Synthesis of some new azole, azepine, pyridine, and pyrimidine derivatives using 6-hydroxy-4H-4-oxo[1]-benzopyran-3- carboxaldehyde as a versatile starting material

2005 ◽  
Vol 16 (1) ◽  
pp. 20-27 ◽  
Author(s):  
A. H. Abdel-Rahman ◽  
M. A. A. Hammouda ◽  
S. I. El-Desoky
Keyword(s):  
Starting Material ◽  
Pyrimidine Derivatives ◽  
Pyridine And Pyrimidine Derivatives

scholarly journals A Proline and 4‐Hydroxyproline Based Approach to Enantiopure Pyrrolidin‐2‐yl‐Substituted Pyridine and Pyrimidine Derivatives

2021 ◽  
Author(s):  
Benjamin Brennecke ◽  
Alicia Castelló Micó ◽  
Lars Selter ◽  
Matteo Accorsi ◽  
Reinhold Zimmer ◽  
...  
Keyword(s):  
Pyrimidine Derivatives ◽  
Pyridine And Pyrimidine Derivatives

scholarly journals Synthesis and Anti-Inflammatory Activities of Some New Substituted Benzocarboxamide Pyrimidine Derivatives Using N-(4-Acetylphenyl)-5-chloro-2-methoxybenzamide as Starting Material

2014 ◽  
Vol 26 (24) ◽  
pp. 8514-8520
Author(s):  
Azza A. Hussain ◽  
Mohamed M. Abdulla ◽  
Abd El-Galil E. Amr ◽  
Mohamed A. Al-Omar ◽  
Ahmed F.A. Shalaby
Keyword(s):  
Starting Material ◽  
Pyrimidine Derivatives ◽  
Anti Inflammatory

ChemInform Abstract: Synthesis of Some New Pyridine and Pyrimidine Derivatives Containing Benzothiazole Moiety.

ChemInform ◽  
2013 ◽  
Vol 44 (47) ◽  
pp. no-no
Author(s):  
Khaled S. Mohamed ◽  
Nayra M. Abdulaziz ◽  
Ahmed A. Fadda
Keyword(s):  
Pyrimidine Derivatives ◽  
Pyridine And Pyrimidine Derivatives

scholarly journals Fluorescent property of 3-hydroxymethyl imidazo[1,2-a]pyridine and pyrimidine derivatives

2012 ◽  
Vol 6 (1) ◽  
Author(s):  
Stephania Velázquez-Olvera ◽  
Héctor Salgado-Zamora ◽  
Manuel Velázquez-Ponce ◽  
Elena Campos-Aldrete ◽  
Alicia Reyes-Arellano ◽  
...  
Keyword(s):  
Fluorescent Property ◽  
Pyrimidine Derivatives ◽  
Pyridine And Pyrimidine Derivatives

scholarly journals The Flögel-three-component reaction with dicarboxylic acids – an approach to bis(β-alkoxy-β-ketoenamides) for the synthesis of complex pyridine and pyrimidine derivatives

2014 ◽  
Vol 10 ◽  
pp. 394-404 ◽  
Author(s):  
Mrinal K Bera ◽  
Moisés Domínguez ◽  
Paul Hommes ◽  
Hans-Ulrich Reissig
Keyword(s):  
Dft Calculations ◽  
Carboxylic Acids ◽  
Aromatic Compounds ◽  
Dicarboxylic Acids ◽  
Membered Ring ◽  
Simple Synthesis ◽  
Pyrimidine Derivatives ◽  
Three Component Reaction ◽  
Palladium Catalyzed ◽  
Pyridine And Pyrimidine Derivatives

An extension of the substrate scope of the Flögel-three-component reaction of lithiated alkoxyallenes, nitriles and carboxylic acids is presented. The use of dicarboxylic acids allowed the preparation of symmetrical bis(β-ketoenamides) from simple starting materials in moderate yields. Cyclocondensations of these enamides to 4-hydroxypyridine derivatives or to functionalized pyrimidines efficiently provided symmetrically and unsymmetrically substituted fairly complex (hetero)aromatic compounds containing up to six conjugated aryl and hetaryl groups. In addition, subsequent functionalizations of the obtained heterocycles by palladium-catalyzed couplings or by oxidations are reported. We also describe the simple synthesis of a structurally interesting macrocyclic bispyrimidine derivative incorporating a 17-membered ring, whose configuration was elucidated by DFT calculations and by subsequent reactions.

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