scholarly journals Functional magnetic resonance imaging responses during perceptual decision‐making at 3 and 7 T in human cortex, striatum, and brainstem

2021 ◽  
Author(s):  
Olympia Colizoli ◽  
Jan Willem de Gee ◽  
Wietske van der Zwaag ◽  
Tobias H. Donner
Keyword(s):  
Magnetic Resonance Imaging ◽  
Decision Making ◽  
Magnetic Resonance ◽  
Functional Magnetic Resonance Imaging ◽  
Functional Magnetic Resonance ◽  
Resonance Imaging ◽  
Perceptual Decision Making ◽  
Human Cortex ◽  
Perceptual Decision

INFLUENCE OF MOTOR FUNCTIONAL MAGNETIC RESONANCE IMAGING ON THE SURGICAL MANAGEMENT OF CHILDREN AND ADOLESCENTS WITH SYMPTOMATIC FOCAL EPILEPSY

Neurosurgery ◽  
2009 ◽  
Vol 64 (5) ◽  
pp. 856-864 ◽  
Author(s):  
Xavier De Tiège ◽  
Alan Connelly ◽  
Frédérique Liégeois ◽  
William Harkness ◽  
Chris A. Clark ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Decision Making ◽  
Magnetic Resonance ◽  
Functional Magnetic Resonance Imaging ◽  
Focal Epilepsy ◽  
Decision Making Process ◽  
Functional Magnetic Resonance ◽  
Resonance Imaging ◽  
Central Sulcus ◽  
Presurgical Evaluation

Abstract OBJECTIVE To determine the clinical value of motor functional magnetic resonance imaging (fMRI) in the presurgical evaluation of a large group of children and adolescents with epilepsy caused by lesions close to the central sulcus. METHODS Forty-three patients (19 males; mean age, 13 years) with lesional focal epilepsy underwent motor fMRI as part of a multidisciplinary standardized presurgical evaluation between 2000 and 2006. fMRI data were analyzed using statistical parametric mapping (SPM2) and screened for the presence of movement-related artifacts. The ways in which the results of motor fMRI influenced the decision-making process were reviewed. RESULTS The success rate of motor fMRI was 93% and data were of high quality in 67.5% of the patients. Together with other clinical considerations, motor fMRI results contributed to the surgical management of 32 patients (74%). They helped 1) to determine the type of surgery in 23 patients (72%; 12 cases with and 11 cases without invasive functional mapping), 2) to indicate a reduced benefit-risk ratio with the consequence that surgery was not further considered in 5 patients (16%), and 3) to indicate that surgery was not an appropriate option because of the high risk of motor function deficit in 4 patients (12%). CONCLUSION Motor fMRI can be performed with a high degree of success and good data quality in this population of patients. It has an important additive role in the discussion of the feasibility of resective surgery contributing to the decision-making process for children with epilepsy caused by brain lesions close to the central sulcus.

scholarly journals PC3 - 190 Impact of Functional Magnetic Resonance Imaging on Clinical Decision Making and Outcomes in Patients with Low Grade Gliomas

2016 ◽  
Vol 43 (S4) ◽  
pp. S19-S20
Author(s):  
E. Kosteniuk ◽  
J.C. Lau ◽  
J.F. Megyesi
Keyword(s):  
Magnetic Resonance Imaging ◽  
Decision Making ◽  
Magnetic Resonance ◽  
Functional Magnetic Resonance Imaging ◽  
Fmri Data ◽  
Low Grade ◽  
Functional Magnetic Resonance ◽  
Resonance Imaging ◽  
The Impact

This study aims to evaluate the impact of preoperative functional magnetic resonance imaging (fMRI) on low grade glioma (LGG) patients’ outcomes and surgical planning. Methods In this retrospective matched cohort study of a single surgeon’s patients, we are comparing two groups of LGG patients (WHO grade II) based on exposure to fMRI. Sixteen LGG patients who underwent fMRI were selected, and 32 control (non-fMRI exposed) patients are being selected through propensity score matching from a pool of 764 brain tumour patients. To assess the impact of fMRI data on clinicians’ decision making process, neurosurgeons within a single centre are completing questionnaires regarding treatment options for each LGG fMRI patient based on clinical data and structural imaging before and after fMRI. Results Within the group of 16 LGG patients who have undergone fMRI studies over a 12-year period, most patients presented with seizures (81 percent), and most lesions were left-sided (81 percent) and frontal (75 percent). Patients underwent either craniotomy (50 percent), stereotactic biopsy (25 percent) or nonsurgically management (25 percent). In surgical patients, between presurgical assessment and eight week post-surgical follow-up, mean modified Rankin scale improved from 1.80 (sd 0.79) to 1.50 (sd 0.97). In our cohort, 5-year mortality was 12.5 percent (mean follow-up duration 5.46 years). Conclusions Data analysis is ongoing with plans to compare relevant patient demographics and outcomes, and to analyse questionnaires to elucidate how surgeons incorporate fMRI data into their therapeutic approach.

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