scholarly journals Neural correlates of reduced depressive symptoms following cognitive training for chronic traumatic brain injury

2018 ◽  
Vol 39 (7) ◽  
pp. 2955-2971 ◽  
Author(s):  
Kihwan Han ◽  
David Martinez ◽  
Sandra B. Chapman ◽  
Daniel C. Krawczyk
Keyword(s):  
Traumatic Brain Injury ◽  
Depressive Symptoms ◽  
Brain Injury ◽  
Cognitive Training ◽  
Neural Correlates

scholarly journals Traumatic Brain Injury: Effect of Litigation Status on Executive Functioning—A Pilot Study

2020 ◽  
Author(s):  
Simi Prakash K. ◽  
Rajakumari P. Reddy ◽  
Anna R. Mathulla ◽  
Jamuna Rajeswaran ◽  
Dhaval P. Shukla
Keyword(s):  
Traumatic Brain Injury ◽  
Working Memory ◽  
Depressive Symptoms ◽  
Brain Injury ◽  
Concept Formation ◽  
Verbal Working Memory ◽  
Self Report ◽  
Semantic Fluency ◽  
Set Shifting ◽  
Wide Range

AbstractTraumatic brain injury (TBI) is associated with a wide range of physiological, behavioral, emotional, and cognitive sequelae. Litigation status is one of the many factors that has an impact on recovery. The aim of this study was to compare executive functions, postconcussion, and depressive symptoms in TBI patients with and without litigation. A sample of 30 patients with TBI, 15 patients with litigation (medicolegal case [MLC]), and 15 without litigation (non-MLC) was assessed. The tools used were sociodemographic and clinical proforma, executive function tests, Rivermead Post-Concussion Symptom Questionnaire, and Beck Depression Inventory. Assessment revealed that more than 50% of patients showed deficits in category fluency, set shifting, and concept formation. The MLC group showed significant impairment on verbal working memory in comparison to the non-MLC group. The performance of both groups was comparable on tests of semantic fluency, visuospatial working memory, concept formation, set shifting, planning, and response inhibition. The MLC group showed more verbal working memory deficits in the absence of significant postconcussion and depressive symptoms on self-report measures.

scholarly journals Neural correlates of motor dysfunction in children with traumatic brain injury: exploration of compensatory recruitment patterns

Brain ◽  
2009 ◽  
Vol 132 (3) ◽  
pp. 684-694 ◽  
Author(s):  
K. Caeyenberghs ◽  
N. Wenderoth ◽  
B. C. M. Smits-Engelsman ◽  
S. Sunaert ◽  
S. P. Swinnen
Keyword(s):  
Traumatic Brain Injury ◽  
Brain Injury ◽  
Neural Correlates ◽  
Motor Dysfunction ◽  
Recruitment Patterns

The Benefits of TeleCognitive Training on Depressive Symptoms in Adults with Traumatic Brain Injury

2015 ◽  
Vol 96 (10) ◽  
pp. e105
Author(s):  
Benjamin Douglas Eschler ◽  
Asha K. Vas ◽  
Molly Keebler ◽  
Sandi Chapman ◽  
Kay Moolenijzer
Keyword(s):  
Traumatic Brain Injury ◽  
Depressive Symptoms ◽  
Brain Injury

CogSMART Compensatory Cognitive Training for Traumatic Brain Injury

2015 ◽  
Vol 30 (6) ◽  
pp. 391-401 ◽  
Author(s):  
Elizabeth W. Twamley ◽  
Kelsey R. Thomas ◽  
Amber M. Gregory ◽  
Amy J. Jak ◽  
Mark W. Bondi ◽  
...  
Keyword(s):  
Traumatic Brain Injury ◽  
Brain Injury ◽  
Cognitive Training

scholarly journals Panic Disorder Induced by the Coronavirus Disease Pandemic in a Patient with Organic Mood Disorder Successfully Treated with Vortioxetine

2020 ◽  
Vol 2020 ◽  
pp. 1-3
Author(s):  
Reiji Yoshimura ◽  
Naomichi Okamoto ◽  
Yuki Konishi ◽  
Atsuko Ikenouchi
Keyword(s):  
Traumatic Brain Injury ◽  
Depressive Symptoms ◽  
Brain Injury ◽  
Panic Disorder ◽  
Mood Disorder ◽  
Traffic Accident ◽  
Panic Attacks ◽  
Depressive State ◽  
Multiple Episodes

We present a case of panic disorder induced by the coronavirus disease (COVID-19) pandemic in a patient with an organic mood disorder. The patient was a 62-year-old woman with mild mood swings and reduced motivation and volition caused by a traumatic brain injury after a traffic accident. She was maintained on carbamazepine (600 mg/day). When the COVID-19 outbreak occurred in Japan, she developed concerns regarding the illness and complained of multiple episodes of panic attacks. Further, her depressive symptoms worsened. Thus, vortioxetine was added to the ongoing CBZ treatment. Four weeks after initiating vortioxetine treatment, the symptoms of panic disorder and depressive state were ameliorated. The present case suggests that vortioxetine augmentation can improve symptoms of depressive state and panic disorder induced by the COVID-19 pandemic.

scholarly journals Cognitive Training in Young Patients With Traumatic Brain Injury: A Fixel-Based Analysis

2019 ◽  
Vol 33 (10) ◽  
pp. 813-824 ◽  
Author(s):  
Helena Verhelst ◽  
Diana Giraldo ◽  
Catharine Vander Linden ◽  
Guy Vingerhoets ◽  
Ben Jeurissen ◽  
...  
Keyword(s):  
Traumatic Brain Injury ◽  
Brain Injury ◽  
White Matter ◽  
Cognitive Functioning ◽  
Cognitive Training ◽  
Cognitive Assessment ◽  
Cognitive Intervention ◽  
The Body ◽  
Precentral Gyrus ◽  
Time Point

Background. Traumatic brain injury (TBI) is associated with altered white matter organization and impaired cognitive functioning. Objective. We aimed to investigate changes in white matter and cognitive functioning following computerized cognitive training. Methods. Sixteen adolescents with moderate-to-severe TBI (age 15.6 ± 1.8 years, 1.2-4.6 years postinjury) completed the 8-week BrainGames program and diffusion weighted imaging (DWI) and cognitive assessment at time point 1 (before training) and time point 2 (after training). Sixteen healthy controls (HC) (age 15.6 ± 1.8 years) completed DWI assessment at time point 1 and cognitive assessment at time point 1 and 2. Fixel-based analyses were used to examine fractional anisotropy (FA), mean diffusivity (MD), and fiber cross-section (FC) on a whole brain level and in tracts of interest. Results. Patients with TBI showed cognitive impairments and extensive areas with decreased FA and increased MD together with an increase in FC in the body of the corpus callosum and left superior longitudinal fasciculus (SLF) at time point 1. Patients improved significantly on the inhibition measure at time point 2, whereas the HC group remained unchanged. No training-induced changes were observed on the group level in diffusion metrics. Exploratory correlations were found between improvements on verbal working memory and reduced MD of the left SLF and between increased performance on an information processing speed task and increased FA of the right precentral gyrus. Conclusions. Results are indicative of positive effects of BrainGames on cognitive functioning and provide preliminary evidence for neuroplasticity associated with cognitive improvements following cognitive intervention in TBI.

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