scholarly journals Striatal networks for tinnitus treatment targeting

2021 ◽  
Author(s):  
Leighton B. N. Hinkley ◽  
Paul S. Larson ◽  
Jennifer Henderson Sabes ◽  
Danielle Mizuiri ◽  
Carly Demopoulos ◽  
...  
Keyword(s):  
Tinnitus Treatment ◽  
Treatment Targeting

Biologic Therapy in Psoriasis (Part II): Efficacy and Safety of New Treatment Targeting IL23/IL-17 Pathways

2018 ◽  
Vol 18 (12) ◽  
pp. 964-978 ◽  
Author(s):  
Elisa Molinelli ◽  
Anna Campanati ◽  
Valerio Brisigotti ◽  
Annamaria Offidani
Keyword(s):  
Biologic Therapy ◽  
Efficacy And Safety ◽  
New Treatment ◽  
Treatment Targeting

Analysis of Gabapentin’s Efficacy in Tinnitus Treatment: A Systematic Review

2021 ◽  
pp. 000348942110189
Author(s):  
Matheus Pedrosa Tavares ◽  
Fayez Bahmad
Keyword(s):  
Systematic Review ◽  
Controlled Trial ◽  
Critical Evaluation ◽  
Outcome Study ◽  
Qualitative Synthesis ◽  
Eligibility Criteria ◽  
Double Blind ◽  
Randomized Controlled ◽  
Study Selection ◽  
Tinnitus Treatment

Objectives: Tinnitus can be a chronic symptom that brings disability and distress. Some studies suggested that gabapentin might be effective on tinnitus relief. The objective of the study is to perform a systematic review in order to evaluate the efficacy of oral gabapentin in patients with tinnitus. Methods: A literature search was conducted in English and following the recommendations from PRISMA. The terms used were: (“tinnitus” OR “subjective tinnitus”) AND (“gabapentin”). The study selection was performed following the eligibility criteria in accordance to the PICOS (population, intervention, comparison, outcome, study design) strategy—patients with tinnitus; oral gabapentin; placebo; reduction of tinnitus severity questionnaires scores; prospective, double-blind, randomized controlled trial, respectively. The selected studies were included in qualitative synthesis. The studies were analyzed according to Joanna Briggs Institute’s critical appraisal checklist for randomized controlled trials. Results: One hundred twenty-one studies were found in 9 databases and 8 studies were found in gray literature. After study selection, 6 articles were read in full. Then, 2 studies were excluded and 4 were included in qualitative synthesis. All 4 articles were analyzed according to critical evaluation checklist. Conclusions: There is insufficient evidence to recommend the use of gabapentin for patients with tinnitus.

scholarly journals Perception Mechanism of Bone-Conducted Ultrasound and Its Clinical Use

2021 ◽  
Vol 11 (2) ◽  
pp. 244-253
Author(s):  
Tadashi Nishimura ◽  
Tadao Okayasu ◽  
Akinori Yamashita ◽  
Hiroshi Hosoi ◽  
Tadashi Kitahara
Keyword(s):  
Hearing Aids ◽  
Hearing Aid ◽  
Bone Conduction ◽  
Speech Signals ◽  
Clinical Use ◽  
Reported Speech ◽  
Sound Therapy ◽  
Profound Deafness ◽  
Tinnitus Treatment

It is generally believed that ultrasound cannot be heard. However, ultrasound is audible when it is presented through bone conduction. Bone-conducted ultrasound (BCU) has unique characteristics; the most interesting is its perception in patients with profound deafness. Some patients can perceive it and discriminate speech-modulated BCU. Previous reports have suggested that BCU can be used for a hearing aid or tinnitus sound therapy. In this review, the perception of BCU at both the peripheral and central levels was investigated based on previous studies, although some of them remain controversial. We also investigated the clinical use of BCU. To develop hearing aids utilizing BCU, the encoding of speech signals into BCU has to be established. The outcomes of the reported speech modulations were evaluated. Furthermore, the suppression of tinnitus by BCU was reviewed, and the feasibility of the application of BCU to tinnitus treatment was investigated.

08:18: Combined Temporal and Prefrontal TMS for Tinnitus Treatment

2007 ◽  
Vol 137 (2_suppl) ◽  
pp. P119-P120 ◽  
Author(s):  
Patrick J. Antonelli ◽  
Serge A. Martinez ◽  
Tobias Kleinjung ◽  
Peter Eichhammer ◽  
Michael Landgrebe ◽  
...  
Keyword(s):  
Tinnitus Treatment

scholarly journals MP64-20 A NOVEL NITROXOLINE TREATMENT, TARGETING THE PI3K PATHWAY, IN COMBINATION WITH PD-1 BLOCKAGE, EXERTS A POTENT PROSTATE CANCER ANTI-TUMOR EFFECT

2018 ◽  
Vol 199 (4S) ◽  
Author(s):  
Naijin Xu ◽  
Chaoming Li ◽  
Masami Watanabe ◽  
Abai Xu ◽  
Chunxiao Liu ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Pi3k Pathway ◽  
Treatment Targeting

Abstract 1453: Antibiotic treatment targeting gram negative bacteria prevents neratinib-induced diarrhea in rats

2021 ◽  
Author(s):  
Kate R. Secombe ◽  
Imogen A. Ball ◽  
Anthony D. Wignall ◽  
Emma Bateman ◽  
Irmina Diala ◽  
...  
Keyword(s):  
Antibiotic Treatment ◽  
Gram Negative Bacteria ◽  
Gram Negative ◽  
Treatment Targeting
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