Glomus jugulare tumor: Tumor control and complications after stereotactic radiosurgery

Head & Neck ◽  
2002 ◽  
Vol 24 (4) ◽  
pp. 332-339 ◽  
Author(s):  
Robert L. Foote ◽  
Bruce E. Pollock ◽  
Deborah A. Gorman ◽  
Paula J. Schomberg ◽  
Scott L. Stafford ◽  
...  
2019 ◽  
Author(s):  
Neil Patel ◽  
Matthew Carlson ◽  
Bruce Pollock ◽  
Colin Driscoll ◽  
Brian Neff ◽  
...  

2009 ◽  
Vol 27 (6) ◽  
pp. E5 ◽  
Author(s):  
Zachary D. Guss ◽  
Sachin Batra ◽  
Gordon Li ◽  
Steven D. Chang ◽  
Andrew T. Parsa ◽  
...  

In this article the authors review the literature for recent studies of radiosurgical treatment for glomus jugulare. These studies demonstrate that radiosurgery results in similar glomus jugulare tumor control and a superior morbidity profile compared with surgical treatment. In addition, patients treated with radiosurgery usually remain stable clinically or improve. Given the indolent nature of these tumors, however, more follow-up is required to ensure that the immediate benefits are lasting. These preliminary reports demonstrate that the use of radiosurgery as a primary treatment for glomus jugulare should be extended to encompass more of the patients who are currently assigned to microsurgical treatment.


Skull Base ◽  
2007 ◽  
Vol 17 (S 1) ◽  
Author(s):  
Alessandro Bertuccio ◽  
Antonio Fioravanti ◽  
Stefano Bartolini ◽  
Filippo Badaloni ◽  
Fabio Calbucci

Skull Base ◽  
2008 ◽  
Vol 18 (S 01) ◽  
Author(s):  
Hiroaki Motegi ◽  
Shunsuke Terasaka ◽  
Shigeru Yamaguchi ◽  
Hiroyuki Kobayashi ◽  
Katsuyuki Asaoka ◽  
...  

2021 ◽  
Vol 16 (1) ◽  
Author(s):  
Maximilian I. Ruge ◽  
Juman Tutunji ◽  
Daniel Rueß ◽  
Eren Celik ◽  
Christian Baues ◽  
...  

Abstract Background For meningiomas, complete resection is recommended as first-line treatment while stereotactic radiosurgery (SRS) is established for meningiomas of smaller size considered inoperable. If the patient´s medical condition or preference excludes surgery, SRS remains a treatment option. We evaluated the efficacy and safety of SRS in a cohort comprising these cases. Methods In this retrospective single-centre analysis we included patients receiving single fraction SRS either by modified LINAC or robotic guidance by Cyberknife for potentially resectable intracranial meningiomas. Treatment-related adverse events as well as local and regional control rates were determined from follow-up imaging and estimated by the Kaplan–Meier method. Results We analyzed 188 patients with 218 meningiomas. The median radiological, and clinical follow-up periods were 51.4 (6.2–289.6) and 55.8 (6.2–300.9) months. The median tumor volume was 4.2 ml (0.1–22), and the mean marginal radiation dose was 13.0 ± 3.1 Gy, with reference to the 80.0 ± 11.2% isodose level. Local recurrence was observed in one case (0.5%) after 239 months. The estimated 2-, 5-, 10- and 15-year regional recurrence rates were 1.5%, 3.0%, 6.6% and 6.6%, respectively. Early adverse events (≤ 6 months after SRS) occurred in 11.2% (CTCEA grade 1–2) and resolved during follow-up in 7.4% of patients, while late adverse events were documented in 14.4% (grade 1–2; one case grade 3). Adverse effects (early and late) were associated with the presence of symptoms or neurological deficits prior to SRS (p < 0.03) and correlated with the treatment volume (p < 0.02). Conclusion In this analysis SRS appears to be an effective treatment for patients with meningiomas eligible for complete resection and provides reliable long-term local tumor control with low rates of mild morbidity.


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