scholarly journals Associations of gestational age and birth anthropometric indicators with brain white matter maturation in full‐term neonates

2019 ◽  
Author(s):  
Chao Jin ◽  
Yanyan Li ◽  
Xianjun Li ◽  
Congcong Liu ◽  
Miaomiao Wang ◽  
...  
Keyword(s):  
White Matter ◽  
Gestational Age ◽  
Full Term ◽  
Term Neonates ◽  
Anthropometric Indicators ◽  
Brain White Matter ◽  
White Matter Maturation

Radiologic differences in white matter maturation between preterm and full-term infants: TBSS study

2012 ◽  
Vol 43 (5) ◽  
pp. 612-619 ◽  
Author(s):  
Ah Young Lee ◽  
Sung Ho Jang ◽  
Eunsil Lee ◽  
Sang Ho Ahn ◽  
Hee Kyung Cho ◽  
...  
Keyword(s):  
White Matter ◽  
Full Term ◽  
Term Infants ◽  
White Matter Maturation

Hypoglycaemia and seizures in large-for-gestational-age (LGA) full-term neonates

2007 ◽  
Vol 95 (7) ◽  
pp. 874-876
Author(s):  
Floris Groenendaal ◽  
Patty M. Elferink-Stinkens ◽  
Keyword(s):  
Gestational Age ◽  
Full Term ◽  
Large For Gestational Age ◽  
Term Neonates

scholarly journals Gestational Age at Birth and Brain White Matter Development in Term-Born Infants and Children

2017 ◽  
Vol 38 (12) ◽  
pp. 2373-2379 ◽  
Author(s):  
X. Ou ◽  
C.M. Glasier ◽  
R.H. Ramakrishnaiah ◽  
A. Kanfi ◽  
A.C. Rowell ◽  
...  
Keyword(s):  
White Matter ◽  
Gestational Age ◽  
Infants And Children ◽  
Brain White Matter ◽  
White Matter Development ◽  
Gestational Age At Birth ◽  
Age At Birth

scholarly journals Diffusion Tensor Imaging Assessment of Brain White Matter Maturation During the First Postnatal Year

2007 ◽  
Vol 189 (2) ◽  
pp. 476-486 ◽  
Author(s):  
James M. Provenzale ◽  
Luxia Liang ◽  
David DeLong ◽  
Leonard E. White
Keyword(s):  
Diffusion Tensor Imaging ◽  
White Matter ◽  
Diffusion Tensor ◽  
Brain White Matter ◽  
White Matter Maturation

Clot formation of neonates tested by thromboelastography correlates with gestational age

2010 ◽  
Vol 103 (02) ◽  
pp. 344-350 ◽  
Author(s):  
Tzipi Strauss ◽  
Yael Levy-Shraga ◽  
Bruria Ravid ◽  
Irit Schushan-Eisen ◽  
Ayala Maayan-Metzger ◽  
...  
Keyword(s):  
Cord Blood ◽  
Gestational Age ◽  
Blood Clot ◽  
Full Term ◽  
Clot Formation ◽  
Clotting Time ◽  
Term Infants ◽  
Term Neonates ◽  
Pregnancy And Delivery ◽  
Clot Formation Time

SummaryEvaluation of clot formation in neonates is troublesome. Our aim was to investigate cord blood clot formation of pre-term versus full-term infants and adults, using rotating thromboelastogram (ROTEM®, Pentafarm, Munich, Germany). ROTEM was investigated in cord blood of 184 full-term and 47 pre-term infants. Measurements of the clotting time (CT), clot formation time (CFT) and maximal clot firmness (MCF) were obtained in order to asses reference values for this age group, and compare between full-term and pre-term neonates and compared to adult controls. For each infant demographic information and data regarding pregnancy and delivery were gathered. Infants were prospectively followed until discharge. CT and CFT were significantly shorter among pre-term and term infants as compared to adults [median CT: 185, 194, 293 seconds respectively, p≤0.001, CFT: 80, 76, 103 seconds respectively, p≤0.001). MCF was lower in pre-term and term as compared to adults (p≤0.001) with significantly lower values in pre-term as compared to full-term neonates (p=0.004). Clotting time and MCF correlated with gestational age (R=0.132, p=0.045, R= 0.259, p<0.001, respectively). No association was found between any ROTEM values and the occurrence of post-natal complications in infants of our study group. This is the first study assessing clot formation by ROTEM in pre-term infants. Clot formation parameters of term and premature infants correlated with gestational age. The predictive value of clot formation tests in neonates deserves further attention.

scholarly journals Effect of early and delayed cord clamping on hemoglobin and hematocrit among full term neonates.

