scholarly journals Quantitative representations of an exaggerated anxiety response in the brain of female spider phobics-a parametric fMRI study

2017 ◽  
Vol 38 (6) ◽  
pp. 3025-3038 ◽  
Author(s):  
Anna Zilverstand ◽  
Bettina Sorger ◽  
Anita Kaemingk ◽  
Rainer Goebel
Keyword(s):  
Fmri Study ◽  
Anxiety Response ◽  
The Brain

How does the brain process time? insights from an event-related fMRI study

NeuroImage ◽  
2000 ◽  
Vol 11 (5) ◽  
pp. S49
Author(s):  
D.L. Harrington ◽  
L.A. Mead ◽  
A.R. Mayer ◽  
K.Y. Haaland ◽  
S.M. Rao
Keyword(s):  
Process Time ◽  
Brain Process ◽  
Fmri Study ◽  
The Brain

scholarly journals Neurodegeneration in friedreich's ataxia is associated with a mixed activation pattern of the brain. A fMRI study

2011 ◽  
Vol 33 (8) ◽  
pp. 1780-1791 ◽  
Author(s):  
Andrea Ginestroni ◽  
Stefano Diciotti ◽  
Paolo Cecchi ◽  
Ilaria Pesaresi ◽  
Carlo Tessa ◽  
...  
Keyword(s):  
Friedreich’S Ataxia ◽  
Friedreich's Ataxia ◽  
Activation Pattern ◽  
Fmri Study ◽  
The Brain

Future Trends in Functional MRI

2018 ◽  
pp. 230-240
Keyword(s):  
Imaging Technique ◽  
Diffusion Imaging ◽  
Tumor Resection ◽  
Clot Lysis ◽  
Activation Patterns ◽  
Imaging Tool ◽  
Fmri Study ◽  
Activation Response ◽  
Brain Fmri ◽  
The Brain

While MRI became a standard workhorse in neurology/neurosurgery within a few years of installation of the first MRI unit, fMRI, in spite of being a powerful imaging tool, remains primarily a research tool, even though the first fMRI study was published 25 years ago. Scientifically, fMRI has made a major impact, judging by the number of PubMed citations and publications in high-impact journals. In cognitive neuroscience, fMRI is the most commonly used imaging technique in published peer-reviewed articles. fMRI is used clinically for preoperative brain mapping in neurosurgery to delineate the proximity of the lesion (tumor) to eloquent areas of the brain, with the aim of achieving adequate tumor resection with minimal functional damage to the brain. fMRI connectivity and activation maps have identified altered activation patterns and resting-state networks in psychiatric disorders like schizophrenia, bipolar disorder, autism, and Alzheimer’s disease, but fMRI is still not a standard diagnostic procedure in psychiatry. Diffusion imaging technique is being used for triaging stroke patients who are likely to respond to stroke therapy (embolectomy and/or clot lysis). Meanwhile, major collaborative fMRI studies are in progress in many institutions to collect normative data on connectivity, activation response, and behavioral response as well as correlation among them. Studies focused on specific neuropsychiatric disorders also have been initiated by the National Institutes of Health. All this is a reflection of the huge potential application of fMRI in clinical practice envisioned by the scientific community.

scholarly journals Differential Hemodynamic Response in Affective Circuitry with Aging: An fMRI Study of Novelty, Valence, and Arousal

2011 ◽  
Vol 23 (5) ◽  
pp. 1027-1041 ◽  
Author(s):  
Yoshiya Moriguchi ◽  
Alyson Negreira ◽  
Mariann Weierich ◽  
Rebecca Dautoff ◽  
Bradford C. Dickerson ◽  
...  
Keyword(s):  
Functional Connectivity ◽  
Affect Regulation ◽  
Time Course ◽  
Older Individuals ◽  
Peak Response ◽  
Age Related ◽  
Fmri Study ◽  
Bold Responses ◽  
Valence And Arousal ◽  
The Brain

Emerging evidence indicates that stimulus novelty is affectively potent and reliably engages the amygdala and other portions of the affective workspace in the brain. Using fMRI, we examined whether novel stimuli remain affectively salient across the lifespan, and therefore, whether novelty processing—a potentially survival-relevant function—is preserved with aging. Nineteen young and 22 older healthy adults were scanned during observing novel and familiar affective pictures while estimating their own subjectively experienced aroused levels. We investigated age-related difference of magnitude of activation, hemodynamic time course, and functional connectivity of BOLD responses in the amygdala. Although there were no age-related differences in the peak response of the amygdala to novelty, older individuals showed a narrower, sharper (i.e., “peakier”) hemodynamic time course in response to novel stimuli, as well as decreased connectivity between the left amygdala and the affective areas including orbito-frontal regions. These findings have relevance for understanding age-related differences in memory and affect regulation.

