◽  
pp. 281-291 ◽  
Author(s):  
Tiju Chacko ◽  
Aditya Menon ◽  
Teeju Majeed ◽  
Sivaprabha V. Nair ◽  
Nithu Sara John ◽  
...  
Keyword(s):  
Gamma Radiation ◽  
Whole Body ◽  
Radiation Toxicity ◽  
Alcoholic Extract ◽  
Repair Gene ◽  
Total Blood ◽  
Dna Repair Gene ◽  
Radiation Induced ◽  
Induced Apoptosis ◽  
Cellular Dna

Abstract Several phytoceuticals and extracts of medicinal plants are reported to mitigate deleterious effects of ionizing radiation. The potential of hydro-alcoholic extract of Clerodendron infortunatum (CIE) for providing protection to mice exposed to gamma radiation was investigated. Oral administration of CIE bestowed a survival advantage to mice exposed to lethal doses of gamma radiation. Radiation-induced depletion of the total blood count and bone marrow cellularity were prevented by treatment with CIE. Damage to the cellular DNA (as was evident from the comet assay and the micronucleus index) was also found to be decreased upon CIE administration. Radiation-induced damages to intestinal crypt cells was also reduced by CIE. Studies on gene expression in intestinal cells revealed that there was a marked increase in the Bax/Bcl-2 ratio in mice exposed to whole-body 4 Gy gamma radiation, and that administration of CIE resulted in significant lowering of this ratio, suggestive of reduction of radiation-induced apoptosis. Also, in the intestinal tissue of irradiated animals, following CIE treatment, levels of expression of the DNA repair gene Atm were found to be elevated, and there was reduction in the expression of the inflammatory Cox-2 gene. Thus, our results suggest a beneficial use of Clerodendron infortunatum for mitigating radiation toxicity.

Gamma Radiation Induced Effects on Cefuroxime and Cefotaxime. Investigation on Degradation and Syn-Anti Isomerization

1994 ◽  
Vol 20 (16) ◽  
pp. 2493-2508 ◽  
Author(s):  
E. Ciranni Signoretti ◽  
L. Valvo ◽  
P. Fattibene ◽  
S. Onori ◽  
M. Pantaloni
Keyword(s):  
Gamma Radiation ◽  
Radiation Induced
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