2021 ◽  
Vol 28 (08) ◽  
pp. 1114-1119
Author(s):  
Saqib Aslam ◽  
◽  
Sadaf Minhas ◽  
Muhammad Azhar Farooq ◽  
Beenish Bashir Mughal ◽  
...  
Keyword(s):  
Birth Weight ◽  
Gestational Age ◽  
Full Term ◽  
P Value ◽  
Delayed Cord Clamping ◽  
Term Neonates ◽  
Cord Clamping ◽  
Significant Difference ◽  
Early Cord Clamping ◽  
The Mean

Objective: To compare the mean hemoglobin levels and frequency of polycythemia in full term neonates after early and delayed cord clamping. Study Design: Randomized Controlled Trial. Setting: KRL General Hospital Islamabad (Labor Room/ Neonatology). Periods: December 2017 to June 2018. Material & Methods: 190 full term neonates were selected and divided into 2 equal groups randomly: Early cord clamping group after delivery and late cord clamping group. Two hours after clamping the venous blood samples were taken for the hemoglobin and hematocrit levels. Mean and standard deviation were calculated for gestational age, birth weight, hemoglobin and hematocrit. Frequency and proportions were calculated for gender and polycythemia. Results: Mean gestational age of the mothers was 39.27 ± 1.50 weeks. Of 190 neonates, 91 (47.9%) were males, 99 (52.1%) were females. Mean birth weight was 3.64 ± 0.72 kg while mean Hb and HCT levels were 16.07 ± 2.30 g/dl and 63.26 ± 5.32% respectively. Keeping cut off value of 13.5 g/dl of Hb to label anemia or no, 35 (18.4%) neonates were anemic in this study. The polycythemia (HCT >65%) was present in 72 (37.9%) of neonates. There was no difference between groups in terms of gender, anemia, gestational age and birth weight (p values 0.663, 0.852, 0.700 and 0.491 respectively). The distribution of polycythemia was different among groups (p value 0.007). The mean hemoglobin level in group A was 15.52 ± 1.90 g/dl while in group B it was 16.62 ± 2.53 g/dl (p value 0.001). Mean Hb levels were statistically not different among some of the groups (gestational age <40 weeks, birth weight <4 kg) while HCT levels are significantly different among male group and category of birth weight >4 kg. Rest of the stratification groups showed significant difference. Conclusion: The delayed cord clamping in neonates results in increased mean hemoglobin and hematocrit levels with increased frequency of polycythemia as compared to early cord clamping.

scholarly journals Application value of three-dimensional arterial spin labeling perfusion imaging in investigating cerebral blood flow dynamics in normal full-term neonates

2019 ◽  
Vol 19 (1) ◽  
Author(s):  
Jia-Ning Wang ◽  
Jia Li ◽  
Huai-Jun Liu ◽  
Xiao-Ping Yin ◽  
Huan Zhou ◽  
...  
Keyword(s):  
Blood Flow ◽  
Cerebral Blood Flow ◽  
White Matter ◽  
Basal Ganglia ◽  
Three Dimensional ◽  
Full Term ◽  
Term Neonates ◽  
Corona Radiata ◽  
Frontal White Matter ◽  
Blood Flow Dynamics

Abstract Background This study aims to investigate the application value of three-dimensional arterial spin labeling (3DASL) in investigating cerebral blood flow dynamics in full-term neonates. Methods A total of 60 full-term neonates without known intracranial pathology were recruited for 3DASL examination. These neonates were divided into three groups: 1–3 day group, 4–7 day group, and 8–15 day group. On the cerebral blood flow (CBF) images, regions of interest (ROI) were selected from the frontal white matter, parietal white matter, basal ganglia, corona radiata, thalamus and brainstem, and the CBF values of each ROI were recorded. The CBF values of ROIs at bilaterally symmetric locations, the values of each ROI between males and females, and the values of each ROI among these three different age groups were compared. Results The difference in CBF values of the frontal white matter, parietal white matter, basal ganglia, corona radiata and thalamus at the bilateral symmetric positions were not statistically significant. There was no statistical difference in the CBF values of each brain region between the male and female groups. The CBF values at the basal ganglia region, corona radiata and parietal white matter were higher in the 8–15 day group, when compared to the 1–3 day and 4–7 day groups (P < 0.05). The CBF value at the basal ganglia region was higher in the 4–7 day group, when compared to the 1–3 day group (P < 0.05). The CBF value at the frontal white matter was lower in the 4–7 day group, when compared to the 1–3 day and 8–15 day group (P < 0.05). The CBF value at the brainstem was higher in the 4–7 day group, when compared to the 1–3 day and 8–15 day groups (P < 0.05). Conclusion The 3DASL can quantitatively measure CBF, and be used to evaluate cerebral hemodynamics in neonates. The basal ganglia region and corona radiata CBF increases with the increase in neonatal diurnal age.