scholarly journals Language structure in the brain: A fixation-related fMRI study of syntactic surprisal in reading

NeuroImage ◽  
2016 ◽  
Vol 132 ◽  
pp. 293-300 ◽  
Author(s):  
John M. Henderson ◽  
Wonil Choi ◽  
Matthew W. Lowder ◽  
Fernanda Ferreira
Keyword(s):  
Language Structure ◽  
Fmri Study ◽  
The Brain

P18-3 Odors activate selectively the brain areas related on the memory and emotion, by an fMRI study

2010 ◽  
Vol 121 ◽  
pp. S208
Author(s):  
M. Tonoike ◽  
T. Uno ◽  
T. Yoshida ◽  
L.Q. Wang
Keyword(s):  
Brain Areas ◽  
Fmri Study ◽  
The Brain

scholarly journals An fMRI study of the brain responses of traumatized mothers to viewing their toddlers during separation and play

2011 ◽  
Vol 7 (8) ◽  
pp. 969-979 ◽  
Author(s):  
Daniel S. Schechter ◽  
Dominik A. Moser ◽  
Zhishun Wang ◽  
Rachel Marsh ◽  
XueJun Hao ◽  
...  
Keyword(s):  
Brain Responses ◽  
Fmri Study ◽  
The Brain

Abnormal function of the brain system supporting motivated attention in medicated patients with schizophrenia: an fMRI study

2006 ◽  
Vol 36 (8) ◽  
pp. 1097-1108 ◽  
Author(s):  
PETER F. LIDDLE ◽  
KRISTIN R. LAURENS ◽  
KENT A. KIEHL ◽  
ELTON T. C. NGAN
Keyword(s):  
Basal Forebrain ◽  
Anterior Cingulate ◽  
Orbital Frontal Cortex ◽  
Brain System ◽  
Cerebral Activity ◽  
Auditory Oddball ◽  
Fmri Study ◽  
Motivated Attention ◽  
Subcortical Nuclei ◽  
The Brain

Background. Patients with schizophrenia have an impaired ability to generate activity that is appropriate to current circumstances and goals.Method. We report a study using functional magnetic resonance imaging (fMRI) to examine cerebral activity during a three-tone auditory oddball target detection task in a sample of 28 patients with schizophrenia and 28 healthy controls.Results. The patients exhibited significantly less activation in response to target stimuli relative to baseline in an extensive set of sites in association neocortex, paralimbic cortex, limbic structures and subcortical nuclei, yet demonstrated a normal level of activation in the sensorimotor cortex. Comparison of activity elicited by rare target stimuli with that elicited by equally rare novel stimuli makes it possible to distinguish cerebral activity associated with attention to behaviourally salient stimuli from activity associated with attending to other attention-capturing stimuli. This comparison revealed that the patients with schizophrenia also exhibited a deficit in activation of basal forebrain areas that mediate motivation during the processing of behaviourally salient stimuli, including the amygdala, ventral striatum, orbital frontal cortex and rostral anterior cingulate cortex.Conclusion. Patients with schizophrenia have a deficit in function of the brain system concerned with mediating motivation, in addition to a more general deficit in the cerebral response to attention-captivating stimuli.

Do We Have a “Mental Syllabary” in the Brain? An fMRI Study

Motor Control ◽  
2011 ◽  
Vol 15 (1) ◽  
pp. 34-51 ◽  
Author(s):  
Bettina Brendel ◽  
Michael Erb ◽  
Axel Riecker ◽  
Wolfgang Grodd ◽  
Hermann Ackermann ◽  
...  
Keyword(s):  
Motor Control ◽  
Low Frequency ◽  
Frequency Effect ◽  
Speech Motor Control ◽  
Motor Execution ◽  
Syllable Frequency ◽  
Fmri Study ◽  
The Brain ◽  
Speech Motor

The present study combines functional magnetic resonance imaging (fMRI) and reaction time (RT) measurements to further elucidate the influence of syllable frequency and complexity on speech motor control processes, i.e., overt reading of pseudowords. Tying in with a recent fMRI-study of our group we focused on the concept of a mental syllabary housing syllable sized ready-made motor plans for high- (HF), but not low-frequency (LF) syllables. The RT-analysis disclosed a frequency effect weakened by a simultaneous complexity effect for HF-syllables. In contrast, the fMRI data revealed no effect of syllable frequency, but point to an impact of syllable structure: Compared with CV-items, syllables with a complex onset (CCV) yielded higher hemodynamic activation in motor “execution” areas (left sensorimotor cortex, right inferior cerebellum), which is at least partially compatible with our previous study. We discuss the role of the syllable in speech motor control.

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