scholarly journals Diminished HLA-DR expression on monocyte and dendritic cell subsets indicating impairment of cellular immunity in pre-term neonates: a prospective observational analysis

2015 ◽  
Vol 43 (5) ◽  
Author(s):  
Joerg C. Schefold ◽  
Linn Porz ◽  
Barbara Uebe ◽  
Holger Poehlmann ◽  
Stephan von Haehling ◽  
...  
Keyword(s):  
Gestational Age ◽  
Human Leukocyte ◽  
Severe Infection ◽  
Full Term ◽  
Term Neonates ◽  
Observational Analysis ◽  
Leukocyte Antigen ◽  
Hla Dr ◽  
Leukocyte Counts ◽  
Antigen Presenting

AbstractThe risk of neonates for severe infection/sepsis is reciprocally proportional to gestational age and birth weight. As monocytes and dendritic cells (DC) are recognised key antigen-presenting immune cells, we aimed to elucidate whether neonatal age is associated with reduced expression of human-leukocyte antigen-DR (HLA-DR) antigens on subsets of monocytes and DCs.Forty-three consecutive neonates (20 male, mean gestational age 236.0±26.8 days; mean 1-min Apgar score 7.5±2.0) were included in a monocentric prospective observational analysis. Patients were grouped according to gestational age (n=15 full-term, n=28 pre-term defined as <33 weeks). Ten healthy adult volunteers were assessed also. Flow-cytometric assessment of HLA-DR expression was performed in subsets of peripheral blood myeloid and plasmacytoid DCs (MDC and PDC) and monocytes (CD14At birth, leukocyte counts were increased in full-term neonates. Monocyte counts were significantly increased in neonates when compared with adults (all P<0.05). A significant numerical increase of CD14We observed a markedly diminished HLA-DR expression on monocyte and DC subsets in pre-term and full-term neonates, which may contribute to impaired antimicrobial defence mechanisms in the early days of life.

scholarly journals Capillary blood reference intervals for platelet parameters in healthy full-term neonates in China

2020 ◽  
Author(s):  
Dongyan Cui ◽  
Yan Hou ◽  
Ling Feng ◽  
Guo Li ◽  
Chi Zhang ◽  
...  
Keyword(s):  
Platelet Count ◽  
Gestational Age ◽  
Reference Interval ◽  
Reference Intervals ◽  
Capillary Blood ◽  
Full Term ◽  
Term Neonates ◽  
First Time ◽  
Early Phases

Abstract Background No consensus has been reached on reference intervals for platelet parameters in full-term neonates. We aimed to establish neonatal capillary blood reference intervals for platelet parameters and evaluate influences of gender, gestational age and postnatal age on platelet parameters. Methods This study was implemented in 594 healthy full-term neonates from 12 to 84 hours of age, using SYSMEX XN-9000 haematology automatic analyser by means of capillary blood. Reference intervals for platelet parameters were defined by an interval of 2.5th − 97.5th percentiles. Results Capillary reference interval for platelet count was (152–464) × 109/L. No significance was found between gender-divided reference intervals for platelet parameters. The values of platelet count changed significantly across gestational age and postnatal age. Reference intervals for other platelet parameters were affected by these factors to a different extent. Conclusions We established capillary blood reference intervals for platelet parameters in the early phases after birth of full-term neonates in China for the first time.

Hypoglycaemia and seizures in large-for-gestational-age (LGA) full-term neonates

2006 ◽  
Vol 95 (7) ◽  
pp. 874-876 ◽  
Author(s):  
Floris Groenendaal ◽  
Patty Elferink-Stinkens ◽  
The Netherlands Perinatal Registry
Keyword(s):  
Gestational Age ◽  
Full Term ◽  
Large For Gestational Age ◽  
Term Neonates
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